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ChemicalBook >> CAS DataBase List >> Necrosis Inhibitor, IM-54

Necrosis Inhibitor, IM-54

Necrosis Inhibitor, IM-54 price.
  • $31 - $968
  • Product name: Necrosis Inhibitor, IM-54
  • CAS: 861891-50-1
  • MF: C19H23N3O2
  • MW: 325.4
  • EINECS:804-593-4
  • MDL Number:MFCD18382109
  • Synonyms:Necrosis Inhibitor, IM-54;IM-54;1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione;2-(1H-Indol-3-yl)-3-pentylamino-maleimide;1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione;IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide);Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem;1H-Pyrrole-2,5-dione, 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-
11 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product numberSYN5549
  • Product descriptionIM-54
  • Packaging50mg
  • Price$968
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64372
  • Product descriptionNecrosis Inhibitor, IM-54
  • Packaging5mg
  • Price$283
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0125684
  • Product description1-METHYL-3-(1-METHYL-1H-INDOL-3-YL)-4-(PENTYLAMINO)-1H-PYRROLE-2,5-DIONE 95.00%
  • Packaging5MG
  • Price$505.11
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13323
  • Product descriptionIM-54 ≥95%
  • Packaging1mg
  • Price$31
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13323
  • Product descriptionIM-54 ≥95%
  • Packaging5mg
  • Price$133
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13323
  • Product descriptionIM-54 ≥95%
  • Packaging10mg
  • Price$234
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13323
  • Product descriptionIM-54 ≥95%
  • Packaging25mg
  • Price$510
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0412
  • Product descriptionIM-54 ≥98% (HPLC)
  • Packaging5mg
  • Price$197
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number480060
  • Product descriptionNecrosis Inhibitor, IM-54
  • Packaging5mg
  • Price$259
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0412
  • Product descriptionIM-54 ≥98% (HPLC)
  • Packaging25mg
  • Price$696
  • Updated2022-05-15
  • Buy
  • ManufacturerTRC
  • Product numberN388603
  • Product descriptionNecrosis Inhibitor, IM-54
  • Packaging5mg
  • Price$115
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5549 IM-54 50mg $968 2021-12-16 Buy
Alfa Aesar J64372 Necrosis Inhibitor, IM-54 5mg $283 2023-06-20 Buy
American Custom Chemicals Corporation CHM0125684 1-METHYL-3-(1-METHYL-1H-INDOL-3-YL)-4-(PENTYLAMINO)-1H-PYRROLE-2,5-DIONE 95.00% 5MG $505.11 2021-12-16 Buy
Cayman Chemical 13323 IM-54 ≥95% 1mg $31 2024-03-01 Buy
Cayman Chemical 13323 IM-54 ≥95% 5mg $133 2024-03-01 Buy
Cayman Chemical 13323 IM-54 ≥95% 10mg $234 2024-03-01 Buy
Cayman Chemical 13323 IM-54 ≥95% 25mg $510 2024-03-01 Buy
Sigma-Aldrich SML0412 IM-54 ≥98% (HPLC) 5mg $197 2024-03-01 Buy
Sigma-Aldrich 480060 Necrosis Inhibitor, IM-54 5mg $259 2024-03-01 Buy
Sigma-Aldrich SML0412 IM-54 ≥98% (HPLC) 25mg $696 2022-05-15 Buy
TRC N388603 Necrosis Inhibitor, IM-54 5mg $115 2021-12-16 Buy

Properties

Boiling point :511.5±50.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL (clear solution)
form :Yellow orange solid
pka :1.96±0.20(Predicted)
color :light orange to dark orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P321 Specific treatment (see … on this label).
P405 Store locked up.

Description

IM-54 is an indolylmaleimide derivative which, at 1 μM, inhibits necrotic cell death induced by H2O2 in promyelocytic leukemia HL-60 cells. It does not prevent etoposide-induced apoptosis and does not inhibit protein kinase C or S6 kinase 1.