Prostratin, PKC activator
- $68 - $2332.4
- Product name: Prostratin, PKC activator
- CAS: 60857-08-1
- MF: C22H30O6
- MW: 390.47
- EINECS:
- MDL Number:MFCD00674138
- Synonyms:SA 101A;Prostatin >99%;12-Deoxyphorbol 13-Acetate, dPAc;(1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-;13-O-Acetyl-12-deoxyphorbol;PROSTRATIN;(1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl- 5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one;13-O-Acetylphorbol
16 prices
Selected condition:
Brand
- Alfa Aesar
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1
- 500μg
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerAlfa Aesar
- Product numberJ60971
- Product descriptionProstratin, 99+%
- Packaging1mg
- Price$163
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60971
- Product descriptionProstratin, 99+%
- Packaging5mg
- Price$626
- Updated2023-06-20
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0006386
- Product description12-DEOXYPHORBOL 13-ACETATE 95.00%
- Packaging5MG
- Price$917.54
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0006386
- Product description12-DEOXYPHORBOL 13-ACETATE 95.00%
- Packaging1MG
- Price$672.09
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61078
- Product descriptionProstratin >99% pure
- Packaging1mg
- Price$389.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61078
- Product descriptionProstratin >99% pure
- Packaging5mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61078
- Product descriptionProstratin >99% pure
- Packaging10mg
- Price$1140.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61078
- Product descriptionProstratin >99% pure
- Packaging25mg
- Price$2332.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10272
- Product descriptionProstratin ≥98%
- Packaging500μg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10272
- Product descriptionProstratin ≥98%
- Packaging1mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10272
- Product descriptionProstratin
- Packaging5mg
- Price$435
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10272
- Product descriptionProstratin
- Packaging10mg
- Price$801
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0077
- Product descriptionProstratin ≥98% (HPLC)
- Packaging1mg
- Price$127
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberP0077
- Product descriptionProstratin ≥98% (HPLC)
- Packaging5mg
- Price$308.4
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5739
- Product descriptionProstratin ≥98%(HPLC)
- Packaging1
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP838800
- Product descriptionProstratin
- Packaging5mg
- Price$715
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Alfa Aesar | J60971 | Prostratin, 99+% | 1mg | $163 | 2023-06-20 | Buy |
Alfa Aesar | J60971 | Prostratin, 99+% | 5mg | $626 | 2023-06-20 | Buy |
American Custom Chemicals Corporation | CHM0006386 | 12-DEOXYPHORBOL 13-ACETATE 95.00% | 5MG | $917.54 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0006386 | 12-DEOXYPHORBOL 13-ACETATE 95.00% | 1MG | $672.09 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61078 | Prostratin >99% pure | 1mg | $389.3 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61078 | Prostratin >99% pure | 5mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61078 | Prostratin >99% pure | 10mg | $1140.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb61078 | Prostratin >99% pure | 25mg | $2332.4 | 2021-12-16 | Buy |
Cayman Chemical | 10272 | Prostratin ≥98% | 500μg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 10272 | Prostratin ≥98% | 1mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 10272 | Prostratin | 5mg | $435 | 2024-03-01 | Buy |
Cayman Chemical | 10272 | Prostratin | 10mg | $801 | 2024-03-01 | Buy |
Sigma-Aldrich | P0077 | Prostratin ≥98% (HPLC) | 1mg | $127 | 2024-03-01 | Buy |
Sigma-Aldrich | P0077 | Prostratin ≥98% (HPLC) | 5mg | $308.4 | 2024-03-01 | Buy |
Tocris | 5739 | Prostratin ≥98%(HPLC) | 1 | $113 | 2021-12-16 | Buy |
TRC | P838800 | Prostratin | 5mg | $715 | 2021-12-16 | Buy |
Properties
Melting point :216-219℃
Boiling point :550.5±50.0 °C(Predicted)
Density :1.31
storage temp. :-20°C
solubility :Soluble in DMSO at 30mg/ml
form :white powder
pka :11.40±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Boiling point :550.5±50.0 °C(Predicted)
Density :1.31
storage temp. :-20°C
solubility :Soluble in DMSO at 30mg/ml
form :white powder
pka :11.40±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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Description
Activation of latent reservoirs of HIV-infected cells is a treatment strategy designed to reduce viral load and eliminate the perpetuation of retroviral infection. Prostratin is a non-tumor promoting phorbol ester that potently induces HIV-1 reactivation in latent reservoirs of infected Jurkat-LAT-GFP cells with an IC50 value of ~0.5 μM. Originally, prostratin was isolated from plant sources including P. prostrata, E. cornigera, and H. nutans. The effects of prostratin are mediated through activation of NF-κB via protein kinase C and by downregulation of HIV-1 receptor CD4 expression and its co-receptors CXCR4 and CCR5.Related product price
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