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ChemicalBook >> CAS DataBase List >> Orantinib (SU6668)

Orantinib (SU6668)

Orantinib (SU6668) price.
  • $31 - $2097.8
  • Product name: Orantinib (SU6668)
  • CAS: 252916-29-3
  • MF: C18H18N2O3
  • MW: 310.35
  • EINECS:
  • MDL Number:MFCD03426212
  • Synonyms:3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid;TSU-68;5-[1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid;(Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid;TSU-68 (SU6668);1H-Pyrrole-3-propanoic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-;SU 6668(TSU-68);(E)-3-(2,4-diMethyl-5-((2-oxoindolin-3-ylidene)Methyl)-1H-pyrrol-3-yl)propanoic acid
19 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-O0202-M025
  • Product descriptionOrantinib ≥98%(HPLC)
  • Packaging25mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5331
  • Product descriptionTSU-68(SU6668,Orantinib)
  • Packaging10mg
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5331
  • Product descriptionTSU-68(SU6668,Orantinib)
  • Packaging50mg
  • Price$1290
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60314
  • Product descriptionOrantinib(SU6668) ≥98%
  • Packaging10mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146256
  • Product descriptionOrantinib (TSU-68) >98%
  • Packaging100mg
  • Price$542.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146256
  • Product descriptionOrantinib (TSU-68) >98%
  • Packaging250mg
  • Price$1060.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146256
  • Product descriptionOrantinib (TSU-68) >98%
  • Packaging1g
  • Price$2097.8
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13873
  • Product descriptionSU 6668 ≥98%
  • Packaging10mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13873
  • Product descriptionSU 6668 ≥98%
  • Packaging5mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13873
  • Product descriptionSU 6668 ≥98%
  • Packaging1mg
  • Price$31
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM148996
  • Product description(E)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid 95%+
  • Packaging100mg
  • Price$412
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0197
  • Product descriptionOrantinib 98.80%
  • Packaging100mg
  • Price$756
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002508
  • Product descriptionTSU-68 98+%
  • Packaging100mg
  • Price$441
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002508
  • Product descriptionTSU-68 98+%
  • Packaging50mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002508
  • Product descriptionTSU-68 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC5079
  • Product descriptionOrantinib(TSU-68) >98%
  • Packaging1g
  • Price$1400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-O0202-M025 Orantinib ≥98%(HPLC) 25mg $259 2021-12-16 Buy
ApexBio Technology A5331 TSU-68(SU6668,Orantinib) 10mg $314 2021-12-16 Buy
ApexBio Technology A5331 TSU-68(SU6668,Orantinib) 50mg $1290 2021-12-16 Buy
Arctom CFN60314 Orantinib(SU6668) ≥98% 10mg $208 2021-12-16 Buy
Biorbyt Ltd orb146256 Orantinib (TSU-68) >98% 100mg $542.3 2021-12-16 Buy
Biorbyt Ltd orb146256 Orantinib (TSU-68) >98% 250mg $1060.8 2021-12-16 Buy
Biorbyt Ltd orb146256 Orantinib (TSU-68) >98% 1g $2097.8 2021-12-16 Buy
Cayman Chemical 13873 SU 6668 ≥98% 10mg $121 2024-03-01 Buy
Cayman Chemical 13873 SU 6668 ≥98% 5mg $73 2024-03-01 Buy
Cayman Chemical 13873 SU 6668 ≥98% 1mg $31 2024-03-01 Buy
Chemenu CM148996 (E)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoicacid 95%+ 100mg $412 2021-12-16 Buy
ChemScene CS-0197 Orantinib 98.80% 100mg $756 2021-12-16 Buy
Crysdot CD31002508 TSU-68 98+% 100mg $441 2021-12-16 Buy
Crysdot CD31002508 TSU-68 98+% 50mg $234 2021-12-16 Buy
Crysdot CD31002508 TSU-68 98+% 10mg $59 2021-12-16 Buy
DC Chemicals DC5079 Orantinib(TSU-68) >98% 1g $1400 2021-12-16 Buy

Properties

Melting point :252-254 °C
Boiling point :590.5±50.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :4?+-.0.10(Predicted)
color :Orange to Brown

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SU 6668 is an inhibitor of the receptor tyrosine kinases PDGFRβ, VEGFR2, and FGFR1 (IC50 = 0.06, 2.4, and 3.0 μM, respectively) but not EGFR (IC50 >100 μM). Through these actions, SU 6668 suppresses tumor growth, blocks angiogenesis in tumors, and induces apoptosis of tumor vasculature and regression of established tumors. It also inhibits metastasis in a mouse orthotopic model of melanoma. SU 6668 also inhibits Aurora kinases B and C (IC50 = 35 and 210 nM, respectively) and may target other kinases.

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