O-689
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- $25 - $807
- Product name: O-689
- CAS: 166100-39-6
- MF: C23H38FNO
- MW: 363.55
- EINECS:200-578-6
- MDL Number:MFCD01862615
- Synonyms:(+/-)-N-(2-FLUOROETHYL)-2-METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;O-689;(+/-)-2-METHYLARACHIDONOYL-2'-FLUOROETHYLAMIDE;(+/-)-2-METHYLARACHIDONYL-2'-FLUOROETHYLAMIDE;2-METHYL-2'-FLUORO AEA;F-2-ME-AN;FLUOROMETHANANDAMIDE;(+/-)-2-METHYLARACHIDONOLY-2'*-FLUOROETHYLAMIDE
6 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number8733CN
- Product description2-Methylarachidonoyl-(2'-fluoroethyl)amide
- Packaging1mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number90055
- Product description(±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95%
- Packaging1mg
- Price$25
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number90055
- Product description(±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95%
- Packaging5mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number90055
- Product description(±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95%
- Packaging10mg
- Price$186
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number90055
- Product description(±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95%
- Packaging50mg
- Price$807
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberM1438
- Product description(±)-2-Methylarachidonoyl-2′-fluoroethylamide ≥95%, ethanol solution
- Packaging5mg
- Price$243
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8733CN | 2-Methylarachidonoyl-(2'-fluoroethyl)amide | 1mg | $125 | 2021-12-16 | Buy |
| Cayman Chemical | 90055 | (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% | 1mg | $25 | 2024-03-01 | Buy |
| Cayman Chemical | 90055 | (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% | 5mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 90055 | (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% | 10mg | $186 | 2024-03-01 | Buy |
| Cayman Chemical | 90055 | (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide ≥95% | 50mg | $807 | 2024-03-01 | Buy |
| Sigma-Aldrich | M1438 | (±)-2-Methylarachidonoyl-2′-fluoroethylamide ≥95%, ethanol solution | 5mg | $243 | 2024-03-01 | Buy |
Properties
Boiling point :503.6±50.0 °C(Predicted)
Density :0.921±0.06 g/cm3(Predicted)
Flash point :14 °C
storage temp. :−20°C
solubility :DMF: >10 mg/ml; DMSO: >30 mg/ml; Ethanol: >100 mg/ml; Ethanol:PBS (1:2): 8.5 mg/ml; PBS (pH 7.2): <100 μg/ml
pka :14.98±0.46(Predicted)
form :ethanol solution
Density :0.921±0.06 g/cm3(Predicted)
Flash point :14 °C
storage temp. :−20°C
solubility :DMF: >10 mg/ml; DMSO: >30 mg/ml; Ethanol: >100 mg/ml; Ethanol:PBS (1:2): 8.5 mg/ml; PBS (pH 7.2): <100 μg/ml
pka :14.98±0.46(Predicted)
form :ethanol solution
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
(±)-2-Methyl arachidonoyl-2'-fluoroethylamide (2-Methyl-2'-fluoro AEA) is an analog of anandamide (AEA) in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution confers considerably increased binding affinity for the CB1 receptor (Ki = 5.7 nM in rat brain). It also confers additional selectivity, in that binding to CB2 is decreased relative to AEA. However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme. 2-Methyl-2'-fluoro AEA is further modified by the addition of an α-methyl group at the C-2 position of arachidonic acid. This substitution confers enhanced metabolic stability. 2-Methyl-2'-fluoro AEA can fully substitute for Δ9-THC in animal self-administration tests, whereas AEA and 2-fluoro AEA cannot.Related product price
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