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ChemicalBook >> CAS DataBase List >> Pyrintegrin

Pyrintegrin

Pyrintegrin price.
  • $84 - $850
  • Product name: Pyrintegrin
  • CAS: 1228445-38-2
  • MF: C23H25N5O3S
  • MW: 451.54
  • EINECS:
  • MDL Number:MFCD25976569
  • Synonyms:Pyrintegrin;N-(Cyclopropylmethyl)-4-{[4-(6-hydroxy-3,4-dihydro-1(2H)-quinolinyl)-2-pyrimidinyl]amino}benzenesulfonamide;N-(Cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]benzenesulfonamide;Benzenesulfonamide, N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-;nephropathy,C/EBPα,embryonic,stem,inhibit,β1-integrin,PPARγ,Integrin,Pyrintegrin,Adipogenic,cells,Inhibitor,podocyte-protective,ECM,proteinuria
14 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number3608DG
  • Product descriptionPyrintegrin
  • Packaging10mg
  • Price$461
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3882
  • Product descriptionPyrintegrin
  • Packaging5mg
  • Price$255
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16179
  • Product descriptionPyrintegrin ≥95%
  • Packaging1mg
  • Price$84
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16179
  • Product descriptionPyrintegrin ≥95%
  • Packaging5mg
  • Price$225
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16179
  • Product descriptionPyrintegrin ≥95%
  • Packaging10mg
  • Price$328
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003191
  • Product descriptionPyrintegrin 97.04%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003191
  • Product descriptionPyrintegrin 97.04%
  • Packaging10mg
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003191
  • Product descriptionPyrintegrin 97.04%
  • Packaging50mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number48478
  • Product descriptionPyrintegrin
  • Packaging2.5mg
  • Price$625
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4978
  • Product descriptionPyrintegrin ≥98%(HPLC)
  • Packaging10
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberP994705
  • Product descriptionPyrintegrin
  • Packaging2.5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberP9523
  • Product descriptionPyrintegrin
  • Packaging1mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number366909
  • Product descriptionPyrintegrin
  • Packaging10mg
  • Price$485
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256373
  • Product descriptionPyrintegrin
  • Packaging10mg
  • Price$644
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3608DG Pyrintegrin 10mg $461 2021-12-16 Buy
ApexBio Technology C3882 Pyrintegrin 5mg $255 2021-12-16 Buy
Cayman Chemical 16179 Pyrintegrin ≥95% 1mg $84 2024-03-01 Buy
Cayman Chemical 16179 Pyrintegrin ≥95% 5mg $225 2024-03-01 Buy
Cayman Chemical 16179 Pyrintegrin ≥95% 10mg $328 2024-03-01 Buy
ChemScene CS-0003191 Pyrintegrin 97.04% 5mg $180 2021-12-16 Buy
ChemScene CS-0003191 Pyrintegrin 97.04% 10mg $265 2021-12-16 Buy
ChemScene CS-0003191 Pyrintegrin 97.04% 50mg $850 2021-12-16 Buy
Medical Isotopes, Inc. 48478 Pyrintegrin 2.5mg $625 2021-12-16 Buy
Tocris 4978 Pyrintegrin ≥98%(HPLC) 10 $360 2021-12-16 Buy
TRC P994705 Pyrintegrin 2.5mg $130 2021-12-16 Buy
Usbiological P9523 Pyrintegrin 1mg $350 2021-12-16 Buy
Usbiological 366909 Pyrintegrin 10mg $485 2021-12-16 Buy
Usbiological 256373 Pyrintegrin 10mg $644 2021-12-16 Buy

Properties

Boiling point :729.3±70.0 °C(Predicted)
Density :1.401±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤1mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
form :crystalline solid
pka :9.75±0.20(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Human embryonic stem cells (hESC), unlike murine ESC, grow in vitro as large flattened two dimensional colonies. Dispersing these colonies, using trypsin to dissociate single hESC, results in massive cell death. Pyrintegrin is a 2,4-disubstituted pyrimidine that, at 2 μM, enhances the survival of hESC more than 30-fold after trypsin-mediated dissociation. It increases integrin-dependent attachment of hESC to extracellular matrices, including Matrigel? and laminin, without significantly impacting cell proliferation. Pyrintegrin increases the binding of the activated β1 integrin-specific antibody HUTS-21 and enhances the phosphorylation of multiple growth factor receptors and their downstream kinases, PI3K and MAPK.