LDN-193189 HCl
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- $25 - $2023
- Product name: LDN-193189 HCl
- CAS: 1062368-62-0
- MF: C25H23ClN6
- MW: 442.94332
- EINECS:
- MDL Number:MFCD17392570
- Synonyms:4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline hydrochloride;4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyriMidin-3-yl)quinoline HCl;LDN193189 (Hydrochloride);4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline hydrochloride (1:1);LDN-193189 HCl;LDN-193189 4HCl;LDN-193189 HCl USP/EP/BP;CS-1451
15 prices
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Brand
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Crysdot
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 1000mg
- ManufacturerApexBio Technology
- Product numberA3545
- Product descriptionLDN193189 hydrochloride
- Packaging10mM(in 1mL DMSO)
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60078
- Product descriptionLDN-193189HCl ≥98%
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546252
- Product descriptionLDN193189 HCl >98%
- Packaging5mg
- Price$173.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546252
- Product descriptionLDN193189 HCl >98%
- Packaging25mg
- Price$447.1
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181276
- Product descriptionLDN193189 HCl >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181276
- Product descriptionLDN193189 HCl >98%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181276
- Product descriptionLDN193189 HCl >98%
- Packaging1000mg
- Price$2023
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19396
- Product descriptionLDN-193189 (hydrochloride) ≥98%
- Packaging1mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19396
- Product descriptionLDN-193189 (hydrochloride) ≥98%
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19396
- Product descriptionLDN-193189 (hydrochloride) ≥98%
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19396
- Product descriptionLDN-193189 (hydrochloride) ≥98%
- Packaging25mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM247577
- Product descriptionLDN193189 hydrochloride 98%
- Packaging50mg
- Price$215
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004669
- Product descriptionLDN193189 hydrochloride 98+%
- Packaging50mg
- Price$615
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP480133
- Product descriptionLDN193189 hydrochloride
- Packaging50mg
- Price$825
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP480133
- Product descriptionLDN193189 hydrochloride
- Packaging10mg
- Price$195
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | A3545 | LDN193189 hydrochloride | 10mM(in 1mL DMSO) | $150 | 2021-12-16 | Buy |
| Arctom | CFN60078 | LDN-193189HCl ≥98% | 10mg | $218 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546252 | LDN193189 HCl >98% | 5mg | $173.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546252 | LDN193189 HCl >98% | 25mg | $447.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181276 | LDN193189 HCl >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181276 | LDN193189 HCl >98% | 250mg | $1060.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181276 | LDN193189 HCl >98% | 1000mg | $2023 | 2021-12-16 | Buy |
| Cayman Chemical | 19396 | LDN-193189 (hydrochloride) ≥98% | 1mg | $25 | 2021-12-16 | Buy |
| Cayman Chemical | 19396 | LDN-193189 (hydrochloride) ≥98% | 5mg | $75 | 2021-12-16 | Buy |
| Cayman Chemical | 19396 | LDN-193189 (hydrochloride) ≥98% | 10mg | $138 | 2021-12-16 | Buy |
| Cayman Chemical | 19396 | LDN-193189 (hydrochloride) ≥98% | 25mg | $300 | 2021-12-16 | Buy |
| Chemenu | CM247577 | LDN193189 hydrochloride 98% | 50mg | $215 | 2021-12-16 | Buy |
| Crysdot | CD31004669 | LDN193189 hydrochloride 98+% | 50mg | $615 | 2021-12-16 | Buy |
| TRC | P480133 | LDN193189 hydrochloride | 50mg | $825 | 2021-12-16 | Buy |
| TRC | P480133 | LDN193189 hydrochloride | 10mg | $195 | 2021-12-16 | Buy |
Properties
Melting point :>240°C (dec.)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), DMSO (Very Slightly, Heated)
form :Solid
color :Dark Orange
CAS DataBase Reference :1062368-62-0
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly), DMSO (Very Slightly, Heated)
form :Solid
color :Dark Orange
CAS DataBase Reference :1062368-62-0
Safety Information
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Description
LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are known as activin receptor-like kinases (ALKs), with an IC50 value of 4.9 nM. In in vitro kinase assays, it shows specificity for ALK1, 2, 3, and 6 (IC50s = 0.8, 0.8, 5.3, and 16.7 nM, respectively) over ALK4 and 5 (IC50s = 101 and 350 nM, respectively). LDN-193189 has been used to inhibit BMP type I receptor activity to study the pathogenesis of fibrodysplasia ossificans progressive, a congenital hyperossification disorder, and to examine the role of osteogenesis in prostate tumor metastases in bone.More related product prices
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