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ChemicalBook >> CAS DataBase List >> Naloxegol Oxalate

Naloxegol Oxalate

Naloxegol Oxalate price.
  • $50 - $1459
  • Product name: Naloxegol Oxalate
  • CAS: 1354744-91-4
  • MF: C36H55NO15
  • MW: 741.83
  • EINECS:1592732-453-0
  • MDL Number:MFCD29472292
  • Synonyms:Naloxegol Oxalate;Naloxegol Oxalate NKTR-118;(5alpha,6alpha)-4,5-Epoxy-6-(3,6,9,12,15,18,21-heptaoxadocos-1-yloxy)-17-(2-propen-1-yl)-morphinan-3,14-diol ethanedioate;AZ 13337019 oxalate;NKTR 118 oxalate;(4R,4aS,7S,7aR,12bS)-7-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol,oxalic acid;Naloxegol oxalate salt;Naloxegol OxalateQ: What is Naloxegol Oxalate Q: What is the CAS Number of Naloxegol Oxalate Q: What is the storage condition of Naloxegol Oxalate
Price16 Properties Safety Information Description
16 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number2121DN
  • Product descriptionNaloxegoloxalate
  • Packaging25mg
  • Price$735
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23731
  • Product descriptionNaloxegol (oxalate) ≥98%
  • Packaging5mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23731
  • Product descriptionNaloxegol (oxalate) ≥98%
  • Packaging10mg
  • Price$319
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23731
  • Product descriptionNaloxegol (oxalate) ≥98%
  • Packaging25mg
  • Price$573
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23731
  • Product descriptionNaloxegol (oxalate) ≥98%
  • Packaging50mg
  • Price$935
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5349
  • Product descriptionNaloxegol(oxalate) 99.90%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5349
  • Product descriptionNaloxegol(oxalate) 99.90%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5349
  • Product descriptionNaloxegol(oxalate) 99.90%
  • Packaging50mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5349
  • Product descriptionNaloxegol(oxalate) 99.90%
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003765
  • Product descriptionNaloxegoloxalate 98+%
  • Packaging5mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003765
  • Product descriptionNaloxegoloxalate 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003765
  • Product descriptionNaloxegoloxalate 98+%
  • Packaging50mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003765
  • Product descriptionNaloxegoloxalate 98+%
  • Packaging100mg
  • Price$1459
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8492
  • Product descriptionNaloxegolOxalate(NKTR-118) >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8492
  • Product descriptionNaloxegolOxalate(NKTR-118) >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN284475
  • Product descriptionNaloxegolOxalate
  • Packaging25mg
  • Price$475
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2121DN Naloxegoloxalate 25mg $735 2021-12-16 Buy
Cayman Chemical 23731 Naloxegol (oxalate) ≥98% 5mg $178 2024-03-01 Buy
Cayman Chemical 23731 Naloxegol (oxalate) ≥98% 10mg $319 2024-03-01 Buy
Cayman Chemical 23731 Naloxegol (oxalate) ≥98% 25mg $573 2024-03-01 Buy
Cayman Chemical 23731 Naloxegol (oxalate) ≥98% 50mg $935 2024-03-01 Buy
ChemScene CS-5349 Naloxegol(oxalate) 99.90% 5mg $50 2021-12-16 Buy
ChemScene CS-5349 Naloxegol(oxalate) 99.90% 10mg $70 2021-12-16 Buy
ChemScene CS-5349 Naloxegol(oxalate) 99.90% 50mg $180 2021-12-16 Buy
ChemScene CS-5349 Naloxegol(oxalate) 99.90% 100mg $250 2021-12-16 Buy
Crysdot CD31003765 Naloxegoloxalate 98+% 5mg $243 2021-12-16 Buy
Crysdot CD31003765 Naloxegoloxalate 98+% 10mg $347 2021-12-16 Buy
Crysdot CD31003765 Naloxegoloxalate 98+% 50mg $1042 2021-12-16 Buy
Crysdot CD31003765 Naloxegoloxalate 98+% 100mg $1459 2021-12-16 Buy
DC Chemicals DC8492 NaloxegolOxalate(NKTR-118) >98% 100mg $550 2021-12-16 Buy
DC Chemicals DC8492 NaloxegolOxalate(NKTR-118) >98% 250mg $1100 2021-12-16 Buy
TRC N284475 NaloxegolOxalate 25mg $475 2021-12-16 Buy

Properties

Melting point :92-95°C
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Naloxegol oxalate (XXI) is a peripherally acting μ-opioid receptor antagonist that was approved in the USA and EU for the treatment of opioid-induced constipation in adults with chronic non-cancer pain. The drug, a pegylated version of naloxone, has significantly reduced central nervous system (CNS) penetration and works by inhibiting the binding of opioids in the gastrointestinal tract. Naloxegol oxalate was developed by Nektar and licensed to AstraZeneca. Although we were unable to find a single report in the primary or patent literature that describes the exact experimental procedures to prepare naloxegol oxalate, there have been reports on the preparation of closely related analogs with specific reports on improving the selectivity of the reduction step156 and the salt formation of the final drug substance.

Suppliers and manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Naloxegol Oxalate
$0.00 /25KG
Naloxegol Oxalate CAS:1354744-91-4
Hebei Weibang Biotechnology Co., Ltd
Naloxegol Oxalate
$1.00 /10kg
Naloxegol Oxalate CAS:1354744-91-4
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Naloxegol Oxalate
$0.00 /1g
Naloxegol Oxalate CAS:1354744-91-4
TargetMol Chemicals Inc.
Naloxegol oxalate
$40.00 /5mg
Naloxegol oxalate CAS:1354744-91-4
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Hebei Yanxi Chemical Co., Ltd.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
InvivoChem