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ChemicalBook >> CAS DataBase List >> Prostratin, PKC activator

Prostratin, PKC activator

Prostratin, PKC activator price.
  • $68 - $2332.4
  • Product name: Prostratin, PKC activator
  • CAS: 60857-08-1
  • MF: C22H30O6
  • MW: 390.47
  • EINECS:
  • MDL Number:MFCD00674138
  • Synonyms:SA 101A;Prostatin >99%;12-Deoxyphorbol 13-Acetate, dPAc;(1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-;13-O-Acetyl-12-deoxyphorbol;PROSTRATIN;(1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl- 5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one;13-O-Acetylphorbol
16 prices
Selected condition:
Brand
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAlfa Aesar
  • Product numberJ60971
  • Product descriptionProstratin, 99+%
  • Packaging1mg
  • Price$163
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60971
  • Product descriptionProstratin, 99+%
  • Packaging5mg
  • Price$626
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0006386
  • Product description12-DEOXYPHORBOL 13-ACETATE 95.00%
  • Packaging5MG
  • Price$917.54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0006386
  • Product description12-DEOXYPHORBOL 13-ACETATE 95.00%
  • Packaging1MG
  • Price$672.09
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61078
  • Product descriptionProstratin >99% pure
  • Packaging1mg
  • Price$389.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61078
  • Product descriptionProstratin >99% pure
  • Packaging5mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61078
  • Product descriptionProstratin >99% pure
  • Packaging10mg
  • Price$1140.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb61078
  • Product descriptionProstratin >99% pure
  • Packaging25mg
  • Price$2332.4
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10272
  • Product descriptionProstratin ≥98%
  • Packaging500μg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10272
  • Product descriptionProstratin ≥98%
  • Packaging1mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10272
  • Product descriptionProstratin
  • Packaging5mg
  • Price$435
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10272
  • Product descriptionProstratin
  • Packaging10mg
  • Price$801
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0077
  • Product descriptionProstratin ≥98% (HPLC)
  • Packaging1mg
  • Price$127
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0077
  • Product descriptionProstratin ≥98% (HPLC)
  • Packaging5mg
  • Price$308.4
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number5739
  • Product descriptionProstratin ≥98%(HPLC)
  • Packaging1
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP838800
  • Product descriptionProstratin
  • Packaging5mg
  • Price$715
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J60971 Prostratin, 99+% 1mg $163 2023-06-20 Buy
Alfa Aesar J60971 Prostratin, 99+% 5mg $626 2023-06-20 Buy
American Custom Chemicals Corporation CHM0006386 12-DEOXYPHORBOL 13-ACETATE 95.00% 5MG $917.54 2021-12-16 Buy
American Custom Chemicals Corporation CHM0006386 12-DEOXYPHORBOL 13-ACETATE 95.00% 1MG $672.09 2021-12-16 Buy
Biorbyt Ltd orb61078 Prostratin >99% pure 1mg $389.3 2021-12-16 Buy
Biorbyt Ltd orb61078 Prostratin >99% pure 5mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb61078 Prostratin >99% pure 10mg $1140.7 2021-12-16 Buy
Biorbyt Ltd orb61078 Prostratin >99% pure 25mg $2332.4 2021-12-16 Buy
Cayman Chemical 10272 Prostratin ≥98% 500μg $68 2024-03-01 Buy
Cayman Chemical 10272 Prostratin ≥98% 1mg $109 2024-03-01 Buy
Cayman Chemical 10272 Prostratin 5mg $435 2024-03-01 Buy
Cayman Chemical 10272 Prostratin 10mg $801 2024-03-01 Buy
Sigma-Aldrich P0077 Prostratin ≥98% (HPLC) 1mg $127 2024-03-01 Buy
Sigma-Aldrich P0077 Prostratin ≥98% (HPLC) 5mg $308.4 2024-03-01 Buy
Tocris 5739 Prostratin ≥98%(HPLC) 1 $113 2021-12-16 Buy
TRC P838800 Prostratin 5mg $715 2021-12-16 Buy

Properties

Melting point :216-219℃
Boiling point :550.5±50.0 °C(Predicted)
Density :1.31
storage temp. :-20°C
solubility :Soluble in DMSO at 30mg/ml
form :white powder
pka :11.40±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Activation of latent reservoirs of HIV-infected cells is a treatment strategy designed to reduce viral load and eliminate the perpetuation of retroviral infection. Prostratin is a non-tumor promoting phorbol ester that potently induces HIV-1 reactivation in latent reservoirs of infected Jurkat-LAT-GFP cells with an IC50 value of ~0.5 μM. Originally, prostratin was isolated from plant sources including P. prostrata, E. cornigera, and H. nutans. The effects of prostratin are mediated through activation of NF-κB via protein kinase C and by downregulation of HIV-1 receptor CD4 expression and its co-receptors CXCR4 and CCR5.

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