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ChemicalBook >> CAS DataBase List >> NS 1619

NS 1619

NS 1619 price.
  • $10 - $3176
  • Product name: NS 1619
  • CAS: 153587-01-0
  • MF: C15H8F6N2O2
  • MW: 362.23
  • EINECS:
  • MDL Number:MFCD00928190
  • Synonyms:NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;NS1619;NS 1619;NS 161;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-
20 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 0.05g
  • 100mg
  • 250mg
  • ManufacturerAHH
  • Product numberMT-20299
  • Product descriptionNS 1619 98%
  • Packaging0.05g
  • Price$368
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX6428
  • Product description1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one
  • Packaging5mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA900983
  • Product descriptionNS 1619 98+%
  • Packaging1mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA900983
  • Product descriptionNS 1619 98+%
  • Packaging10mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA900983
  • Product descriptionNS 1619 98+%
  • Packaging250mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7502
  • Product descriptionNS 1619
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18876
  • Product descriptionNS 1619 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18876
  • Product descriptionNS 1619 ≥98%
  • Packaging5mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18876
  • Product descriptionNS 1619 ≥98%
  • Packaging10mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18876
  • Product descriptionNS 1619 ≥98%
  • Packaging25mg
  • Price$222
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3613
  • Product descriptionNS 1619 >98.0%
  • Packaging5mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3613
  • Product descriptionNS 1619 >98.0%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003277
  • Product descriptionNS 1619 98+%
  • Packaging10mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9734
  • Product descriptionNS 1619 >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number097002
  • Product description1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one 95+%
  • Packaging250mg
  • Price$3176
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberN170
  • Product descriptionNS 1619 powder
  • Packaging5mg
  • Price$180
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-20299 NS 1619 98% 0.05g $368 2021-12-16 Buy
AK Scientific X6428 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one 5mg $136 2021-12-16 Buy
Ambeed A900983 NS 1619 98+% 1mg $10 2021-12-16 Buy
Ambeed A900983 NS 1619 98+% 10mg $33 2021-12-16 Buy
Ambeed A900983 NS 1619 98+% 250mg $238 2021-12-16 Buy
ApexBio Technology B7502 NS 1619 10mg $108 2021-12-16 Buy
Cayman Chemical 18876 NS 1619 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 18876 NS 1619 ≥98% 5mg $81 2024-03-01 Buy
Cayman Chemical 18876 NS 1619 ≥98% 10mg $142 2024-03-01 Buy
Cayman Chemical 18876 NS 1619 ≥98% 25mg $222 2024-03-01 Buy
ChemScene CS-3613 NS 1619 >98.0% 5mg $82 2021-12-16 Buy
ChemScene CS-3613 NS 1619 >98.0% 10mg $120 2021-12-16 Buy
Crysdot CD31003277 NS 1619 98+% 10mg $124 2021-12-16 Buy
DC Chemicals DC9734 NS 1619 >98% 100mg $550 2021-12-16 Buy
Matrix Scientific 097002 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one 95+% 250mg $3176 2021-12-16 Buy
Sigma-Aldrich N170 NS 1619 powder 5mg $180 2024-03-01 Buy

Properties

Density :1.563±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka :8.32±0.48(Predicted)
form :solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NS 1619 is a calcium-dependent activator of large-conductance Ca2+-activated K+ (BKCa) channels in vascular smooth muscle. It is typically used at a concentration of 30 μM to hyperpolarize the membrane potential of single myocytes during studies of smooth muscle relaxation and vasodilation. Studies suggest that activation of BKCa channels by NS 1619 can protect the cardiac muscle against pulmonary hypertension as well as ischemia and reperfusion injury in various animal models.

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