MOZ-IN-3
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- $37 - $2850
- Product name: MOZ-IN-3
- CAS: 2055397-18-5
- MF: C20H17FN2O3S
- MW: 384.42
- EINECS:-0
- MDL Number:
- Synonyms:MOZ-IN-3;[1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-5-methyl-, 2-(phenylsulfonyl)hydrazide;MOZ-IN-3/WM-8014;WM-8014;WM 8014;WM8014;KAT6A INHIBITOR; KAT6B INHIBITOR;KAT6B inhibitor;KAT6A inhibitor;1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-5-methyl-, 3-(phenylsulfonyl)hydrazide;WM-8014,HAT,inhibit,Inhibitor,HATs,WM 8014,Histone Acetyltransferase,WM8014
14 prices
Selected condition:
Brand
- AK Scientific
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4893EL
- Product descriptionCID133053564
- Packaging50mg
- Price$735
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBW166844
- Product descriptionWM 8014 NEW
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBW166844
- Product descriptionWM 8014 NEW
- Packaging50mg
- Price$507.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27402
- Product descriptionMOZ-IN-3
- Packaging500μg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27402
- Product descriptionMOZ-IN-3
- Packaging1mg
- Price$65
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27402
- Product descriptionMOZ-IN-3
- Packaging5mg
- Price$178
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0022886
- Product descriptionWM-8014 99.64%
- Packaging5mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0022886
- Product descriptionWM-8014 99.64%
- Packaging10mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0022886
- Product descriptionWM-8014 99.64%
- Packaging25mg
- Price$1100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0022886
- Product descriptionWM-8014 99.64%
- Packaging50mg
- Price$1850
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0022886
- Product descriptionWM-8014 99.64%
- Packaging100mg
- Price$2850
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10880
- Product descriptionWM-8014 >98%
- Packaging250mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10880
- Product descriptionWM-8014 >98%
- Packaging1g
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM732725
- Product descriptionMOZ-IN-3
- Packaging25mg
- Price$1100
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4893EL | CID133053564 | 50mg | $735 | 2021-12-16 | Buy |
Biosynth Carbosynth | BW166844 | WM 8014 NEW | 10mg | $145 | 2021-12-16 | Buy |
Biosynth Carbosynth | BW166844 | WM 8014 NEW | 50mg | $507.5 | 2021-12-16 | Buy |
Cayman Chemical | 27402 | MOZ-IN-3 | 500μg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 27402 | MOZ-IN-3 | 1mg | $65 | 2024-03-01 | Buy |
Cayman Chemical | 27402 | MOZ-IN-3 | 5mg | $178 | 2024-03-01 | Buy |
ChemScene | CS-0022886 | WM-8014 99.64% | 5mg | $350 | 2021-12-16 | Buy |
ChemScene | CS-0022886 | WM-8014 99.64% | 10mg | $550 | 2021-12-16 | Buy |
ChemScene | CS-0022886 | WM-8014 99.64% | 25mg | $1100 | 2021-12-16 | Buy |
ChemScene | CS-0022886 | WM-8014 99.64% | 50mg | $1850 | 2021-12-16 | Buy |
ChemScene | CS-0022886 | WM-8014 99.64% | 100mg | $2850 | 2021-12-16 | Buy |
DC Chemicals | DC10880 | WM-8014 >98% | 250mg | $980 | 2021-12-16 | Buy |
DC Chemicals | DC10880 | WM-8014 >98% | 1g | $1900 | 2021-12-16 | Buy |
TRC | M732725 | MOZ-IN-3 | 25mg | $1100 | 2021-12-16 | Buy |
Properties
Density :1.307±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMF:PBS (pH 7.2) (1:7): 0.1 mg/ml; DMSO: 33 mg/ml; Ethanol: 2 mg/ml
form :A crystalline solid
pka :7.15±0.25(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMF:PBS (pH 7.2) (1:7): 0.1 mg/ml; DMSO: 33 mg/ml; Ethanol: 2 mg/ml
form :A crystalline solid
pka :7.15±0.25(Predicted)
color :White to off-white
Safety Information
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Description
MOZ-IN-3 is an inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ) and KAT6B/MORF (IC50s = 8 and 28 nM, respectively). It is selective for KAT6A and KAT6B over KAT5 and KAT7 (IC50s = 224 and 342 nM, respectively). MOZ-IN-3 induces cell cycle arrest in and inhibits proliferation of mouse embryonic fibroblasts (IC50 = 2.4 μM) and inhibits proliferation of EMRK1184 lymphoma cells (IC50 = 2.3 μM). It induces genetic and morphological changes associated with cellular senescence without inducing DNA damage, apoptosis, or necrosis. MOZ-IN-3 (10 μM) decreases global levels of acetylated histone H3 lysine 14 (H3K14Ac) by 49% and reduces H3K9Ac levels at the transcription start sites of Ezh2, Melk, and E2f2.Suppliers and manufacturers
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ShangHai Biochempartner Co.,Ltd
Shanghai Rechem science Co., Ltd.