PHA-793887
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- $43 - $9556.47
- Product name: PHA-793887
- CAS: 718630-59-2
- MF: C19H31N5O2
- MW: 361.48
- EINECS:
- MDL Number:MFCD17169992
- Synonyms:3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;PHA-793887;N-(6,6-dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide PHA-793887;PHA-793887 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide;PHA-793887;PHA793887;3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c];PHA-793887 USP/EP/BP
27 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1MG
- 5MG
- 10mg
- 25mg
- 50MG
- 100mg
- 250mg
- 1G
- ManufacturerAK Scientific
- Product numberX7380
- Product descriptionPHA-793887
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000927
- Product descriptionN-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000927
- Product descriptionN-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00%
- Packaging5MG
- Price$927.47
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000927
- Product descriptionN-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00%
- Packaging10MG
- Price$1127.86
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000927
- Product descriptionN-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00%
- Packaging50MG
- Price$2946.98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000927
- Product descriptionN-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00%
- Packaging1G
- Price$9556.47
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5459
- Product descriptionPHA-793887
- Packaging25mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180756
- Product descriptionPHA-793887 >99%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180756
- Product descriptionPHA-793887 >99%
- Packaging250mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180756
- Product descriptionPHA-793887 >99%
- Packaging1g
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM145343
- Product descriptionPHA 793887
- Packaging10mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFM145343
- Product descriptionPHA 793887
- Packaging50mg
- Price$612.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18388
- Product descriptionPHA-793887 ≥95%
- Packaging1mg
- Price$43
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number18388
- Product descriptionPHA-793887 ≥95%
- Packaging5mg
- Price$46
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18388
- Product descriptionPHA-793887 ≥95%
- Packaging10mg
- Price$88
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18388
- Product descriptionPHA-793887 ≥95%
- Packaging50mg
- Price$230
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X7380 | PHA-793887 | 10mg | $180 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000927 | N-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000927 | N-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00% | 5MG | $927.47 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000927 | N-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00% | 10MG | $1127.86 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000927 | N-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00% | 50MG | $2946.98 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000927 | N-(6,6-DIMETHYL-5-[(1-METHYLPIPERIDIN-4-YL)CARBONYL]-1H,4H,5H,6H-PYRROLO[3,4-C]PYRAZOL-3-YL)-3-METHYLBUTANAMIDE 95.00% | 1G | $9556.47 | 2021-12-16 | Buy |
| ApexBio Technology | A5459 | PHA-793887 | 25mg | $300 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180756 | PHA-793887 >99% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180756 | PHA-793887 >99% | 250mg | $1133.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180756 | PHA-793887 >99% | 1g | $2245.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM145343 | PHA 793887 | 10mg | $175 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FM145343 | PHA 793887 | 50mg | $612.5 | 2021-12-16 | Buy |
| Cayman Chemical | 18388 | PHA-793887 ≥95% | 1mg | $43 | 2023-06-20 | Buy |
| Cayman Chemical | 18388 | PHA-793887 ≥95% | 5mg | $46 | 2024-03-01 | Buy |
| Cayman Chemical | 18388 | PHA-793887 ≥95% | 10mg | $88 | 2024-03-01 | Buy |
| Cayman Chemical | 18388 | PHA-793887 ≥95% | 50mg | $230 | 2024-03-01 | Buy |
Properties
Melting point :>147°C (dec.)
Boiling point :596.2±50.0 °C(Predicted)
Density :1.176±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol(Slightly)
pka :13.74±0.40(Predicted)
form :Solid
color :Off-White to Pale Yellow
Stability :Hygroscopic
Boiling point :596.2±50.0 °C(Predicted)
Density :1.176±0.06 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol(Slightly)
pka :13.74±0.40(Predicted)
form :Solid
color :Off-White to Pale Yellow
Stability :Hygroscopic
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | |||||||
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Description
PHA-793887 is a pyrrolo[3,4-c]pyrazole that inhibits cyclin-dependent kinases Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk7/cyclin H with IC50 values of 8, 8, 5, and 10 nM, respectively. It is more than 6-fold selective for these kinases over Cdk1/cyclin B, Cdk4/cyclin D1, Cdk9/cyclin T, and GSK3β (IC50s = 60, 62, 138, and 79 nM, respectively). PHA-793887 is cytotoxic to human ovarian A2780, colon HCT-116, pancreatic BX-PC3, and leukemic K562, KU812, KCL22, and TOM1 cells both in vitro and in xenograft models. This compound has been examined in patients with solid tumors in phase 1 clinical trials.More related product prices
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carboxamide
$28-4644
Suppliers and manufacturers
Hubei xin bonus chemical co. LTD
CONIER CHEM AND PHARMA LIMITED
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Dideu Industries Group Limited
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InvivoChem
Hunan Jibang Biological Technology Co., LTD
LEAP CHEM CO., LTD.
![3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide](https://img.chemicalbook.com/ProductImageEN/2020-1/small/41c31098-330f-4f89-a4c8-db449616603e.jpg){kind=small}