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ChemicalBook >> CAS DataBase List >> Nampt-IN-1

Nampt-IN-1

Nampt-IN-1 price.
  • $44 - $2520
  • Product name: Nampt-IN-1
  • CAS: 1698878-14-6
  • MF: C20H25N3O5S
  • MW: 419.49
  • EINECS:
  • MDL Number:MFCD28963946
  • Synonyms:Nampt-IN-1;2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide;2-Hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-isoquinolinyl]-1-propanesulfonamide;LSN3154567 (Nampt-IN-1);LSN3154567;2-hydroxy-2-methyl-N-[1,2,3,4-tetrahydro-2-[2-(3-pyridinyloxy)acetyl]-6-;LSN 3154567;LSN-3154567;LSN3154567;Nampt inhibitor 1
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • AK Scientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number4484EC
  • Product descriptionNampt-IN-1
  • Packaging10mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL165041
  • Product descriptionLSN 3154567 NEW
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBL165041
  • Product descriptionLSN 3154567 NEW
  • Packaging50mg
  • Price$437.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26066
  • Product descriptionNampt-IN-1 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26066
  • Product descriptionNampt-IN-1 ≥98%
  • Packaging5mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26066
  • Product descriptionNampt-IN-1 ≥98%
  • Packaging10mg
  • Price$321
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26066
  • Product descriptionNampt-IN-1 ≥98%
  • Packaging25mg
  • Price$699
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM146135
  • Product description2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide 98%
  • Packaging100mg
  • Price$1374
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5008
  • Product descriptionNampt-IN-1 99.48%
  • Packaging5mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5008
  • Product descriptionNampt-IN-1 99.48%
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5008
  • Product descriptionNampt-IN-1 99.48%
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5008
  • Product descriptionNampt-IN-1 99.48%
  • Packaging100mg
  • Price$2520
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10665
  • Product descriptionLSN3154567(Nampt-IN-1) >98%
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2249
  • Product descriptionLSN3154567 ≥98% (HPLC)
  • Packaging25mg
  • Price$430
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML2249
  • Product descriptionLSN3154567 ≥98% (HPLC)
  • Packaging5mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberN285780
  • Product descriptionNampt-IN-1
  • Packaging50mg
  • Price$1320
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4484EC Nampt-IN-1 10mg $218 2021-12-16 Buy
Biosynth Carbosynth BL165041 LSN 3154567 NEW 10mg $125 2021-12-16 Buy
Biosynth Carbosynth BL165041 LSN 3154567 NEW 50mg $437.5 2021-12-16 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 5mg $172 2024-03-01 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 10mg $321 2024-03-01 Buy
Cayman Chemical 26066 Nampt-IN-1 ≥98% 25mg $699 2024-03-01 Buy
Chemenu CM146135 2-hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide 98% 100mg $1374 2021-12-16 Buy
ChemScene CS-5008 Nampt-IN-1 99.48% 5mg $420 2021-12-16 Buy
ChemScene CS-5008 Nampt-IN-1 99.48% 10mg $600 2021-12-16 Buy
ChemScene CS-5008 Nampt-IN-1 99.48% 50mg $1800 2021-12-16 Buy
ChemScene CS-5008 Nampt-IN-1 99.48% 100mg $2520 2021-12-16 Buy
DC Chemicals DC10665 LSN3154567(Nampt-IN-1) >98% 100mg $700 2021-12-16 Buy
Sigma-Aldrich SML2249 LSN3154567 ≥98% (HPLC) 25mg $430 2024-03-01 Buy
Sigma-Aldrich SML2249 LSN3154567 ≥98% (HPLC) 5mg $107 2024-03-01 Buy
TRC N285780 Nampt-IN-1 50mg $1320 2021-12-16 Buy
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Properties

Boiling point :659.9±65.0 °C(Predicted)
Density :1.363±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: Soluble
form :powder
pka :8.67±0.20(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Nampt-IN-1 is a potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt; IC50 = 3.1 nM). It is selective for Nampt over a panel of greater than 100 human kinases at 1 μM. Nampt-IN-1 inhibits NAD+ formation in and proliferation of HCT116 cells (IC50s = 1.8 and 8.9 nM, respectively). It inhibits cell growth in a panel of cancer cell lines (IC50s = <0.2-2 μM). Nampt-IN-1 inhibits NAD+ formation in an A2780 ovarian carcinoma mouse xenograft model (ED50 = 2 mg/kg).

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