NOMIFENSINE MALEATE
- $44 - $4770
- Product name: NOMIFENSINE MALEATE
- CAS: 24526-64-5
- MF: C16H18N2
- MW: 238.33
- EINECS:
- MDL Number:MFCD00242716
- Synonyms:1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamin ;1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-isoquinolin ;2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinamine;8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline;8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline;8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-;linamiphen ;Nomifenison
12 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- Crysdot
- Matrix Scientific
Package
- 25mg
- 50mg
- 100mg
- 500MG
- 5g
- 10g
- ManufacturerAK Scientific
- Product numberV1991
- Product descriptionNomifensine
- Packaging5g
- Price$1975
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0299991
- Product description2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00%
- Packaging500MG
- Price$679.14
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0299991
- Product description2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00%
- Packaging5G
- Price$1855.51
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29330
- Product descriptionNomifensine
- Packaging25mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29330
- Product descriptionNomifensine
- Packaging50mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29330
- Product descriptionNomifensine
- Packaging100mg
- Price$138
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-4708
- Product descriptionNomifensine 98.93%
- Packaging50mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-4708
- Product descriptionNomifensine 98.93%
- Packaging100mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002531
- Product descriptionNomifensine 98+%
- Packaging50mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002531
- Product descriptionNomifensine 98+%
- Packaging100mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number131948
- Product description2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97%
- Packaging5g
- Price$2970
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number131948
- Product description2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97%
- Packaging10g
- Price$4770
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | V1991 | Nomifensine | 5g | $1975 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0299991 | 2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00% | 500MG | $679.14 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0299991 | 2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00% | 5G | $1855.51 | 2021-12-16 | Buy |
Cayman Chemical | 29330 | Nomifensine | 25mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 29330 | Nomifensine | 50mg | $78 | 2024-03-01 | Buy |
Cayman Chemical | 29330 | Nomifensine | 100mg | $138 | 2024-03-01 | Buy |
ChemScene | CS-4708 | Nomifensine 98.93% | 50mg | $108 | 2021-12-16 | Buy |
ChemScene | CS-4708 | Nomifensine 98.93% | 100mg | $192 | 2021-12-16 | Buy |
Crysdot | CD31002531 | Nomifensine 98+% | 50mg | $62 | 2021-12-16 | Buy |
Crysdot | CD31002531 | Nomifensine 98+% | 100mg | $111 | 2021-12-16 | Buy |
Matrix Scientific | 131948 | 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97% | 5g | $2970 | 2021-12-16 | Buy |
Matrix Scientific | 131948 | 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97% | 10g | $4770 | 2021-12-16 | Buy |
Properties
Melting point :179-181°
Boiling point :370.93°C (rough estimate)
Density :0.9597 (rough estimate)
refractive index :1.5000 (estimate)
storage temp. :2-8°C(protect from light)
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): Partially soluble
form :A crystalline solid
pka :7.85±0.40(Predicted)
color :Light yellow to yellow
EPA Substance Registry System :Nomifensine (24526-64-5)
Boiling point :370.93°C (rough estimate)
Density :0.9597 (rough estimate)
refractive index :1.5000 (estimate)
storage temp. :2-8°C(protect from light)
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): Partially soluble
form :A crystalline solid
pka :7.85±0.40(Predicted)
color :Light yellow to yellow
EPA Substance Registry System :Nomifensine (24526-64-5)
Safety Information
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Nomifensine is an inhibitor of norepinephrine (NE) and dopamine (DA) reuptake. It inhibits uptake of NE, DA, and serotonin (5-HT) in rat brain synaptosomes with IC50 values of 6.6, 48, and 830 nM, respectively. It is selective for DA, NE, and 5-HT uptake inhibition over binding to dopamine D2, α1- adrenergic-, 5-HT2, and muscarinic receptors (IC50s = 43,000, 1,200, 3,800, and >13,000 nM, respectively, in rat brain membranes). Nomifensine is selective for inhibition of NE over DA uptake in vivo with minimal inhibitory doses of 28 and less than 57 μmol/kg, respectively. It decreases the time Wistar Kyoto, but not Sprague-Dawley, rats spend immobile in the forced swim test but also increases locomotor activity in the open field test in Wistar Kyoto and Sprague-Dawley rats when administered at a chronic dose of 10 mg/kg.Related product price
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