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ChemicalBook >> CAS DataBase List >> PBTZ169

PBTZ169

PBTZ169 price.
  • $32 - $1140
  • Product name: PBTZ169
  • CAS: 1377239-83-2
  • MF: C20H23F3N4O3S
  • MW: 456.48
  • EINECS:
  • MDL Number:
  • Synonyms:2-(4-(Cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-trifluoromethyl-4H-1,3-benzothiazin-4-one;Macozinone;PBTZ169;PBTZ-169;PBTZ 169;CS-2309;PBTZ169 (PBTZ 169; 2-[4-(Cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one;4H-1,3-Benzothiazin-4-one, 2-[4-(cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-;2-(4-(Cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one
16 prices
Selected condition:
Brand
  • AK Scientific
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 2x5mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number3274DN
  • Product descriptionMacozinone
  • Packaging5mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2626
  • Product descriptionPBTZ169 100%
  • Packaging2x5mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22202
  • Product descriptionPBTZ169 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22202
  • Product descriptionPBTZ169 ≥98%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22202
  • Product descriptionPBTZ169 ≥98%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22202
  • Product descriptionPBTZ169 ≥98%
  • Packaging25mg
  • Price$533
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5777
  • Product descriptionMacozinone 99.13%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5777
  • Product descriptionMacozinone 99.13%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5777
  • Product descriptionMacozinone 99.13%
  • Packaging50mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5777
  • Product descriptionMacozinone 99.13%
  • Packaging100mg
  • Price$1140
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11269390
  • Product descriptionPBTZ169 97%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11269390
  • Product descriptionPBTZ169 97%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11269390
  • Product descriptionPBTZ169 97%
  • Packaging50mg
  • Price$455
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11269390
  • Product descriptionPBTZ169 97%
  • Packaging100mg
  • Price$665
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9723
  • Product descriptionPBTZ169 >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP216563
  • Product descriptionPBTZ169
  • Packaging5mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3274DN Macozinone 5mg $252 2021-12-16 Buy
Axon Medchem Axon2626 PBTZ169 100% 2x5mg $165 2021-12-16 Buy
Cayman Chemical 22202 PBTZ169 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 22202 PBTZ169 ≥98% 5mg $139 2024-03-01 Buy
Cayman Chemical 22202 PBTZ169 ≥98% 10mg $243 2024-03-01 Buy
Cayman Chemical 22202 PBTZ169 ≥98% 25mg $533 2024-03-01 Buy
ChemScene CS-5777 Macozinone 99.13% 5mg $144 2021-12-16 Buy
ChemScene CS-5777 Macozinone 99.13% 10mg $240 2021-12-16 Buy
ChemScene CS-5777 Macozinone 99.13% 50mg $780 2021-12-16 Buy
ChemScene CS-5777 Macozinone 99.13% 100mg $1140 2021-12-16 Buy
Crysdot CD11269390 PBTZ169 97% 5mg $84 2021-12-16 Buy
Crysdot CD11269390 PBTZ169 97% 10mg $140 2021-12-16 Buy
Crysdot CD11269390 PBTZ169 97% 50mg $455 2021-12-16 Buy
Crysdot CD11269390 PBTZ169 97% 100mg $665 2021-12-16 Buy
DC Chemicals DC9723 PBTZ169 >98% 100mg $400 2021-12-16 Buy
TRC P216563 PBTZ169 5mg $140 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:4.6(Max Conc. mg/mL);10.1(Max Conc. mM)
form :A crystalline solid
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PBTZ169 is an antibiotic with antimycobacterial activity. It is an irreversible inhibitor of DprE1, an essential enzyme for cell wall synthesis in mycobacteria. PBTZ169 is active against M. tuberculosis in vitro (MIC = ≤0.19 ng/ml) without inducing cytotoxicity in Vero cells when used at concentrations up to 125 μM. It reduces the bacterial burden in the lung and spleen in a mouse model of chronic tuberculosis when administered at a dose of 50 mg/kg per day.