Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> PU-WS13

PU-WS13

PU-WS13 price.
  • $36 - $2500
  • Product name: PU-WS13
  • CAS: 1454619-14-7
  • MF: C17H20Cl2N6S
  • MW: 411.35
  • EINECS:-0
  • MDL Number:MFCD28156414
  • Synonyms:PU-WS13;8-((3,5-dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine;6-Amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine;8-(3,5-dichlorophenyl)sulfanyl-9-[3-(propan-2-ylamino)propyl]purin-6-amine;PU WS13;PUWS13;CS-1689;CS-2047;9H-Purine-9-propanamine, 6-amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-
21 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX3561
  • Product description8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA451894
  • Product descriptionPu-ws13 98+%
  • Packaging5mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA451894
  • Product descriptionPu-ws13 98+%
  • Packaging10mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5885
  • Product descriptionPU-WS13
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5885
  • Product descriptionPU-WS13
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5885
  • Product descriptionPU-WS13
  • Packaging50mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18409
  • Product descriptionPU-WS13 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number18409
  • Product descriptionPU-WS13 ≥98%
  • Packaging5mg
  • Price$91
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number18409
  • Product descriptionPU-WS13 ≥98%
  • Packaging10mg
  • Price$143
  • Updated2022-04-27
  • Buy
  • ManufacturerCayman Chemical
  • Product number18409
  • Product descriptionPU-WS13 ≥98%
  • Packaging25mg
  • Price$269
  • Updated2022-04-27
  • Buy
  • ManufacturerChemenu
  • Product numberCM294858
  • Product description8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine 98%
  • Packaging50mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4953
  • Product descriptionPU-WS13 99.34%
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4953
  • Product descriptionPU-WS13 99.34%
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4953
  • Product descriptionPU-WS13 99.34%
  • Packaging50mg
  • Price$672
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003427
  • Product descriptionPU-WS13 98+%
  • Packaging5mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003427
  • Product descriptionPU-WS13 98+%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X3561 8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine 1mg $147 2021-12-16 Buy
Ambeed A451894 Pu-ws13 98+% 5mg $97 2021-12-16 Buy
Ambeed A451894 Pu-ws13 98+% 10mg $153 2021-12-16 Buy
ApexBio Technology B5885 PU-WS13 5mg $90 2021-12-16 Buy
ApexBio Technology B5885 PU-WS13 10mg $140 2021-12-16 Buy
ApexBio Technology B5885 PU-WS13 50mg $610 2021-12-16 Buy
Cayman Chemical 18409 PU-WS13 ≥98% 1mg $36 2022-04-27 Buy
Cayman Chemical 18409 PU-WS13 ≥98% 5mg $91 2022-04-27 Buy
Cayman Chemical 18409 PU-WS13 ≥98% 10mg $143 2022-04-27 Buy
Cayman Chemical 18409 PU-WS13 ≥98% 25mg $269 2022-04-27 Buy
Chemenu CM294858 8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine 98% 50mg $403 2021-12-16 Buy
ChemScene CS-4953 PU-WS13 99.34% 5mg $108 2021-12-16 Buy
ChemScene CS-4953 PU-WS13 99.34% 10mg $156 2021-12-16 Buy
ChemScene CS-4953 PU-WS13 99.34% 50mg $672 2021-12-16 Buy
Crysdot CD31003427 PU-WS13 98+% 5mg $63 2021-12-16 Buy
Crysdot CD31003427 PU-WS13 98+% 10mg $100 2021-12-16 Buy

Properties

Boiling point :617.4±65.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :DMF: 30 mg/mL,DMSO: 30 mg/mL,DMSO:PBS(pH7.2) (1:1): 0.5 mg/mL,Ethanol: 25 mg/mL
form :Powder
pka :10.15±0.29(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Glucose-regulated protein 94 (Grp94) is a stress-inducible molecular chaperone belonging to the heat shock protein (Hsp) family and, as a result, is also known as Hsp90B1. Grp94 is essential for the processing of proteins that have been implicated in tumorigenesis, including insulin-like growth factor 1 (IGF-1), Toll-like receptors (TLRs), and integrins. It also functions in antigen presentation, and its secreted form can elicit innate and adaptive immune responses. PU-WS13 is a cell-permeable inhibitor of Grp94 (EC50 = 220 nM). It displays selectivity for Grp94 over the related Hsps Trap-1, Hsp90α, and Hsp90β. PU-WS13 blocks the proliferation of HER2 over-expressing SK-BR-3 cells in the sub-G1 phase and induces apoptosis, but doesn’t significantly affect the survival of normal cells. It induces both apoptosis and necrosis in multiple myeloma cells but does not induce death in pre-B leukemic cells. Unlike pan-Hsp90 inhibitors, PU-WS13 does not activate a feedback heat-shock response.