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ChemicalBook >> CAS DataBase List >> MC-MMAF

MC-MMAF

MC-MMAF price.
  • $140 - $25750
  • Product name: MC-MMAF
  • CAS: 863971-19-1
  • MF: C49H76N6O11
  • MW: 925.16
  • EINECS:
  • MDL Number:MFCD25976741
  • Synonyms:Mafodotin;MaleiMidocaproyl MonoMethylauristatin F;McMMAF;Mc-MMAF;SGD 1269;(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic aci;(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid;SGD-1269(MCMMAF)
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • Ambeed
  • BroadPharm
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • ManufacturerAmbeed
  • Product numberA107026
  • Product description(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+%
  • Packaging1mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107026
  • Product description(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+%
  • Packaging5mg
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107026
  • Product description(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+%
  • Packaging10mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107026
  • Product description(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+%
  • Packaging25mg
  • Price$787
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107026
  • Product description(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+%
  • Packaging50mg
  • Price$1177
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA107026
  • Product description(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+%
  • Packaging100mg
  • Price$1766
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-23981
  • Product descriptionMC-MMAF 98%
  • Packaging1mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-23981
  • Product descriptionMC-MMAF 98%
  • Packaging10mg
  • Price$2250
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM255394
  • Product descriptionMcMMAF 98%
  • Packaging10mg
  • Price$982
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD35000017
  • Product descriptionMcMMAF 98+%
  • Packaging5mg
  • Price$1113
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD35000017
  • Product descriptionMcMMAF 98+%
  • Packaging10mg
  • Price$1704
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC31389
  • Product descriptionSGD-1269(MCMMAF)
  • Packaging100mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC31389
  • Product descriptionSGD-1269(MCMMAF)
  • Packaging250mg
  • Price$2100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC31389
  • Product descriptionSGD-1269(MCMMAF)
  • Packaging500mg
  • Price$3800
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number52051
  • Product descriptionMafodotin
  • Packaging25mg
  • Price$19750
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number52051
  • Product descriptionMafodotin
  • Packaging100mg
  • Price$25750
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A107026 (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+% 1mg $140 2021-12-16 Buy
Ambeed A107026 (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+% 5mg $314 2021-12-16 Buy
Ambeed A107026 (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+% 10mg $470 2021-12-16 Buy
Ambeed A107026 (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+% 25mg $787 2021-12-16 Buy
Ambeed A107026 (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+% 50mg $1177 2021-12-16 Buy
Ambeed A107026 (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoicacid 98+% 100mg $1766 2021-12-16 Buy
BroadPharm BP-23981 MC-MMAF 98% 1mg $380 2021-12-16 Buy
BroadPharm BP-23981 MC-MMAF 98% 10mg $2250 2021-12-16 Buy
Chemenu CM255394 McMMAF 98% 10mg $982 2021-12-16 Buy
Crysdot CD35000017 McMMAF 98+% 5mg $1113 2021-12-16 Buy
Crysdot CD35000017 McMMAF 98+% 10mg $1704 2021-12-16 Buy
DC Chemicals DC31389 SGD-1269(MCMMAF) 100mg $1200 2021-12-16 Buy
DC Chemicals DC31389 SGD-1269(MCMMAF) 250mg $2100 2021-12-16 Buy
DC Chemicals DC31389 SGD-1269(MCMMAF) 500mg $3800 2021-12-16 Buy
Medical Isotopes, Inc. 52051 Mafodotin 25mg $19750 2021-12-16 Buy
Medical Isotopes, Inc. 52051 Mafodotin 100mg $25750 2021-12-16 Buy
Next Last

Properties

Boiling point :1052.0±65.0 °C(Predicted)
Density :1.167±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO : ≥ 100 mg/mL (108.09 mM)
pka :3.56±0.10(Predicted)
form :Solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P350 IF ON SKIN: Gently wash with plenty of soap and water.

Description

MC-MMAF is an antibody that binds to the epidermal growth factor receptor (EGFR) on tumor cells and inhibits the proliferation of tumor cells by blocking the binding of epidermal growth factor. MC-MMAF has been shown to be an effective treatment for a variety of cancers, including breast cancer, lung cancer, head and neck cancer, and colorectal cancer. It is also being studied as a potential treatment for autoimmune diseases such as rheumatoid arthritis and psoriasis. MC-MMAF has been shown to improve prognosis in patients with glomerular filtration rate (GFR) less than 30 mL/min per 1.73 m2.

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