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ChemicalBook >> CAS DataBase List >> Ponatinib-d8

Ponatinib-d8

Ponatinib-d8 price.
  • $220 - $531
  • Product name: Ponatinib-d8
  • CAS: 1562993-37-6
  • MF: C29H27F3N6O
  • MW: 532.57
  • EINECS:
  • MDL Number:MFCD22380805
  • Synonyms:Ponatinib-d8;[2H8]-Ponatinib;AP24534 D8;Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-3-(trifluoromethyl)phenyl]-
3 prices
Selected condition:
Brand
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • ManufacturerCayman Chemical
  • Product number28905
  • Product descriptionPonatinib-d8
  • Packaging1mg
  • Price$354
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP688252
  • Product descriptionPonatinib-d8
  • Packaging1mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number462817
  • Product descriptionPonatinib-d8
  • Packaging1mg
  • Price$531
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 28905 Ponatinib-d8 1mg $354 2024-03-01 Buy
TRC P688252 Ponatinib-d8 1mg $220 2021-12-16 Buy
Usbiological 462817 Ponatinib-d8 1mg $531 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: soluble; Methanol: soluble
form :A solid
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Ponatinib-d8 is an isotope labelled compound of Ponatinib (P688250). Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. It is a COVID19-related research product.

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