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ChemicalBook >> CAS DataBase List >> LM22B-10

LM22B-10

LM22B-10 price.
  • $54 - $2200
  • Product name: LM22B-10
  • CAS: 342777-54-2
  • MF: C27H33ClN2O4
  • MW: 485.01
  • EINECS:
  • MDL Number:MFCD00483554
  • Synonyms:LM22B-10;2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL;2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol;Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-;inhibit,Trk Receptor,Akt,LM-22B-10,LM22B-10,LM22B 10,Tropomyosin related kinase receptor,ERK,PKB,Inhibitor,Protein kinase B,Extracellular signal regulated kinases;2,2',2'',2'''-((((4-Chlorophenyl)methylene)bis(4,1-phenylene))bis(azanetriyl))tetrakis(ethan-1-ol)
Price20 Properties Safety Information Description
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Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 2mg
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  • 10
  • 1mg
  • 50
  • 5mg
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  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4763CC
  • Product description2-[4-[[4-[Bis(2-hydroxyethyl)amino]phenyl]-(4-chlorophenyl)methyl]-N-(2-hydroxyethyl)anilino]ethanol
  • Packaging10mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29037
  • Product descriptionLM22B-10
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29037
  • Product descriptionLM22B-10
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29037
  • Product descriptionLM22B-10
  • Packaging25mg
  • Price$365
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7663
  • Product descriptionLM22B-10 98.60%
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7663
  • Product descriptionLM22B-10 98.60%
  • Packaging100mg
  • Price$1920
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging1mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging2mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging5mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging10mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging25mg
  • Price$561
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging50mg
  • Price$865
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004984
  • Product descriptionLM22B-10 99%
  • Packaging100mg
  • Price$1730
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10758
  • Product descriptionLM22B-10 >98%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10758
  • Product descriptionLM22B-10 >98%
  • Packaging1g
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2461
  • Product descriptionLM22B-10 ≥98% (HPLC)
  • Packaging5mg
  • Price$102
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4763CC 2-[4-[[4-[Bis(2-hydroxyethyl)amino]phenyl]-(4-chlorophenyl)methyl]-N-(2-hydroxyethyl)anilino]ethanol 10mg $282 2021-12-16 Buy
Cayman Chemical 29037 LM22B-10 5mg $93 2024-03-01 Buy
Cayman Chemical 29037 LM22B-10 10mg $166 2024-03-01 Buy
Cayman Chemical 29037 LM22B-10 25mg $365 2024-03-01 Buy
ChemScene CS-7663 LM22B-10 98.60% 10mg $300 2021-12-16 Buy
ChemScene CS-7663 LM22B-10 98.60% 100mg $1920 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 1mg $54 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 2mg $92 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 5mg $140 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 10mg $235 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 25mg $561 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 50mg $865 2021-12-16 Buy
Crysdot CD31004984 LM22B-10 99% 100mg $1730 2021-12-16 Buy
DC Chemicals DC10758 LM22B-10 >98% 100mg $650 2021-12-16 Buy
DC Chemicals DC10758 LM22B-10 >98% 1g $2200 2021-12-16 Buy
Sigma-Aldrich SML2461 LM22B-10 ≥98% (HPLC) 5mg $102 2024-03-01 Buy
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Properties

Boiling point :718.9±60.0 °C(Predicted)
Density :1.287±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form :A crystalline solid
pka :14.00±0.10(Predicted)
color :Light green to green

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LM22B-10 is a TrkB and TrkC agonist. Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro. Exhibits no significant activity in a screen of 57 other receptors and transporters. Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively. Active in vivo and brain penetrant.

Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
InvivoChem
TargetMol Chemicals Inc.
LEAPCHEM CO., LTD.
Aladdin Scientific MedChemexpress LLC Shanghai Lollane Biological Technology Co.,Ltd. Shanghai Beckham Medical Technology Co., Ltd Shanghai EFE Biological Technology Co., Ltd.