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ChemicalBook >> CAS DataBase List >> PF 04418948

PF 04418948

PF 04418948 price.
  • $48 - $2200
  • Product name: PF 04418948
  • CAS: 1078166-57-0
  • MF: C23H20FNO5
  • MW: 409.41
  • EINECS:
  • MDL Number:MFCD24387541
  • Synonyms:1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid;PF 04418948;1-(4-FLUOROBENZOYL)-3-[(6-METHOXYNAPHTHALEN-2-YL)OXYMETHYL]AZETIDINE-3-CARBOXYLIC ACID;PF-04418948;PF04418948;PF 04418948;CS-2852;PF-0441848;PF04418948; PF 04418948;3-Azetidinecarboxylic acid, 1-(4-fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-
24 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 50
  • 5mg
  • 10
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2831DC
  • Product descriptionPF-04418948
  • Packaging10mg
  • Price$262
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging5mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging25mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging50mg
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging100mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging250mg
  • Price$705
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA920639
  • Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
  • Packaging1g
  • Price$1762
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5726
  • Product descriptionPF04418948
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5726
  • Product descriptionPF04418948
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15016
  • Product descriptionPF-04418948 ≥98%
  • Packaging5mg
  • Price$98
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15016
  • Product descriptionPF-04418948 ≥98%
  • Packaging10mg
  • Price$146
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15016
  • Product descriptionPF-04418948 ≥98%
  • Packaging50mg
  • Price$680
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15016
  • Product descriptionPF-04418948 ≥98%
  • Packaging100mg
  • Price$964
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5011
  • Product descriptionPF-04418948 99.22%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5011
  • Product descriptionPF-04418948 99.22%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2831DC PF-04418948 10mg $262 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 5mg $48 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 10mg $75 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 25mg $158 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 50mg $272 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 100mg $353 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 250mg $705 2021-12-16 Buy
Ambeed A920639 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% 1g $1762 2021-12-16 Buy
ApexBio Technology B5726 PF04418948 10mg $85 2021-12-16 Buy
ApexBio Technology B5726 PF04418948 50mg $350 2021-12-16 Buy
Cayman Chemical 15016 PF-04418948 ≥98% 5mg $98 2024-03-01 Buy
Cayman Chemical 15016 PF-04418948 ≥98% 10mg $146 2024-03-01 Buy
Cayman Chemical 15016 PF-04418948 ≥98% 50mg $680 2024-03-01 Buy
Cayman Chemical 15016 PF-04418948 ≥98% 100mg $964 2024-03-01 Buy
ChemScene CS-5011 PF-04418948 99.22% 5mg $70 2021-12-16 Buy
ChemScene CS-5011 PF-04418948 99.22% 10mg $110 2021-12-16 Buy

Properties

Melting point :171-172°C
Boiling point :639.1±55.0 °C(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.25±0.20(Predicted)
color :white to beige
InChIKey :POJZIZBONPAWIV-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Prostaglandin E2 (PGE2) evokes distinct responses through four different ‘E prostanoid’ (EP) receptors. EP2 is a G protein-coupled receptor which signals preferentially through Gs proteins. PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). It is over a thousand-fold less active at other prostanoid receptors, including other EP receptors. PF-04418948 can be used in cells and tissues. In rats, it significantly reduces the effects of the EP2-selective agonist butaprost on cutaneous blood flow when given orally.

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