ONO-4059
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- $44 - $1700
- Product name: ONO-4059
- CAS: 1351635-67-0
- MF: C25H24N6O3
- MW: 456.5
- EINECS:-0
- MDL Number:MFCD29049511
- Synonyms:ONO-4059 (ONO-WG-307);GS-4059;ONO-4059 (analog);ONO-4059;(R)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one;ONO-4059 analog(GS-4059 analog);6-Amino-7,9-dihydro-9-[(3S)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-7-(4-phenoxyphenyl)-8H-purin-8-one;ONO-4059 analogue
17 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1514EB
- Product descriptionONO-4059analog
- Packaging5mg
- Price$276
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5941
- Product descriptionONO-4059
- Packaging5mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5941
- Product descriptionONO-4059
- Packaging10mg
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5941
- Product descriptionONO-4059
- Packaging25mg
- Price$504
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5941
- Product descriptionONO-4059
- Packaging50mg
- Price$866
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5941
- Product descriptionONO-4059
- Packaging100mg
- Price$1251
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18924
- Product descriptionONO-4059 analog ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18924
- Product descriptionONO-4059 analog ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18924
- Product descriptionONO-4059 analog ≥98%
- Packaging10mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18924
- Product descriptionONO-4059 analog ≥98%
- Packaging25mg
- Price$479
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM243943
- Product description(S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one 98%
- Packaging10mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM243943
- Product description(S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one 98%
- Packaging50mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM243943
- Product description(S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one 98%
- Packaging100mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5044
- Product descriptionONO-4059analog 99.76%
- Packaging25mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003781
- Product descriptionONO-4059analog 98+%
- Packaging100mg
- Price$530
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10044
- Product descriptionONO4059analog >98%
- Packaging250mg
- Price$900
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1514EB | ONO-4059analog | 5mg | $276 | 2021-12-16 | Buy |
| ApexBio Technology | B5941 | ONO-4059 | 5mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B5941 | ONO-4059 | 10mg | $284 | 2021-12-16 | Buy |
| ApexBio Technology | B5941 | ONO-4059 | 25mg | $504 | 2021-12-16 | Buy |
| ApexBio Technology | B5941 | ONO-4059 | 50mg | $866 | 2021-12-16 | Buy |
| ApexBio Technology | B5941 | ONO-4059 | 100mg | $1251 | 2021-12-16 | Buy |
| Cayman Chemical | 18924 | ONO-4059 analog ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 18924 | ONO-4059 analog ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 18924 | ONO-4059 analog ≥98% | 10mg | $257 | 2024-03-01 | Buy |
| Cayman Chemical | 18924 | ONO-4059 analog ≥98% | 25mg | $479 | 2024-03-01 | Buy |
| Chemenu | CM243943 | (S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one 98% | 10mg | $129 | 2021-12-16 | Buy |
| Chemenu | CM243943 | (S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one 98% | 50mg | $360 | 2021-12-16 | Buy |
| Chemenu | CM243943 | (S)-9-(1-acryloylpiperidin-3-yl)-6-amino-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one 98% | 100mg | $520 | 2021-12-16 | Buy |
| ChemScene | CS-5044 | ONO-4059analog 99.76% | 25mg | $420 | 2021-12-16 | Buy |
| Crysdot | CD31003781 | ONO-4059analog 98+% | 100mg | $530 | 2021-12-16 | Buy |
| DC Chemicals | DC10044 | ONO4059analog >98% | 250mg | $900 | 2021-12-16 | Buy |
Properties
Boiling point :714.0±70.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :3.15±0.20(Predicted)
color :White to off-white
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :3.15±0.20(Predicted)
color :White to off-white
Safety Information
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| Signal word: | Danger | |||||||
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Description
ONO-4059 analog is the [(3S)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl] analog of the recently published structure of ONO-4059. ONO-4059 is an orally bioavailable inhibitor of Bruton’s tyrosine kinase (BTK; IC50 = 2.2 nM), a non-receptor tyrosine kinase involved in signal transduction pathways regulating the proliferation, activation, and differentiation of B cells. ONO-4059 reversibly blocks B cell receptor signaling and B cell proliferation and activation. ONO-4059 suppresses the generation of inflammatory chemokines and cytokines in a mouse model of collagen-induced arthritis, resulting in regression of cartilage erosion, bone damage, and pannus formation. ONO-4059 is in clinical trials concerning certain leukemias and lymphomas, including chronic lymphocytic leukemia. The actions of ONO-4059 analog have not been studied.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
