PROTEIN C
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- $247 - $606
- Product name: PROTEIN C
- CAS: 42617-41-4
- MF:
- MW: 0
- EINECS:
- MDL Number:MFCD00165567
- Synonyms:PROTEIN C, ACTIVATED, HUMAN;PROTEIN C;PROTEIN C, ACTIVATED;PROTEIN C, HUMAN PLASMA;PROTEIN C CONTROL PLASMA;PROTEIN C, HUMAN;PROTEIN C, ACTIVATED, HUMAN PLASMA;HUMAN PROTEIN C
8 prices
Selected condition：
Brand
- Sigma-Aldrich
- Usbiological
Package
- 10ug
- 50ug
- 100ug
- 0.1mg
- 200ug
- 200μL
- ManufacturerSigma-Aldrich
- Product numberP2200
- Product descriptionProtein C from human plasma Activated, lyophilized powder, ≥90% (SDS-PAGE)
- Packaging0.1mg
- Price$606
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSAB4200594
- Product descriptionAnti-APC (C-terminal) antibody produced in rabbit ~1.0?mg/mL, affinity isolated antibody
- Packaging200μL
- Price$511
- Updated2024-03-01
- Buy
- ManufacturerUsbiological
- Product numberP9102-36
- Product descriptionProtein C
- Packaging100ug
- Price$247
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberP9081
- Product descriptionProtein C, Activated
- Packaging50ug
- Price$306
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number156494
- Product descriptionProtein C
- Packaging10ug
- Price$355
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number156495
- Product descriptionProtein C
- Packaging10ug
- Price$359
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number156493
- Product descriptionProtein C
- Packaging10ug
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberP9102-33A
- Product descriptionProtein C
- Packaging200ug
- Price$495
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | P2200 | Protein C from human plasma Activated, lyophilized powder, ≥90% (SDS-PAGE) | 0.1mg | $606 | 2024-03-01 | Buy |
| Sigma-Aldrich | SAB4200594 | Anti-APC (C-terminal) antibody produced in rabbit ~1.0?mg/mL, affinity isolated antibody | 200μL | $511 | 2024-03-01 | Buy |
| Usbiological | P9102-36 | Protein C | 100ug | $247 | 2021-12-16 | Buy |
| Usbiological | P9081 | Protein C, Activated | 50ug | $306 | 2021-12-16 | Buy |
| Usbiological | 156494 | Protein C | 10ug | $355 | 2021-12-16 | Buy |
| Usbiological | 156495 | Protein C | 10ug | $359 | 2021-12-16 | Buy |
| Usbiological | 156493 | Protein C | 10ug | $360 | 2021-12-16 | Buy |
| Usbiological | P9102-33A | Protein C | 200ug | $495 | 2021-12-16 | Buy |
Properties
storage temp. :-20°C
solubility :H2O: 1 mg/mL
form :lyophilized powder
solubility :H2O: 1 mg/mL
form :lyophilized powder
Safety Information
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Description
Drotrecogin alfa was introduced in the US as a new intravenous treatment for the reduction of mortality in adult patients with severe sepsis associated with acute organ dysfunction. Drotrecogin aifa is the first recombinant activated protein C expressed in human kidney 293 cells. Activated protein C1 an endogenous serine protease, acts as an antithrombotic via inhibition of factor Va and Vllla, promotes fibrinolysis via inactivation of plasminogen-activator inhibitor-1 and exerts an anti-inflammatory effect by inhibiting the production of inflammatory cytokines (tumor necrosis factor-alpha, interieukin-1 and 6) by monocytes. It was shown that the majority of patients with sepsis have reduced levels of activated protein C. In a baboon model of lethal E. coli sepsis, administration of activated protein C reduced mortality. In a phase III clinical trial, intravenous infusion of drotrecogin alfa at a dose of 24 μg/kg/h over 96 h significantly reduced the risk of death compared with placebo in patients with severe sepsis. However, an increased risk of serious bleeding has been associated with the administration of the drug.Related product price
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