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ChemicalBook >> CAS DataBase List >> NOMIFENSINE MALEATE

NOMIFENSINE MALEATE

NOMIFENSINE MALEATE price.
  • $44 - $4770
  • Product name: NOMIFENSINE MALEATE
  • CAS: 24526-64-5
  • MF: C16H18N2
  • MW: 238.33
  • EINECS:
  • MDL Number:MFCD00242716
  • Synonyms:1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamin ;1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-isoquinolin ;2-Methyl-4-phenyl-1,2,3,4-tetrahydro-8-isoquinolinamine;8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline;8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline;8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-;linamiphen ;Nomifenison
12 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Matrix Scientific
Package
  • 25mg
  • 50mg
  • 100mg
  • 500MG
  • 5g
  • 10g
  • ManufacturerAK Scientific
  • Product numberV1991
  • Product descriptionNomifensine
  • Packaging5g
  • Price$1975
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0299991
  • Product description2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00%
  • Packaging500MG
  • Price$679.14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0299991
  • Product description2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00%
  • Packaging5G
  • Price$1855.51
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29330
  • Product descriptionNomifensine
  • Packaging25mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29330
  • Product descriptionNomifensine
  • Packaging50mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29330
  • Product descriptionNomifensine
  • Packaging100mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4708
  • Product descriptionNomifensine 98.93%
  • Packaging50mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4708
  • Product descriptionNomifensine 98.93%
  • Packaging100mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002531
  • Product descriptionNomifensine 98+%
  • Packaging50mg
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002531
  • Product descriptionNomifensine 98+%
  • Packaging100mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number131948
  • Product description2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97%
  • Packaging5g
  • Price$2970
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number131948
  • Product description2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97%
  • Packaging10g
  • Price$4770
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific V1991 Nomifensine 5g $1975 2021-12-16 Buy
American Custom Chemicals Corporation CHM0299991 2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00% 500MG $679.14 2021-12-16 Buy
American Custom Chemicals Corporation CHM0299991 2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-YLAMINE 95.00% 5G $1855.51 2021-12-16 Buy
Cayman Chemical 29330 Nomifensine 25mg $44 2024-03-01 Buy
Cayman Chemical 29330 Nomifensine 50mg $78 2024-03-01 Buy
Cayman Chemical 29330 Nomifensine 100mg $138 2024-03-01 Buy
ChemScene CS-4708 Nomifensine 98.93% 50mg $108 2021-12-16 Buy
ChemScene CS-4708 Nomifensine 98.93% 100mg $192 2021-12-16 Buy
Crysdot CD31002531 Nomifensine 98+% 50mg $62 2021-12-16 Buy
Crysdot CD31002531 Nomifensine 98+% 100mg $111 2021-12-16 Buy
Matrix Scientific 131948 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97% 5g $2970 2021-12-16 Buy
Matrix Scientific 131948 2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine 97% 10g $4770 2021-12-16 Buy

Properties

Melting point :179-181°
Boiling point :370.93°C (rough estimate)
Density :0.9597 (rough estimate)
refractive index :1.5000 (estimate)
storage temp. :2-8°C(protect from light)
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): Partially soluble
form :A crystalline solid
pka :7.85±0.40(Predicted)
color :Light yellow to yellow
EPA Substance Registry System :Nomifensine (24526-64-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Nomifensine is an inhibitor of norepinephrine (NE) and dopamine (DA) reuptake. It inhibits uptake of NE, DA, and serotonin (5-HT) in rat brain synaptosomes with IC50 values of 6.6, 48, and 830 nM, respectively. It is selective for DA, NE, and 5-HT uptake inhibition over binding to dopamine D2, α1- adrenergic-, 5-HT2, and muscarinic receptors (IC50s = 43,000, 1,200, 3,800, and >13,000 nM, respectively, in rat brain membranes). Nomifensine is selective for inhibition of NE over DA uptake in vivo with minimal inhibitory doses of 28 and less than 57 μmol/kg, respectively. It decreases the time Wistar Kyoto, but not Sprague-Dawley, rats spend immobile in the forced swim test but also increases locomotor activity in the open field test in Wistar Kyoto and Sprague-Dawley rats when administered at a chronic dose of 10 mg/kg.

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