PD 166285
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- $118 - $2000
- Product name: PD 166285
- CAS: 212391-63-4
- MF: C26H29Cl4N5O2
- MW: 585.37
- EINECS:
- MDL Number:MFCD18086890
- Synonyms:6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one Hydrochloride;PD 166285;6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-onedihydrochloride;PD 166285 dihydrochloride;6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylaMino-ethoxy)-phenylaMino]-8-Methyl-8H-pyrido[2,3-d]pyriMidin-7-one hydrochloride;6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimi;6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylaMino)ethoxy]phenyl]aMino]-8-Methylpyrido[2,3-d]pyriMidin-7(8H)-one;PD 166285 - CAS 212391-63-4 - Calbiochem
17 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1
- 2mg
- 5mg
- 10mg
- 25mg
- 50MG
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4197CR
- Product description6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
- Packaging2mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4197CR
- Product description6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride
- Packaging5mg
- Price$387
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000178
- Product descriptionPD-166285 95.00%
- Packaging5MG
- Price$786.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000178
- Product descriptionPD-166285 95.00%
- Packaging50MG
- Price$1963.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging2mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging50mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP26776
- Product descriptionPD 166285
- Packaging25mg
- Price$1250
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC21466
- Product descriptionPD166285 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC21466
- Product descriptionPD166285 >98%
- Packaging250mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC21466
- Product descriptionPD166285 >98%
- Packaging1g
- Price$2000
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number513028
- Product descriptionPD 166285 - CAS 212391-63-4 - Calbiochem
A cell-permeable, orally bioavailable, ATP-competitive, broad-spectrum tyrosine kinase inhibitor that suppresses angiogenesis both in vitro and in vivo. - Packaging5mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number3785
- Product descriptionPD166285dihydrochloride ≥99%(HPLC)
- Packaging1
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP217500
- Product descriptionPD-166285
- Packaging25mg
- Price$565
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number019157
- Product descriptionPD-166285
- Packaging5mg
- Price$460
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4197CR | 6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride | 2mg | $239 | 2021-12-16 | Buy |
| AK Scientific | 4197CR | 6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one;dihydrochloride | 5mg | $387 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000178 | PD-166285 95.00% | 5MG | $786.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000178 | PD-166285 95.00% | 50MG | $1963.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP26776 | PD 166285 | 2mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP26776 | PD 166285 | 5mg | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP26776 | PD 166285 | 10mg | $400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP26776 | PD 166285 | 50mg | $600 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FP26776 | PD 166285 | 25mg | $1250 | 2021-12-16 | Buy |
| DC Chemicals | DC21466 | PD166285 >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC21466 | PD166285 >98% | 250mg | $1000 | 2021-12-16 | Buy |
| DC Chemicals | DC21466 | PD166285 >98% | 1g | $2000 | 2021-12-16 | Buy |
| Sigma-Aldrich | 513028 | PD 166285 - CAS 212391-63-4 - Calbiochem A cell-permeable, orally bioavailable, ATP-competitive, broad-spectrum tyrosine kinase inhibitor that suppresses angiogenesis both in vitro and in vivo. |
5mg | $216 | 2024-03-01 | Buy |
| Tocris | 3785 | PD166285dihydrochloride ≥99%(HPLC) | 1 | $118 | 2021-12-16 | Buy |
| TRC | P217500 | PD-166285 | 25mg | $565 | 2021-12-16 | Buy |
| Usbiological | 019157 | PD-166285 | 5mg | $460 | 2021-12-16 | Buy |
Properties
Melting point :239-242?C
storage temp. :Desiccate at RT
solubility :DMSO, Methanol
form :Pale yellow solid
color :Yellow
Stability :Hygroscopic
storage temp. :Desiccate at RT
solubility :DMSO, Methanol
form :Pale yellow solid
color :Yellow
Stability :Hygroscopic
Safety Information
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Description
PD 166285 is a potent inhibitor of the tyrosine kinases c-Src, Flg (fibroblast growth factor receptor 1, FGFR1), and PDGFRβ (platelet-derived growth factor receptor β) (IC50 values are 8.4, 39.3 and 98.3 nM respectively). PD 166285 also inhibits the checkpoint kinases Wee1 and MYT1 (Myt1), abolishes Cdc2 phosphorylation in numerous tumor cell lines, and abrogates the G2 checkpoint. PD 166285 is an RTK inhibitor with broad-spectrum properties and displays anti-angiogenic activity and anti-tumor efficacy when used with PDT (photodynamic therapy). PD 166285 is an inhibitor of EGFR.More related product prices
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