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ChemicalBook >> CAS DataBase List >> LY2940680

LY2940680

LY2940680 price.
  • $55 - $5541
  • Product name: LY2940680
  • CAS: 1258861-20-9
  • MF: C26H24F4N6O
  • MW: 512.5
  • EINECS:
  • MDL Number:MFCD21609264
  • Synonyms:Taladegib (LY2940680);4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide LY 2940680;LY2940680;LY2940680 (Taladegib);Taladegib;Taladegib hydrochloride;4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluo;4-Fluoro-N-methyl-N-[1-[4-(1-methyl-1H-pyrazol-5-yl)-1-phthalazinyl]-4-piperidinyl]-2-(trifluoromethyl)benzamide
26 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 1MG
  • 2.5mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1000mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7613
  • Product description4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide
  • Packaging25mg
  • Price$254
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013718
  • Product description4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00%
  • Packaging1MG
  • Price$173.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013718
  • Product description4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00%
  • Packaging5MG
  • Price$498.43
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging50mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8651
  • Product descriptionLY2940680
  • Packaging200mg
  • Price$1386
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180965
  • Product descriptionLY-2940680 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180965
  • Product descriptionLY-2940680 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180965
  • Product descriptionLY-2940680 >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16264
  • Product descriptionLY2940680 ≥98%
  • Packaging1mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16264
  • Product descriptionLY2940680 ≥98%
  • Packaging5mg
  • Price$162
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16264
  • Product descriptionLY2940680 ≥98%
  • Packaging10mg
  • Price$292
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM181283
  • Product description4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide 98%
  • Packaging100mg
  • Price$552
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0459
  • Product descriptionTaladegib 99.93%
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0459
  • Product descriptionTaladegib 99.93%
  • Packaging10mg
  • Price$175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7613 4-fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide 25mg $254 2021-12-16 Buy
American Custom Chemicals Corporation API0013718 4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00% 1MG $173.25 2021-12-16 Buy
American Custom Chemicals Corporation API0013718 4-FLUORO-N-METHYL-N-[1-[4-(1-METHYL-1H-PYRAZOL-5-YL)-1-PHTHALAZINYL]-4-PIPERIDINYL]-2-(TRIFLUOROMETHYL)BENZAMIDE 95.00% 5MG $498.43 2021-12-16 Buy
ApexBio Technology A8651 LY2940680 5mg $120 2021-12-16 Buy
ApexBio Technology A8651 LY2940680 10mg $220 2021-12-16 Buy
ApexBio Technology A8651 LY2940680 50mg $470 2021-12-16 Buy
ApexBio Technology A8651 LY2940680 200mg $1386 2021-12-16 Buy
Biorbyt Ltd orb180965 LY-2940680 >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb180965 LY-2940680 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb180965 LY-2940680 >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 16264 LY2940680 ≥98% 1mg $61 2024-03-01 Buy
Cayman Chemical 16264 LY2940680 ≥98% 5mg $162 2024-03-01 Buy
Cayman Chemical 16264 LY2940680 ≥98% 10mg $292 2024-03-01 Buy
Chemenu CM181283 4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide 98% 100mg $552 2021-12-16 Buy
ChemScene CS-0459 Taladegib 99.93% 5mg $110 2021-12-16 Buy
ChemScene CS-0459 Taladegib 99.93% 10mg $175 2021-12-16 Buy

Properties

Boiling point :703.5±60.0 °C(Predicted)
Density :1.39
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥5.2 mg/mL in EtOH with ultrasonic; ≥51.3 mg/mL in DMSO with gentle warming and ultrasonic
form :crystalline solid
pka :7.94±0.30(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…

Description

Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors. LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro). The potential anticancer activity of LY2940680 is currently under clinical investigation.

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