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ChemicalBook >> CAS DataBase List >> LIPOXIN B4

LIPOXIN B4

LIPOXIN B4 price.
  • $274 - $980
  • Product name: LIPOXIN B4
  • CAS: 98049-69-5
  • MF: C20H32O5
  • MW: 352.47
  • EINECS:
  • MDL Number:MFCD00870250
  • Synonyms:(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-trihydroxyicosa-6,8,10,12-tetraenoic acid;(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-Trihydroxy-6,8,10,12-icosatetraenoic acid;LXB4;5(S),14(R)-Lipoxin B4;(5S,14R,15S)-5,14,15-Trihydroxy-(6E,8Z,10E,12E)-eicosatetraenoic acid;5(S), 14(R), 15(S)-TRIHYDROXYEICOSA-6E,8Z,10E,12E-TETRAENOIC ACID;LIPOXIN B4;UXVRTOKOJOMENI-WLPVFMORSA-N
7 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 25μg
  • 50μg
  • 100μg
  • 5MG
  • 48Tests
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0007844
  • Product description(5S,14R,15S)-5,14,15-TRIHYDROXY-(6E,8Z,10E,12E)-EICOSATETRAENOIC ACID 95.00%
  • Packaging5MG
  • Price$502.12
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number90420
  • Product descriptionLipoxin B4 ≥95%
  • Packaging25μg
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number90420
  • Product descriptionLipoxin B4 ≥95%
  • Packaging50μg
  • Price$519
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number90420
  • Product descriptionLipoxin B4 ≥95%
  • Packaging100μg
  • Price$980
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL468770
  • Product description5(S),14(R)-LipoxinB4
  • Packaging25μg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberL468770
  • Product description5(S),14(R)-LipoxinB4
  • Packaging50μg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number396443
  • Product descriptionLXB4
  • Packaging48Tests
  • Price$588
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation CCH0007844 (5S,14R,15S)-5,14,15-TRIHYDROXY-(6E,8Z,10E,12E)-EICOSATETRAENOIC ACID 95.00% 5MG $502.12 2021-12-16 Buy
Cayman Chemical 90420 Lipoxin B4 ≥95% 25μg $274 2024-03-01 Buy
Cayman Chemical 90420 Lipoxin B4 ≥95% 50μg $519 2024-03-01 Buy
Cayman Chemical 90420 Lipoxin B4 ≥95% 100μg $980 2024-03-01 Buy
TRC L468770 5(S),14(R)-LipoxinB4 25μg $375 2021-12-16 Buy
TRC L468770 5(S),14(R)-LipoxinB4 50μg $600 2021-12-16 Buy
Usbiological 396443 LXB4 48Tests $588 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :DMF: >50 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Lipoxins are a series of anti-inflammatory lipid mediators whose brief appearance generally signals the resolution of inflammation. Lipoxin A4 (LXA4) is a potent inhibitor of leukotriene (LT)-triggered polymorphonuclear neutrophil (PMN)-endothelial cell interaction and also blocks PMN migration stimulated by LTB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 10-7 M, LXB4 inhibits PMN migration stimulated by LTB4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 X 10-10 M.

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