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ChemicalBook >> CAS DataBase List >> NS309

NS309

$48 - $865
Product name: NS309
CAS: 18711-16-5
MF: C8H4Cl2N2O2
MW: 231.04
EINECS:
MDL Number:MFCD06798346
Synonyms:1H-Indole-2,3-dione,6,7-dichloro-, 3-oxiMe;6,7-Dichloroindole-2,3-dione 3-oxime;6,7-Dichloroisatin 3-oxime;6,7-Dichloro-3-(hydroxyiMino)indolin-2-one;NS309;NS 309;NS-309;6,7-Dichloro-1H-indole-2,3-dione3-oxime;NS 309; NS-309;(Z)-6,7-dichloro-3-(hydroxyimino)indolin-2-one

Price16 Properties Safety Information Description

16 prices

Selected condition：

Brand

ApexBio Technology
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
TRC

Package

5mg
10mg
25mg
50mg
100mg
250mg

ManufacturerApexBio Technology
Product numberA3668
Product descriptionNS309
Packaging5mg
Price$81
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3668
Product descriptionNS309
Packaging10mg
Price$107
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3668
Product descriptionNS309
Packaging50mg
Price$374
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number18889
Product descriptionNS309
Packaging5mg
Price$49
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number18889
Product descriptionNS309 ≥98%
Packaging10mg
Price$68
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number18889
Product descriptionNS309 ≥98%
Packaging50mg
Price$286
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-0849
Product descriptionNS309 99.76%
Packaging5mg
Price$60
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0849
Product descriptionNS309 99.76%
Packaging10mg
Price$72
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0849
Product descriptionNS309 99.76%
Packaging50mg
Price$252
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31002864
Product descriptionNS309 98+%
Packaging10mg
Price$48
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31002864
Product descriptionNS309 98+%
Packaging50mg
Price$166
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC7833
Product descriptionNS309 >98%
Packaging100mg
Price$400
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC7833
Product descriptionNS309 >98%
Packaging250mg
Price$750
Updated2021-12-16
Buy

ManufacturerSigma-Aldrich
Product numberN8161
Product descriptionNS309 ≥98% (HPLC), solid
Packaging5mg
Price$161
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product numberN8161
Product descriptionNS309 ≥98% (HPLC), solid
Packaging25mg
Price$635
Updated2024-03-01
Buy

ManufacturerTRC
Product numberN900215
Product descriptionNS309
Packaging250mg
Price$865
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
ApexBio Technology	A3668	NS309	5mg	$81	2021-12-16	Buy
ApexBio Technology	A3668	NS309	10mg	$107	2021-12-16	Buy
ApexBio Technology	A3668	NS309	50mg	$374	2021-12-16	Buy
Cayman Chemical	18889	NS309	5mg	$49	2024-03-01	Buy
Cayman Chemical	18889	NS309 ≥98%	10mg	$68	2024-03-01	Buy
Cayman Chemical	18889	NS309 ≥98%	50mg	$286	2024-03-01	Buy
ChemScene	CS-0849	NS309 99.76%	5mg	$60	2021-12-16	Buy
ChemScene	CS-0849	NS309 99.76%	10mg	$72	2021-12-16	Buy
ChemScene	CS-0849	NS309 99.76%	50mg	$252	2021-12-16	Buy
Crysdot	CD31002864	NS309 98+%	10mg	$48	2021-12-16	Buy
Crysdot	CD31002864	NS309 98+%	50mg	$166	2021-12-16	Buy
DC Chemicals	DC7833	NS309 >98%	100mg	$400	2021-12-16	Buy
DC Chemicals	DC7833	NS309 >98%	250mg	$750	2021-12-16	Buy
Sigma-Aldrich	N8161	NS309 ≥98% (HPLC), solid	5mg	$161	2024-03-01	Buy
Sigma-Aldrich	N8161	NS309 ≥98% (HPLC), solid	25mg	$635	2024-03-01	Buy
TRC	N900215	NS309	250mg	$865	2021-12-16	Buy

Properties

Melting point :190-192℃
storage temp. :2-8°C
solubility :DMSO: ~22 mg/mL
form :solid
color :yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 μM for SK channels and 10-90 nM for IK channels). It can also activate voltage-gated Kv11.1 channels (hERG; IC50 = 1 μM), but does not, however, affect large conductance (BK/KCa1.1) channels. NS309 can modulate neuronal firing patterns by enhancing SK-mediated hyperpolarizing effects. It is 730-fold (SK channels) and 7,400-fold (IK channels) more potent than 1-EBIO and often used in conjunction with CyPPA to distinguish between SK1 and SK3 subtypes.

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