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ChemicalBook >> CAS DataBase List >> MK-886

MK-886

MK-886 price.
  • $32 - $2000
  • Product name: MK-886
  • CAS: 118427-55-7
  • MF: C27H33ClNNaO2S
  • MW: 494.06
  • EINECS:
  • MDL Number:MFCD11045945
  • Synonyms:3-[TERT-BUTYLTHIO-1-(4-CHLOROBENZYL)-5-ISOPROPYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPIONIC ACID, SODIUM SALT;1-[(4-CHLOROPHENYL)METHYL]-3-[(1,1-DIMETHYLETHYL)THIO]-ALPHA,ALPHA-DIMETHYL-5-(1-METHYLETHYL)-1H-INDOLE-2-PROPANOIC ACID, SODIUM SALT;3-[3-TERT-BUTYLTHIO-1-(4-CHLOROBENZYL)-5-ISOPROPYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPIONIC ACID, SODIUM;3-[1-(P-CHLOROBENZYL)-5-(ISOPROPYL)-3-T-BUTYLTHIOINDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID, NA;3-[1-(p-Chlorobenzyl)-5-(isopropyl)-3-t-butylthioindol-2-yl]-2,2-dimethylpropanoic acid,sodium;3-[3-tert-butylthio-1-(4-chlorobenzyl)-5-isopropyl-1h-indol-2-yl]-2,2-dimethylpropionic acid, sodium salt hydrate;mk-886 sodium hydrate;3-[3-tert-Butylthio-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethylpropionic acid, hydrate sodium salt
22 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 5MG
  • 2mg
  • 10
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000849
  • Product descriptionMK-886 SODIUM SALT HYDRATE 95.00%
  • Packaging5MG
  • Price$707.04
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000849
  • Product descriptionMK-886 SODIUM SALT HYDRATE 95.00%
  • Packaging25MG
  • Price$999.92
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26028
  • Product descriptionMK 886 sodium salt
  • Packaging1mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26028
  • Product descriptionMK 886 sodium salt
  • Packaging2mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBM166037
  • Product descriptionMK 886
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26028
  • Product descriptionMK 886 sodium salt
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26028
  • Product descriptionMK 886 sodium salt
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBM166037
  • Product descriptionMK 886
  • Packaging50mg
  • Price$472.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFM26028
  • Product descriptionMK 886 sodium salt
  • Packaging25mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10133
  • Product descriptionMK-886 (sodium salt) ≥99%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10133
  • Product descriptionMK-886 (sodium salt) ≥99%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10133
  • Product descriptionMK-886 (sodium salt) ≥99%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10133
  • Product descriptionMK-886 (sodium salt) ≥99%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7464
  • Product descriptionMK-886(sodiumsalt) >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7464
  • Product descriptionMK-886(sodiumsalt) >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number47749
  • Product descriptionMK-886SodiumSalt
  • Packaging10mg
  • Price$625
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0000849 MK-886 SODIUM SALT HYDRATE 95.00% 5MG $707.04 2021-12-16 Buy
American Custom Chemicals Corporation INB0000849 MK-886 SODIUM SALT HYDRATE 95.00% 25MG $999.92 2021-12-16 Buy
Biosynth Carbosynth FM26028 MK 886 sodium salt 1mg $70 2021-12-16 Buy
Biosynth Carbosynth FM26028 MK 886 sodium salt 2mg $100 2021-12-16 Buy
Biosynth Carbosynth BM166037 MK 886 10mg $135 2021-12-16 Buy
Biosynth Carbosynth FM26028 MK 886 sodium salt 5mg $150 2021-12-16 Buy
Biosynth Carbosynth FM26028 MK 886 sodium salt 10mg $250 2021-12-16 Buy
Biosynth Carbosynth BM166037 MK 886 50mg $472.5 2021-12-16 Buy
Biosynth Carbosynth FM26028 MK 886 sodium salt 25mg $480 2021-12-16 Buy
Cayman Chemical 10133 MK-886 (sodium salt) ≥99% 1mg $32 2024-03-01 Buy
Cayman Chemical 10133 MK-886 (sodium salt) ≥99% 5mg $93 2024-03-01 Buy
Cayman Chemical 10133 MK-886 (sodium salt) ≥99% 10mg $153 2024-03-01 Buy
Cayman Chemical 10133 MK-886 (sodium salt) ≥99% 25mg $343 2024-03-01 Buy
DC Chemicals DC7464 MK-886(sodiumsalt) >98% 100mg $550 2021-12-16 Buy
DC Chemicals DC7464 MK-886(sodiumsalt) >98% 1g $1600 2021-12-16 Buy
Medical Isotopes, Inc. 47749 MK-886SodiumSalt 10mg $625 2021-12-16 Buy

Properties

Melting point :275-278°C
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Arachidonic acid and selected other polyunsaturated fatty acids are stereoselectively oxygenated at carbon 5 by the non-heme iron containing enzyme 5-lipoxygenase (5-LO). The intervention of a second protein, 5-LO-activating protein (FLAP), is required before 5-LO can become catalytically active. MK-886 binds to FLAP with high-affinity and prevents 5-LO activation. MK-886 inhibits leukotriene biosynthesis in leukocytes with an IC50 of 2.5 nM. In human whole blood, leukotriene biosynthesis is inhibited by MK-886 with an IC50 of 1.1 μM.

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