LY3214996
|
- $57 - $2100
- Product name: LY3214996
- CAS: 1951483-29-6
- MF: C22H27N7O2S
- MW: 453.56
- EINECS:-0
- MDL Number:MFCD31544324
- Synonyms:LY3214996;6,6-dimethyl-2-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-5-(2-morpholinoethyl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-4-one;CS-2495;4H-Thieno[2,3-c]pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-[2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimidinyl]-5-[2-(4-morpholinyl)ethyl]-;Temuterkib;Temuterkib (LY3214996);LY-3214996,LY 3214996,inhibit,Extracellular signal regulated kinases,Temuterkib,Inhibitor,ERK;LY-3214996 (LY3214996)
12 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number5975EG
- Product descriptionCID121408882
- Packaging5mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27936
- Product descriptionLY3214996
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27936
- Product descriptionLY3214996
- Packaging5mg
- Price$233
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27936
- Product descriptionLY3214996
- Packaging10mg
- Price$437
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27936
- Product descriptionLY3214996
- Packaging25mg
- Price$1026
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-6974
- Product descriptionLY3214996 99.54%
- Packaging1mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6974
- Product descriptionLY3214996 99.54%
- Packaging5mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6974
- Product descriptionLY3214996 99.54%
- Packaging10mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6974
- Product descriptionLY3214996 99.54%
- Packaging50mg
- Price$1300
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6974
- Product descriptionLY3214996 99.54%
- Packaging100mg
- Price$2100
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10640
- Product descriptionLY3214996 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10640
- Product descriptionLY3214996 >98%
- Packaging250mg
- Price$1300
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5975EG | CID121408882 | 5mg | $357 | 2021-12-16 | Buy |
| Cayman Chemical | 27936 | LY3214996 | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 27936 | LY3214996 | 5mg | $233 | 2024-03-01 | Buy |
| Cayman Chemical | 27936 | LY3214996 | 10mg | $437 | 2024-03-01 | Buy |
| Cayman Chemical | 27936 | LY3214996 | 25mg | $1026 | 2024-03-01 | Buy |
| ChemScene | CS-6974 | LY3214996 99.54% | 1mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-6974 | LY3214996 99.54% | 5mg | $240 | 2021-12-16 | Buy |
| ChemScene | CS-6974 | LY3214996 99.54% | 10mg | $380 | 2021-12-16 | Buy |
| ChemScene | CS-6974 | LY3214996 99.54% | 50mg | $1300 | 2021-12-16 | Buy |
| ChemScene | CS-6974 | LY3214996 99.54% | 100mg | $2100 | 2021-12-16 | Buy |
| DC Chemicals | DC10640 | LY3214996 >98% | 100mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC10640 | LY3214996 >98% | 250mg | $1300 | 2021-12-16 | Buy |
Properties
Boiling point :711.5±70.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:23.5(Max Conc. mg/mL);51.81(Max Conc. mM)
Ethanol:16.0(Max Conc. mg/mL);35.28(Max Conc. mM) form :A crystalline solid
pka :6.58±0.10(Predicted)
color :White to yellow
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:23.5(Max Conc. mg/mL);51.81(Max Conc. mM)
Ethanol:16.0(Max Conc. mg/mL);35.28(Max Conc. mM) form :A crystalline solid
pka :6.58±0.10(Predicted)
color :White to yellow
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
LY3214996 is an inhibitor of ERK1 and ERK2 (IC50 = 5 nM for both). It inhibits cell proliferation of tumor cells in vitro, including those expressing B-RAF, N-Ras, or K-Ras mutations. LY3214996 inhibits tumor growth in B-RAF or N-Ras mutant melanoma, B-RAF or K-Ras mutant colorectal, lung, and pancreatic cancer mouse xenograft models, as well as patient-derived xenograft (PDX) mouse models.More related product prices
LY2955303 LY 294002 HYDROCHLORIDE 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol LY-3177833 LY-364947 LY2409881 trihydrochloride LY 2784544 Etalocib LY2228820 LY-2562175 LY2828360 LY 334370 HYDROCHLORIDERelated product price
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Jinan Carbotang Biotech Co.,Ltd.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nanjing Doge Biomedical Technology Co., Ltd
TargetMol Chemicals Inc.
Chemtour Biotech Co., Ltd
Wuhan Topule Biopharmaceutical Co., Ltd
