MI-192
|
- $44 - $564
- Product name: MI-192
- CAS: 1415340-63-4
- MF: C24H21N3O2
- MW: 383.44
- EINECS:
- MDL Number:
- Synonyms:MI-192;MI-192 hydrochloride;N-(2-Aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]benzamide;Benzamide, N-(2-aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]-;MI-192 hydrochloride, HDAC2/3 inhibitor
8 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerAK Scientific
- Product number2177DN
- Product descriptionChembl4294949
- Packaging10mg
- Price$478
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5851
- Product descriptionMI-192
- Packaging5mg
- Price$219
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5851
- Product descriptionMI-192
- Packaging10mg
- Price$389
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18288
- Product descriptionMI-192 ≥98%
- Packaging10mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18288
- Product descriptionMI-192 ≥98%
- Packaging5mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18288
- Product descriptionMI-192 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1451
- Product descriptionMI192 hydrochloride ≥98% (HPLC)
- Packaging5mg
- Price$117
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1451
- Product descriptionMI192 hydrochloride ≥98% (HPLC)
- Packaging25mg
- Price$564
- Updated2023-01-07
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2177DN | Chembl4294949 | 10mg | $478 | 2021-12-16 | Buy |
| ApexBio Technology | C5851 | MI-192 | 5mg | $219 | 2021-12-16 | Buy |
| ApexBio Technology | C5851 | MI-192 | 10mg | $389 | 2021-12-16 | Buy |
| Cayman Chemical | 18288 | MI-192 ≥98% | 10mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 18288 | MI-192 ≥98% | 5mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 18288 | MI-192 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1451 | MI192 hydrochloride ≥98% (HPLC) | 5mg | $117 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1451 | MI192 hydrochloride ≥98% (HPLC) | 25mg | $564 | 2023-01-07 | Buy |
Properties
Boiling point :565.0±50.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≤5mg/ml in DMSO;1mg/ml in dimethyl formamide
pka :13.08±0.70(Predicted)
form :powder
color :white to light brown
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≤5mg/ml in DMSO;1mg/ml in dimethyl formamide
pka :13.08±0.70(Predicted)
form :powder
color :white to light brown
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
MI-192 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC2 (IC50 = 30 nM) and HDAC3 (IC50 = 16 nM) over HDAC1, 4, 6, 7, and 8 (IC50s = 4.8, 5, >10, 4.1, and >10 μM, respectively). At 0.1-0.4 μM, it induces differentiation and promotes apoptosis of acute myeloid leukemic cell lines U937, HL60, and Kasumi-1.Suppliers and manufacturers
Career Henan Chemica Co
Aladdin Scientific
Sigma-Aldrich
Shanghai EFE Biological Technology Co., Ltd.
Angel Pharmatech, Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
TargetMol Chemicals Inc.
Nantong QuanYi Biotechnology Co., Ltd
RD International Technology Co., Limited