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ChemicalBook >> CAS DataBase List >> PB28dihydrochloride

PB28dihydrochloride

PB28dihydrochloride price.
  • $132 - $1073.29
  • Product name: PB28dihydrochloride
  • CAS: 172906-90-0
  • MF: C24H38N2O
  • MW: 370.57
  • EINECS:
  • MDL Number:MFCD06798349
  • Synonyms:1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazinedihydrochloride;PB-28;Piperazine,1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]-;PB28 dihydrochloride >=98% (HPLC), solid
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Sigma-Aldrich
  • TRC
Package
  • 2.5mg
  • 5mg
  • 10MG
  • 50MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004726
  • Product descriptionPB-28 95.00%
  • Packaging10MG
  • Price$665.81
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004726
  • Product descriptionPB-28 95.00%
  • Packaging50MG
  • Price$1073.29
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP9246
  • Product descriptionPB28 dihydrochloride ≥98% (HPLC), solid
  • Packaging5mg
  • Price$132
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP215100
  • Product descriptionPB28
  • Packaging2.5mg
  • Price$215
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0004726 PB-28 95.00% 10MG $665.81 2021-12-16 Buy
American Custom Chemicals Corporation API0004726 PB-28 95.00% 50MG $1073.29 2021-12-16 Buy
Sigma-Aldrich P9246 PB28 dihydrochloride ≥98% (HPLC), solid 5mg $132 2024-03-01 Buy
TRC P215100 PB28 2.5mg $215 2021-12-16 Buy

Properties

Boiling point :501.4±50.0 °C(Predicted)
Density :1.032±0.06 g/cm3(Predicted)
storage temp. :Desiccate at +4°C
solubility :H2O: ~10mg/mL at 60°C
pka :8.32±0.70(Predicted)
form :solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PB 28 dihydrochloride is a high affinity selective σ2 receptor Activators (Ki values are 0.8 and 15.2 nM for σ2 and σ1 receptors respectively) that displays minimal affinity at other receptors. PB 28 dihydrochloride inhibits electrically evoked twitch in guinea pig bladder and ileum (EC50 values are 2.62 and 3.96 μM respectively). PB 28 dihydrochloride also displays antiproliferative and cytotoxic effects in SK-N-SH neuroblastoma and C6 glioma cells.

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Suppliers and manufacturers

Hangzhou MolCore BioPharmatech Co.,Ltd.
Aladdin Scientific Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. EMMX Biotechnology LLC Beijing Jin Ming Biotechnology Co., Ltd. Energy Chemical Beijing Jin Ming Biotechnology Co., Ltd. Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. Olix (Shanghai) Pharmaceutical Technology Co., Ltd