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ChemicalBook >> CAS DataBase List >> PAC-1-d8

PAC-1-d8

PAC-1-d8 price.
  • $503.67 - $990
  • Product name: PAC-1-d8
  • CAS: 1287241-26-2
  • MF: C23H28N4O2
  • MW: 392.49402
  • EINECS:
  • MDL Number:
  • Synonyms:PAC-1-d8;YQNRVGJCPCNMKT-SRNXAORYSA-N;[2H8]-PAC-1
2 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • TRC
Package
  • 5MG
  • 25mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0014654
  • Product descriptionPAC-1-D8 95.00%
  • Packaging5MG
  • Price$503.67
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP132002
  • Product descriptionPAC-1-d8
  • Packaging25mg
  • Price$990
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation RDL0014654 PAC-1-D8 95.00% 5MG $503.67 2021-12-16 Buy
TRC P132002 PAC-1-d8 25mg $990 2021-12-16 Buy

Properties

solubility :soluble in DMSO, Methanol
form :Solid
color :Off-White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Labelled PAC-1 is a caspase 3 activator. Caspase activation is a key strategy in cancer therapy. Caspase 3 is a key executioner caspase and direct effector of apoptosis. Hallmark of many cancers is the circumvention of signal in the activation of executioner caspases and loss of apoptotic response. EC50 for caspase 3 activation = 0.33 μM and caspase 7= 4.5 μM. The IC50 for apoptosis induction = 0.92 μM. Elevated caspase 3 level in cancerous cell lines and tissues allows PAC-1 to selectively induce apoptosis in tissues.