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ChemicalBook >> CAS DataBase List >> Liproxstatin-1

Liproxstatin-1

Liproxstatin-1 price.
  • $59 - $1787
  • Product name: Liproxstatin-1
  • CAS: 950455-15-9
  • MF: C19H21ClN4
  • MW: 340.85
  • EINECS:
  • MDL Number:MFCD14948691
  • Synonyms:Liproxstatin-1;N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine;N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine;LIPROXSTATIN-1;LIPROXSTATIN1;CS-1656;N-[(3-chlorophenyl)methyl]spiro[4H-quinoxaline-3,4'-piperidine]-2-amine;Liproxstatin-1 USP/EP/BP;N-[(3-chlorophenyl)methyl]-1'H-spiro[piperidine-4,2'-quinoxaline]-3'-amine
Price30 Properties Safety Information Description
30 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 2mg
  • 10mg
  • 5mg
  • 10mM(in 1mL DMSO)
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4857EM
  • Product descriptionLiproxstatin-1
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4857EM
  • Product descriptionLiproxstatin-1
  • Packaging50mg
  • Price$758
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging2mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging5mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging25mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging50mg
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging100mg
  • Price$478
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging250mg
  • Price$716
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA120662
  • Product descriptionN-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+%
  • Packaging1g
  • Price$1787
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4987
  • Product descriptionLiproxstatin-1
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8221
  • Product descriptionLiproxstatin-1HCl
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4987
  • Product descriptionLiproxstatin-1
  • Packaging10mM(in 1mL DMSO)
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4987
  • Product descriptionLiproxstatin-1
  • Packaging25mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB8221
  • Product descriptionLiproxstatin-1HCl
  • Packaging25mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4987
  • Product descriptionLiproxstatin-1
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4857EM Liproxstatin-1 5mg $201 2021-12-16 Buy
AK Scientific 4857EM Liproxstatin-1 50mg $758 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 2mg $127 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 5mg $166 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 10mg $216 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 25mg $282 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 50mg $367 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 100mg $478 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 250mg $716 2021-12-16 Buy
Ambeed A120662 N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine 98+% 1g $1787 2021-12-16 Buy
ApexBio Technology B4987 Liproxstatin-1 5mg $105 2021-12-16 Buy
ApexBio Technology B8221 Liproxstatin-1HCl 5mg $105 2021-12-16 Buy
ApexBio Technology B4987 Liproxstatin-1 10mM(in 1mL DMSO) $110 2021-12-16 Buy
ApexBio Technology B4987 Liproxstatin-1 25mg $340 2021-12-16 Buy
ApexBio Technology B8221 Liproxstatin-1HCl 25mg $340 2021-12-16 Buy
ApexBio Technology B4987 Liproxstatin-1 100mg $700 2021-12-16 Buy
Next Last

Properties

Boiling point :581.4±50.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (15 mg/ml)
form :powder
pka :9.45±0.40(Predicted)
color :white to light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Ferroptosis is a regulated, non-apoptotic form of cell death involving the production of iron-dependent reactive oxygen species (ROS). Glutathione peroxidase 4 (Gpx4) is an essential regulator of ferroptotic cell death, playing a critical role in preventing ROS-induced lipid peroxidation. Liproxstatin-1 is an inhibitor of ferroptosis induced in mouse embryonic fibroblasts (MEFs) by Gpx4 deletion (IC50 = 22 nM). It does not interfere with apoptosis, necroptosis, or necrosis. Liproxstatin-1 also blocks ferroptosis induced by specific ferroptosis inducers, including the glutathioine-depleting agents BSO and erastin and the Gpx4 inhibitor RSL3. It is effective in vivo when administered intraperitoneally, suppressing ferroptosis in Gpx4-/- mice and in a mouse model of ischemia/reperfusion-induced liver injury.

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Suppliers and manufacturers

career henan chemical co
N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine
$1.00 /1KG
N-(3-Chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine CAS:950455-15-9
Shaanxi Dideu Medichem Co. Ltd
Liproxstatin-1
$0.00 /5mg
Liproxstatin-1 CAS:950455-15-9
TargetMol Chemicals Inc.
Liproxstatin-1
$48.00 /2mg
Liproxstatin-1 CAS:950455-15-9
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei xin bonus chemical co. LTD
BOC Sciences
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem