MS37452
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- $38 - $2500
- Product name: MS37452
- CAS: 423748-02-1
- MF: C22H26N2O5
- MW: 398.45224
- EINECS:
- MDL Number:MFCD03134667
- Synonyms:MS37452;1-(2,3-dimethoxybenzoyl)-4-[(3-methylphenoxy)acetyl]piperazine;Ethanone, 1-[4-(2,3-dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-;1-(4-(2,3-Dimethoxybenzoyl)piperazin-1-yl)-2-(m-tolyloxy)ethanone;1-[4-(2,3-Dimethoxybenzoyl)-1-piperazinyl]-2-(3-methylphenoxy)-ethanone;MS 37452,Histone Methyltransferase,transcription,Inhibitor,MS37452,p16/CDKN2A,anticancer,H3K27me3,derepress,CBX7 chromodomain,inhibit,INK4A/ARF,MS-37452
12 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5598
- Product descriptionMS37452
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5598
- Product descriptionMS37452
- Packaging100mg
- Price$990
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5042
- Product descriptionMS37452
- Packaging25mg
- Price$851
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17533
- Product descriptionMS37452 ≥98%
- Packaging1mg
- Price$38
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17533
- Product descriptionMS37452 ≥98%
- Packaging5mg
- Price$111
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17533
- Product descriptionMS37452 ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17533
- Product descriptionMS37452 ≥98%
- Packaging25mg
- Price$412
- Updated2024-03-01
- Buy
- ManufacturerDC Chemicals
- Product numberDC8574
- Product descriptionMS37452 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8574
- Product descriptionMS37452 >98%
- Packaging1g
- Price$2500
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1405
- Product descriptionMS37452 ≥98% (HPLC)
- Packaging5MG
- Price$142
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1405
- Product descriptionMS37452 ≥98% (HPLC)
- Packaging25MG
- Price$451
- Updated2023-06-20
- Buy
- ManufacturerTRC
- Product numberM745825
- Product descriptionMS37452
- Packaging50mg
- Price$865
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5598 | MS37452 | 10mg | $175 | 2021-12-16 | Buy |
| AK Scientific | SYN5598 | MS37452 | 100mg | $990 | 2021-12-16 | Buy |
| ApexBio Technology | C5042 | MS37452 | 25mg | $851 | 2021-12-16 | Buy |
| Cayman Chemical | 17533 | MS37452 ≥98% | 1mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 17533 | MS37452 ≥98% | 5mg | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 17533 | MS37452 ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 17533 | MS37452 ≥98% | 25mg | $412 | 2024-03-01 | Buy |
| DC Chemicals | DC8574 | MS37452 >98% | 100mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC8574 | MS37452 >98% | 1g | $2500 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1405 | MS37452 ≥98% (HPLC) | 5MG | $142 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1405 | MS37452 ≥98% (HPLC) | 25MG | $451 | 2023-06-20 | Buy |
| TRC | M745825 | MS37452 | 50mg | $865 | 2021-12-16 | Buy |
Properties
Boiling point :628.8±55.0 °C(Predicted)
Density :1.209±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
pka :-1.31±0.70(Predicted)
form :powder
color :white to beige
Density :1.209±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
pka :-1.31±0.70(Predicted)
form :powder
color :white to beige
Safety Information
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Description
Chromobox homolog 7 (CBX7) functions through its N-terminal chromodomain, which recognizes histone 3 trimethyl lysine 27 (H3K27me3), to repress gene transcription. It plays a key role in gene transcription in cellular processes related to stem cell self-renewal and differentiation, as well as tumor progression. MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 μM). At 250 μM, it has been shown to derepress transcription of the polycomb repressive complex target gene p16/CDKN2A in prostate cancer cells.Suppliers and manufacturers
TargetMol Chemicals Inc.
Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Changyan Chem & Tech Co., Ltd.
Beijing OKA biological technology co., LTD
DC Chemicals
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Absin Bioscience Inc.
MedBioPharmaceutical Technology Inc