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ChemicalBook >> CAS DataBase List >> NSC764414

NSC764414

NSC764414 price.
  • $63 - $900
  • Product name: NSC764414
  • CAS: 321695-57-2
  • MF: C15H15NO5S
  • MW: 321.35
  • EINECS:
  • MDL Number:
  • Synonyms:4-[O-[(4-Methoxyphenyl)sulfonyl]oxime]-2,6-dimethyl-2,5-cyclohexadiene-1,4-dione;L002;NSC764414;p300/CBP Inhibitor VI, L002 ;[(3,5-dimethyl-4-oxo-cyclohexa-2,5-dien-1-ylidene)amino] 4-methoxybenzenesulfonate;L002(NSC764414);L 002;NSC 764414;L-002;NSC-764414;p300/CBP Inhibitor VI, L002 - CAS 321695-57-2 - Calbiochem
22 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product numberSYN5191
  • Product descriptionL002
  • Packaging50mg
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7739
  • Product descriptionL002
  • Packaging25mg
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7739
  • Product descriptionL002
  • Packaging50mg
  • Price$587
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2319
  • Product descriptionL002-NSC764414 99%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17778
  • Product descriptionL002 ≥98%
  • Packaging5mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17778
  • Product descriptionL002 ≥98%
  • Packaging10mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17778
  • Product descriptionL002 ≥98%
  • Packaging25mg
  • Price$278
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17778
  • Product descriptionL002 ≥98%
  • Packaging50mg
  • Price$515
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019911
  • Product descriptionL002 98.80%
  • Packaging5mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019911
  • Product descriptionL002 98.80%
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019911
  • Product descriptionL002 98.80%
  • Packaging25mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019911
  • Product descriptionL002 98.80%
  • Packaging50mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019911
  • Product descriptionL002 98.80%
  • Packaging100mg
  • Price$695
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8578
  • Product descriptionL002(NSC764414) >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8578
  • Product descriptionL002(NSC764414) >98%
  • Packaging250mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0759
  • Product descriptionL002 ≥98% (HPLC)
  • Packaging5mg
  • Price$105
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5191 L002 50mg $410 2021-12-16 Buy
ApexBio Technology B7739 L002 25mg $316 2021-12-16 Buy
ApexBio Technology B7739 L002 50mg $587 2021-12-16 Buy
Axon Medchem Axon2319 L002-NSC764414 99% 10mg $88 2021-12-16 Buy
Cayman Chemical 17778 L002 ≥98% 5mg $81 2024-03-01 Buy
Cayman Chemical 17778 L002 ≥98% 10mg $120 2024-03-01 Buy
Cayman Chemical 17778 L002 ≥98% 25mg $278 2024-03-01 Buy
Cayman Chemical 17778 L002 ≥98% 50mg $515 2024-03-01 Buy
ChemScene CS-0019911 L002 98.80% 5mg $63 2021-12-16 Buy
ChemScene CS-0019911 L002 98.80% 10mg $95 2021-12-16 Buy
ChemScene CS-0019911 L002 98.80% 25mg $220 2021-12-16 Buy
ChemScene CS-0019911 L002 98.80% 50mg $420 2021-12-16 Buy
ChemScene CS-0019911 L002 98.80% 100mg $695 2021-12-16 Buy
DC Chemicals DC8578 L002(NSC764414) >98% 100mg $500 2021-12-16 Buy
DC Chemicals DC8578 L002(NSC764414) >98% 250mg $900 2021-12-16 Buy
Sigma-Aldrich SML0759 L002 ≥98% (HPLC) 5mg $105 2024-03-01 Buy

Properties

Boiling point :459.8±55.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

L002 is an inhibitor of p300 histone acetyltransferase (KAT3B; IC50 = 1.98 μM in vitro). It has weaker inhibitory effects against PCAF and GCN5 (IC50s = 35 and 34 μM, respectively) and is specific for p300 over a panel of additional acetyltransferases, deacetylases, and methyltransferases. L002 blocks acetylation of histones and p53 in cells treated with trichostatin A or etoposide, respectively, and reduces STAT3 phosphorylation, which requires p300-mediated acetylation of STAT3. It induces growth arrest and apoptosis in certain cancer cell lines and, when administered intraperitoneally in mice, suppresses the growth of triple-negative breast cancer xenografts.