MK-886
- $32 - $2000
- Product name: MK-886
- CAS: 118427-55-7
- MF: C27H33ClNNaO2S
- MW: 494.06
- EINECS:
- MDL Number:MFCD11045945
- Synonyms:3-[TERT-BUTYLTHIO-1-(4-CHLOROBENZYL)-5-ISOPROPYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPIONIC ACID, SODIUM SALT;1-[(4-CHLOROPHENYL)METHYL]-3-[(1,1-DIMETHYLETHYL)THIO]-ALPHA,ALPHA-DIMETHYL-5-(1-METHYLETHYL)-1H-INDOLE-2-PROPANOIC ACID, SODIUM SALT;3-[3-TERT-BUTYLTHIO-1-(4-CHLOROBENZYL)-5-ISOPROPYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPIONIC ACID, SODIUM;3-[1-(P-CHLOROBENZYL)-5-(ISOPROPYL)-3-T-BUTYLTHIOINDOL-2-YL]-2,2-DIMETHYLPROPANOIC ACID, NA;3-[1-(p-Chlorobenzyl)-5-(isopropyl)-3-t-butylthioindol-2-yl]-2,2-dimethylpropanoic acid,sodium;3-[3-tert-butylthio-1-(4-chlorobenzyl)-5-isopropyl-1h-indol-2-yl]-2,2-dimethylpropionic acid, sodium salt hydrate;mk-886 sodium hydrate;3-[3-tert-Butylthio-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethylpropionic acid, hydrate sodium salt
22 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- DC Chemicals
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 2mg
- 10
- 10mg
- 25MG
- 50mg
- 100mg
- 1g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000849
- Product descriptionMK-886 SODIUM SALT HYDRATE 95.00%
- Packaging5MG
- Price$707.04
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000849
- Product descriptionMK-886 SODIUM SALT HYDRATE 95.00%
- Packaging25MG
- Price$999.92
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26028
- Product descriptionMK 886 sodium salt
- Packaging1mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26028
- Product descriptionMK 886 sodium salt
- Packaging2mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM166037
- Product descriptionMK 886
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26028
- Product descriptionMK 886 sodium salt
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26028
- Product descriptionMK 886 sodium salt
- Packaging10mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBM166037
- Product descriptionMK 886
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM26028
- Product descriptionMK 886 sodium salt
- Packaging25mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10133
- Product descriptionMK-886 (sodium salt) ≥99%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10133
- Product descriptionMK-886 (sodium salt) ≥99%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10133
- Product descriptionMK-886 (sodium salt) ≥99%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10133
- Product descriptionMK-886 (sodium salt) ≥99%
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC7464
- Product descriptionMK-886(sodiumsalt) >98%
- Packaging100mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7464
- Product descriptionMK-886(sodiumsalt) >98%
- Packaging1g
- Price$1600
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number47749
- Product descriptionMK-886SodiumSalt
- Packaging10mg
- Price$625
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | INB0000849 | MK-886 SODIUM SALT HYDRATE 95.00% | 5MG | $707.04 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000849 | MK-886 SODIUM SALT HYDRATE 95.00% | 25MG | $999.92 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26028 | MK 886 sodium salt | 1mg | $70 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26028 | MK 886 sodium salt | 2mg | $100 | 2021-12-16 | Buy |
Biosynth Carbosynth | BM166037 | MK 886 | 10mg | $135 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26028 | MK 886 sodium salt | 5mg | $150 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26028 | MK 886 sodium salt | 10mg | $250 | 2021-12-16 | Buy |
Biosynth Carbosynth | BM166037 | MK 886 | 50mg | $472.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FM26028 | MK 886 sodium salt | 25mg | $480 | 2021-12-16 | Buy |
Cayman Chemical | 10133 | MK-886 (sodium salt) ≥99% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 10133 | MK-886 (sodium salt) ≥99% | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 10133 | MK-886 (sodium salt) ≥99% | 10mg | $153 | 2024-03-01 | Buy |
Cayman Chemical | 10133 | MK-886 (sodium salt) ≥99% | 25mg | $343 | 2024-03-01 | Buy |
DC Chemicals | DC7464 | MK-886(sodiumsalt) >98% | 100mg | $550 | 2021-12-16 | Buy |
DC Chemicals | DC7464 | MK-886(sodiumsalt) >98% | 1g | $1600 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 47749 | MK-886SodiumSalt | 10mg | $625 | 2021-12-16 | Buy |
Properties
Melting point :275-278°C
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
Arachidonic acid and selected other polyunsaturated fatty acids are stereoselectively oxygenated at carbon 5 by the non-heme iron containing enzyme 5-lipoxygenase (5-LO). The intervention of a second protein, 5-LO-activating protein (FLAP), is required before 5-LO can become catalytically active. MK-886 binds to FLAP with high-affinity and prevents 5-LO activation. MK-886 inhibits leukotriene biosynthesis in leukocytes with an IC50 of 2.5 nM. In human whole blood, leukotriene biosynthesis is inhibited by MK-886 with an IC50 of 1.1 μM.More related product prices
Related product price
- MK-886
$20-1880
Suppliers and manufacturers
LEAPCHEM CO., LTD.
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chemsky(shanghai)International Co.,Ltd.
Shanghai Hongye Biotechnology Co. Ltd
Shenzhen Polymeri Biochemical Technology Co., Ltd.
BOC Sciences
DC Chemicals
ChemeGen(Shanghai) Biotechnology Co.,Ltd.