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ChemicalBook >> CAS DataBase List >> MBX2982

MBX2982

MBX2982 price.
  • $106 - $3564
  • Product name: MBX2982
  • CAS: 1037792-44-1
  • MF: C22H24N8OS
  • MW: 448.54
  • EINECS:
  • MDL Number:MFCD22628771
  • Synonyms:MBX2982;5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine;MBX2982 / MBX-2982;5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine MBX-2982;pyrimidine, 5-ethyl-2-[4-[4-[[4-(1h-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-;2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole;MBX-2982, >=98%;SAR-260093
19 prices
Selected condition:
Brand
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerApexBio Technology
  • Product numberA3587
  • Product descriptionMBX-2982
  • Packaging5mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3587
  • Product descriptionMBX-2982
  • Packaging10mg
  • Price$442
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3587
  • Product descriptionMBX-2982
  • Packaging50mg
  • Price$1421
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181053
  • Product descriptionMBX-2982 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181053
  • Product descriptionMBX-2982 >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181053
  • Product descriptionMBX-2982 >98%
  • Packaging1000mg
  • Price$2839
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22206
  • Product descriptionMBX-2982 ≥98%
  • Packaging5mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22206
  • Product descriptionMBX-2982 ≥98%
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22206
  • Product descriptionMBX-2982 ≥98%
  • Packaging25mg
  • Price$606
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22206
  • Product descriptionMBX-2982 ≥98%
  • Packaging50mg
  • Price$844
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0745
  • Product descriptionMBX-2982 99.54%
  • Packaging5mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0745
  • Product descriptionMBX-2982 99.54%
  • Packaging10mg
  • Price$362
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0745
  • Product descriptionMBX-2982 99.54%
  • Packaging50mg
  • Price$1164
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004757
  • Product descriptionMBX-2982 98+%
  • Packaging5mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004757
  • Product descriptionMBX-2982 98+%
  • Packaging50mg
  • Price$631
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7193
  • Product descriptionMBX-2982 >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology A3587 MBX-2982 5mg $238 2021-12-16 Buy
ApexBio Technology A3587 MBX-2982 10mg $442 2021-12-16 Buy
ApexBio Technology A3587 MBX-2982 50mg $1421 2021-12-16 Buy
Biorbyt Ltd orb181053 MBX-2982 >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb181053 MBX-2982 >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb181053 MBX-2982 >98% 1000mg $2839 2021-12-16 Buy
Cayman Chemical 22206 MBX-2982 ≥98% 5mg $153 2024-03-01 Buy
Cayman Chemical 22206 MBX-2982 ≥98% 10mg $275 2024-03-01 Buy
Cayman Chemical 22206 MBX-2982 ≥98% 25mg $606 2024-03-01 Buy
Cayman Chemical 22206 MBX-2982 ≥98% 50mg $844 2024-03-01 Buy
ChemScene CS-0745 MBX-2982 99.54% 5mg $196 2021-12-16 Buy
ChemScene CS-0745 MBX-2982 99.54% 10mg $362 2021-12-16 Buy
ChemScene CS-0745 MBX-2982 99.54% 50mg $1164 2021-12-16 Buy
Crysdot CD31004757 MBX-2982 98+% 5mg $106 2021-12-16 Buy
Crysdot CD31004757 MBX-2982 98+% 50mg $631 2021-12-16 Buy
DC Chemicals DC7193 MBX-2982 >98% 100mg $550 2021-12-16 Buy

Properties

Boiling point :683.6±65.0 °C(Predicted)
Density :1.42
storage temp. :Store at -20°C
solubility :DMSO : 50 mg/mL (111.47 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :Powder
pka :5.39±0.42(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits hepatic lipid accumulation in wild-type, but not GPR119 knockout, mice fed a high-fat diet. It also increases plasma levels of glucagon-like peptide 1 (GLP-1; ) in mice when administered at a dose of 10 mg/kg prior to, and to a greater extent following, glucose administration. MBX-2982 increases glucokinase activity in an enzyme assay with an EC50 value of 45.11 μM.