NI-57
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- $32 - $1335
- Product name: NI-57
- CAS: 1883548-89-7
- MF: C19H17N3O4S
- MW: 383.42
- EINECS:604-604-1
- MDL Number:
- Synonyms:BRPF inhibitor NI57;CS-2795;NI57;NI 57;Benzenesulfonamide, 4-cyano-N-(1,2-dihydro-1,3-dimethyl-2-oxo-6-quinolinyl)-2-methoxy-;Inhibitor,inhibit,NI 57,NI-57,NI57,Epigenetic Reader Domain
22 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- BroadPharm
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number3039EC
- Product descriptionCID91827373
- Packaging50mg
- Price$687
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4097
- Product descriptionNI-57
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4097
- Product descriptionNI-57
- Packaging10mg
- Price$227
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4097
- Product descriptionNI-57
- Packaging50mg
- Price$954
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBN166032
- Product descriptionNI 57
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBN166032
- Product descriptionNI 57
- Packaging50mg
- Price$472.5
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25365
- Product descriptionNI57
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-25365
- Product descriptionNI57
- Packaging25mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17662
- Product descriptionNI-57
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17662
- Product descriptionNI-57
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17662
- Product descriptionNI-57
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17662
- Product descriptionNI-57
- Packaging50mg
- Price$836
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0015636
- Product descriptionNI-57 99.89%
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0015636
- Product descriptionNI-57 99.89%
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0015636
- Product descriptionNI-57 99.89%
- Packaging25mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0015636
- Product descriptionNI-57 99.89%
- Packaging50mg
- Price$680
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3039EC | CID91827373 | 50mg | $687 | 2021-12-16 | Buy |
| ApexBio Technology | C4097 | NI-57 | 5mg | $130 | 2021-12-16 | Buy |
| ApexBio Technology | C4097 | NI-57 | 10mg | $227 | 2021-12-16 | Buy |
| ApexBio Technology | C4097 | NI-57 | 50mg | $954 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BN166032 | NI 57 | 10mg | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BN166032 | NI 57 | 50mg | $472.5 | 2021-12-16 | Buy |
| BroadPharm | BP-25365 | NI57 | 10mg | $160 | 2021-12-16 | Buy |
| BroadPharm | BP-25365 | NI57 | 25mg | $360 | 2021-12-16 | Buy |
| Cayman Chemical | 17662 | NI-57 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17662 | NI-57 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 17662 | NI-57 | 10mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 17662 | NI-57 | 50mg | $836 | 2024-03-01 | Buy |
| ChemScene | CS-0015636 | NI-57 99.89% | 5mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-0015636 | NI-57 99.89% | 10mg | $160 | 2021-12-16 | Buy |
| ChemScene | CS-0015636 | NI-57 99.89% | 25mg | $360 | 2021-12-16 | Buy |
| ChemScene | CS-0015636 | NI-57 99.89% | 50mg | $680 | 2021-12-16 | Buy |
Properties
Boiling point :580.1±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤25mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
pka :7.89±0.20(Predicted)
color :White to off-white
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤25mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
pka :7.89±0.20(Predicted)
color :White to off-white
Safety Information
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Description
The bromodomain and PHD finger-containing (BRPF) proteins are scaffolding components of chromatin-binding MOZ/MORF histone acetyltransferase complexes, which have activity as transcriptional regulators. BRPF1 (BR140 or Peregrin) is important for maintaining Hox gene expression and the development of multiple tissues, axial skeleton, and the hematopoietic system. NI-57 is a potent inhibitor of the bromodomains of BRPF proteins that binds to BRPF1B, BRPF2, and BRPF3 with Kd values of 31, 108, and 408 nM, respectively, as determined by isothermal titration calorimetry. It is selective for BRPFs over other bromodomains. NI-57 shows accelerated FRAP recovery at 1 μM in the BRPF2 FRAP assay, preventing binding of full-length BRPF2 to chromatin. See the Structural Genomics Consortium (SGC) website for more information.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
InvivoChem
Jilin Chinese Academy of Sciences-yanshen Technology
Amadis Chemical Company Limited
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai Chaolan Chemical Technology Center
Suzhou Ran enzyme Biotechnology Co., Ltd.