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ChemicalBook >> CAS DataBase List >> MONASTROL

MONASTROL

MONASTROL price.
  • $55 - $2395.3
  • Product name: MONASTROL
  • CAS: 329689-23-8
  • MF: C14H16N2O3S
  • MW: 292.35
  • EINECS:200-258-5
  • MDL Number:
  • Synonyms:MONASTROL;Monastrol, >=98%;MONASTROL (Free base);5-PyriMidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(3-hydroxyphenyl)-6-Methyl-2-thioxo-, ethyl ester;6-Methyl-4-(3-hydroxyphenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester;(±)-Monastro;CS-763;Ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
33 prices
Selected condition:
Brand
  • AHH
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 100mg
  • 250mg
  • 1g
  • 50
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25mg
  • 0.05g
  • 50mg
  • ManufacturerAHH
  • Product numberMT-54323
  • Product descriptionMonastrol 98%
  • Packaging0.05g
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67096
  • Product descriptionMonastrol, 98%
  • Packaging5mg
  • Price$250
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA101991
  • Product descriptionDL-Monastrol 98+%
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101991
  • Product descriptionDL-Monastrol 98+%
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101991
  • Product descriptionDL-Monastrol 98+%
  • Packaging25mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA101991
  • Product descriptionDL-Monastrol 98+%
  • Packaging50mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6075
  • Product descriptionMonastrol
  • Packaging10mM(in 1mL DMSO)
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6075
  • Product descriptionMonastrol
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6075
  • Product descriptionMonastrol
  • Packaging50mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546088
  • Product descriptionMonastrol >98%
  • Packaging5mg
  • Price$209.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546088
  • Product descriptionMonastrol >98%
  • Packaging25mg
  • Price$554.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146117
  • Product descriptionMonastrol >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146117
  • Product descriptionMonastrol >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146117
  • Product descriptionMonastrol >98%
  • Packaging1g
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15044
  • Product descriptionMonastrol ≥98%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15044
  • Product descriptionMonastrol ≥98%
  • Packaging5mg
  • Price$104
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-54323 Monastrol 98% 0.05g $430 2021-12-16 Buy
Alfa Aesar J67096 Monastrol, 98% 5mg $250 2023-06-20 Buy
Ambeed A101991 DL-Monastrol 98+% 5mg $65 2021-12-16 Buy
Ambeed A101991 DL-Monastrol 98+% 10mg $85 2021-12-16 Buy
Ambeed A101991 DL-Monastrol 98+% 25mg $111 2021-12-16 Buy
Ambeed A101991 DL-Monastrol 98+% 50mg $145 2021-12-16 Buy
ApexBio Technology B6075 Monastrol 10mM(in 1mL DMSO) $72 2021-12-16 Buy
ApexBio Technology B6075 Monastrol 10mg $110 2021-12-16 Buy
ApexBio Technology B6075 Monastrol 50mg $390 2021-12-16 Buy
Biorbyt Ltd orb546088 Monastrol >98% 5mg $209.1 2021-12-16 Buy
Biorbyt Ltd orb546088 Monastrol >98% 25mg $554.2 2021-12-16 Buy
Biorbyt Ltd orb146117 Monastrol >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb146117 Monastrol >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb146117 Monastrol >98% 1g $2395.3 2021-12-16 Buy
Cayman Chemical 15044 Monastrol ≥98% 1mg $68 2024-03-01 Buy
Cayman Chemical 15044 Monastrol ≥98% 5mg $104 2024-03-01 Buy

Properties

Melting point :190-193℃ (ethanol )
Boiling point :441.3±55.0 °C(Predicted)
Density :1.34±0.1 g/cm3 (20 ºC 760 Torr)
RTECS :UV6262400
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)
form :White to light yellow solid.
pka :9.63±0.10(Predicted)
color :White to Off-White
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Monastrol is a reversible, cell-permeable inhibitor of the motor protein Eg5 (kinesin family protein 11, Kif11), blocking basal ATPase activity in vitro (IC50 = 6.1 μM) and inducing the formation of monoastral spindles in cell-based assays (IC50 = 51.3 μM). It arrests cells in mitosis without targeting tubulin and, as a result, does not interfere with microtubule dependent processes. Monastrol induces activation of the spindle assembly checkpoint and the resulting mitotic arrest can lead to cell death in certain tumor cell lines.