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ChemicalBook >> CAS DataBase List >> Nocloprost

Nocloprost

Nocloprost price.
  • $61 - $1470
  • Product name: Nocloprost
  • CAS: 79360-43-3
  • MF: C22H37ClO4
  • MW: 400.983
  • EINECS:
  • MDL Number:MFCD00867418
  • Synonyms:Nocloprost;(5Z,13E,15R)-9β-Chloro-11α,15-dihydroxy-16,16-dimethylprosta-5,13-dien-1-oic acid;SH-475;Prosta-5,13-dien-1-oic acid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9β,11α,13E,15R)-;Prosta-5,13-dien-1-oicacid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9b,11a,13E,15R)-
7 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number4510CQ
  • Product descriptionNocloprost
  • Packaging1mg
  • Price$351
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10988
  • Product descriptionNocloprost ≥98%
  • Packaging500μg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10988
  • Product descriptionNocloprost ≥98%
  • Packaging1mg
  • Price$241
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10988
  • Product descriptionNocloprost ≥98%
  • Packaging5mg
  • Price$933
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberN634150
  • Product descriptionNocloprost
  • Packaging1mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN634150
  • Product descriptionNocloprost
  • Packaging5mg
  • Price$775
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberN634150
  • Product descriptionNocloprost
  • Packaging10mg
  • Price$1470
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4510CQ Nocloprost 1mg $351 2021-12-16 Buy
Cayman Chemical 10988 Nocloprost ≥98% 500μg $166 2024-03-01 Buy
Cayman Chemical 10988 Nocloprost ≥98% 1mg $241 2024-03-01 Buy
Cayman Chemical 10988 Nocloprost ≥98% 5mg $933 2023-06-20 Buy
TRC N634150 Nocloprost 1mg $185 2021-12-16 Buy
TRC N634150 Nocloprost 5mg $775 2021-12-16 Buy
TRC N634150 Nocloprost 10mg $1470 2021-12-16 Buy

Properties

Boiling point :539.8±50.0 °C(Predicted)
Density :1.10±0.1 g/cm3(Predicted)
solubility :DMF: 11 mg/ml; DMSO: 10 mg/ml; Ethanol: 16 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
pka :4.76±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Nocloprost is a stable prostaglandin E2 analog with gastroprotective and ulcer-healing properties. As a weak acid (pKa = 5), it accumulates in the gastric mucosa at low pH and can prevent the formation of gastric lesions in rats when administered intragastrically 30 minutes before 100% ethanol, acidified aspirin, acidified taurocholate, water immersion, or restraint stress (ID50s = 0.25, 0.58, 0.06 and 0.12 μg/kg, respectively). Additionally, nocloprost has been used to inhibit evoked acetylcholine release from isolated human bronchi (IC50 = 4 nM) to study factors that regulate human airway smooth muscle tone and secretion.

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