PTP Inhibitor V, PHPS1
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- $40 - $1134.53
- Product name: PTP Inhibitor V, PHPS1
- CAS: 314291-83-3
- MF: C21H15N5O6S
- MW: 465.44
- EINECS:
- MDL Number:MFCD01079012
- Synonyms:PHPS1 sodium salt hydrate;PTP Inhibitor V, PHPS1;PHPS1 sodium salt;PHPS1;4-[2-[1,5-dihydro-3-(4-nitrophenyl)-5-oxo-1-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-benzenesulfonic acid sodium salt hydrate;PTP Inhibitor V, PHPS1 - CAS 314291-83-3 - Calbiochem;Benzenesulfonic acid, 4-[2-[1,5-dihydro-3-(4-nitrophenyl)-5-oxo-1-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-;4-(2-(3-(4-Nitrophenyl)-5-oxo-1-phenyl-1H-pyrazol-4(5H)-ylidene)hydrazinyl)benzenesulfonic acid
9 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- Sigma-Aldrich
- Tocris
Package
- 25
- 1mg
- 5MG
- 10mg
- 25MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008596
- Product descriptionPHPS-1 SODIUM SALT HYDRATE 95.00%
- Packaging5MG
- Price$728
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008596
- Product descriptionPHPS-1 SODIUM SALT HYDRATE 95.00%
- Packaging25MG
- Price$1134.53
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18856
- Product descriptionPHPS1 ≥98%
- Packaging1mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18856
- Product descriptionPHPS1 ≥98%
- Packaging5mg
- Price$129
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18856
- Product descriptionPHPS1 ≥98%
- Packaging10mg
- Price$178
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number540213
- Product descriptionPTP Inhibitor V, PHPS1
- Packaging10mg
- Price$187
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0039
- Product descriptionPHPS1 sodium salt hydrate ≥98% (HPLC)
- Packaging5mg
- Price$211
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0039
- Product descriptionPHPS1 sodium salt hydrate ≥98% (HPLC)
- Packaging25mg
- Price$735
- Updated2022-05-15
- Buy
- ManufacturerTocris
- Product number6771
- Product descriptionPHPS1sodiumsalt ≥98%(HPLC)
- Packaging25
- Price$624
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0008596 | PHPS-1 SODIUM SALT HYDRATE 95.00% | 5MG | $728 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008596 | PHPS-1 SODIUM SALT HYDRATE 95.00% | 25MG | $1134.53 | 2021-12-16 | Buy |
| Cayman Chemical | 18856 | PHPS1 ≥98% | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 18856 | PHPS1 ≥98% | 5mg | $129 | 2024-03-01 | Buy |
| Cayman Chemical | 18856 | PHPS1 ≥98% | 10mg | $178 | 2024-03-01 | Buy |
| Sigma-Aldrich | 540213 | PTP Inhibitor V, PHPS1 | 10mg | $187 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0039 | PHPS1 sodium salt hydrate ≥98% (HPLC) | 5mg | $211 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0039 | PHPS1 sodium salt hydrate ≥98% (HPLC) | 25mg | $735 | 2022-05-15 | Buy |
| Tocris | 6771 | PHPS1sodiumsalt ≥98%(HPLC) | 25 | $624 | 2021-12-16 | Buy |
Properties
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
pka :-2.90±0.40(Predicted)
form :solid
color :red
InChI :InChI=1S/C21H15N5O6S/c27-21-20(23-22-15-8-12-18(13-9-15)33(30,31)32)19(14-6-10-17(11-7-14)26(28)29)24-25(21)16-4-2-1-3-5-16/h1-13,22H,(H,30,31,32)
InChIKey :VIQSBJOMLQLAKC-UHFFFAOYSA-N
SMILES :C1(S(O)(=O)=O)=CC=C(NN=C2C(=O)N(C3=CC=CC=C3)N=C2C2=CC=C([N+]([O-])=O)C=C2)C=C1
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
pka :-2.90±0.40(Predicted)
form :solid
color :red
InChI :InChI=1S/C21H15N5O6S/c27-21-20(23-22-15-8-12-18(13-9-15)33(30,31)32)19(14-6-10-17(11-7-14)26(28)29)24-25(21)16-4-2-1-3-5-16/h1-13,22H,(H,30,31,32)
InChIKey :VIQSBJOMLQLAKC-UHFFFAOYSA-N
SMILES :C1(S(O)(=O)=O)=CC=C(NN=C2C(=O)N(C3=CC=CC=C3)N=C2C2=CC=C([N+]([O-])=O)C=C2)C=C1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||
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Description
PHPS1 is a cell-permeable, phosphotyrosine mimetic that inhibits the Src homology region 2 domain-containing phosphatase (SHP)-2 (IC50 = 2.1 μM; Ki = 0.73 μM). It is selective for SHP-2, inhibiting ECPTP, PTP1B, SHP-1, and mycobacterium MptpA at relatively higher concentrations (IC50s = 5.4, 19, 30, and 39 μM, respectively). PHPS1 has been shown to inhibit SHP-2-dependent cellular signaling and tumor cell colony formation.Suppliers and manufacturers
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