LDC4297
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- $37 - $3795
- Product name: LDC4297
- CAS: 1453834-21-3
- MF: C23H28N8O
- MW: 432.52
- EINECS:
- MDL Number:MFCD28411427
- Synonyms:LDC4297;LDC4297(LDC044297);LDC044297;LDC4297;LDC 4297;CS-2539;CS-2540;Pyrazolo[1,5-a]-1,3,5-triazin-4-amine, 8-(1-methylethyl)-2-(3-piperidinyloxy)-N-[[2-(1H-pyrazol-1-yl)phenyl]methyl]-;N-(2-(1H-Pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine
16 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1333DY
- Product descriptionCID78161839
- Packaging1mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1333DY
- Product descriptionCID78161839
- Packaging25mg
- Price$735
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23398
- Product descriptionLDC-4297 ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23398
- Product descriptionLDC-4297 ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23398
- Product descriptionLDC-4297 ≥98%
- Packaging10mg
- Price$283
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23398
- Product descriptionLDC-4297 ≥98%
- Packaging25mg
- Price$573
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6871
- Product descriptionLDC4297 99.14%
- Packaging2mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6871
- Product descriptionLDC4297 99.14%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6871
- Product descriptionLDC4297 99.14%
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6871
- Product descriptionLDC4297 99.14%
- Packaging25mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6871
- Product descriptionLDC4297 99.14%
- Packaging50mg
- Price$690
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6871
- Product descriptionLDC4297 99.14%
- Packaging100mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10143
- Product descriptionLDC-4297 >98%
- Packaging100mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10143
- Product descriptionLDC-4297 >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10143
- Product descriptionLDC-4297 >98%
- Packaging1g
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberL367665
- Product descriptionLDC4297
- Packaging25mg
- Price$3795
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1333DY | CID78161839 | 1mg | $139 | 2021-12-16 | Buy |
| AK Scientific | 1333DY | CID78161839 | 25mg | $735 | 2021-12-16 | Buy |
| Cayman Chemical | 23398 | LDC-4297 ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 23398 | LDC-4297 ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 23398 | LDC-4297 ≥98% | 10mg | $283 | 2024-03-01 | Buy |
| Cayman Chemical | 23398 | LDC-4297 ≥98% | 25mg | $573 | 2024-03-01 | Buy |
| ChemScene | CS-6871 | LDC4297 99.14% | 2mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-6871 | LDC4297 99.14% | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-6871 | LDC4297 99.14% | 10mg | $190 | 2021-12-16 | Buy |
| ChemScene | CS-6871 | LDC4297 99.14% | 25mg | $390 | 2021-12-16 | Buy |
| ChemScene | CS-6871 | LDC4297 99.14% | 50mg | $690 | 2021-12-16 | Buy |
| ChemScene | CS-6871 | LDC4297 99.14% | 100mg | $1200 | 2021-12-16 | Buy |
| DC Chemicals | DC10143 | LDC-4297 >98% | 100mg | $550 | 2021-12-16 | Buy |
| DC Chemicals | DC10143 | LDC-4297 >98% | 250mg | $900 | 2021-12-16 | Buy |
| DC Chemicals | DC10143 | LDC-4297 >98% | 1g | $1800 | 2021-12-16 | Buy |
| TRC | L367665 | LDC4297 | 25mg | $3795 | 2021-12-16 | Buy |
Properties
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:40.0(Max Conc. mg/mL);92.48(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);46.24(Max Conc. mM) form :A crystalline solid
pka :8.69±0.10(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:40.0(Max Conc. mg/mL);92.48(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);46.24(Max Conc. mM) form :A crystalline solid
pka :8.69±0.10(Predicted)
color :White to off-white
Safety Information
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Description
LDC-4297 is an inhibitor of cyclin-dependent kinase 7 (CDK7; IC50 = <5 nM). It is selective for CDK7 over CDK4, CDK6, and CDK9 (IC50s = >10, >10, and 1.71 μM), however, it also inhibits CDK2 and CDK1 (IC50s = 6.4 and 53.7 nM, respectively). LDC-4297 (10-100 nM) induces apoptosis in A549, HeLa, and HCT116 cancer cells in a concentration-dependent manner. It inhibits human cytomegalovirus (HCMV) replication in human fibroblasts (EC50 = 24.5 nM). LDC-4297 also reduces replication of Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae family viruses (EC50s = 0.02-1.13 μM).Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.
Shanghai JiYi Biotechnology Co. Ltd.