(R)-MG132
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- $44 - $980
- Product name: (R)-MG132
- CAS: 1211877-36-9
- MF: C26H41N3O5
- MW: 475.62
- EINECS:
- MDL Number:MFCD28580122
- Synonyms:(R)-MG132;Cbz-L-leu-D-leu-L-leu-H;N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide;MG-132(R);benzyl N-[(2S)-4-methyl-1-[[(2R)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate;MG-132(S,R,S);(S,R,S)-(-)-MG-132;Z-Leu-D-leu-leu-al
14 prices
Selected condition：
Brand
- ACHEMBLOCK
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
Package
- 2.5mg
- 10
- 1mg
- 5MG
- 10mg
- 25MG
- 50mg
- 100MG
- ManufacturerACHEMBLOCK
- Product numberL21895
- Product description(R)-MG132 98%
- Packaging5MG
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21895
- Product description(R)-MG132 98%
- Packaging25MG
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberL21895
- Product description(R)-MG132 98%
- Packaging100MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13697
- Product description(R)-MG132 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13697
- Product description(R)-MG132 ≥98%
- Packaging5mg
- Price$202
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13697
- Product description(R)-MG132 ≥98%
- Packaging10mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13697
- Product description(R)-MG132 ≥98%
- Packaging25mg
- Price$796
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0021842
- Product description(R)-MG-132 ≥98.0%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0021842
- Product description(R)-MG-132 ≥98.0%
- Packaging10mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0021842
- Product description(R)-MG-132 ≥98.0%
- Packaging50mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberM8699
- Product description(R)-MG132
- Packaging1MG
- Price$180
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1135
- Product descriptionMG-132(R) ≥95% (HPLC)
- Packaging5mg
- Price$482
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number6033
- Product description(R)-MG132 ≥98%(HPLC)
- Packaging10
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberM340975
- Product description(R)-MG-132
- Packaging2.5mg
- Price$85
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | L21895 | (R)-MG132 98% | 5MG | $80 | 2021-12-16 | Buy |
| ACHEMBLOCK | L21895 | (R)-MG132 98% | 25MG | $195 | 2021-12-16 | Buy |
| ACHEMBLOCK | L21895 | (R)-MG132 98% | 100MG | $450 | 2021-12-16 | Buy |
| Cayman Chemical | 13697 | (R)-MG132 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 13697 | (R)-MG132 ≥98% | 5mg | $202 | 2024-03-01 | Buy |
| Cayman Chemical | 13697 | (R)-MG132 ≥98% | 10mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 13697 | (R)-MG132 ≥98% | 25mg | $796 | 2024-03-01 | Buy |
| ChemScene | CS-0021842 | (R)-MG-132 ≥98.0% | 5mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-0021842 | (R)-MG-132 ≥98.0% | 10mg | $320 | 2021-12-16 | Buy |
| ChemScene | CS-0021842 | (R)-MG-132 ≥98.0% | 50mg | $980 | 2021-12-16 | Buy |
| Sigma-Aldrich | M8699 | (R)-MG132 | 1MG | $180 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1135 | MG-132(R) ≥95% (HPLC) | 5mg | $482 | 2024-03-01 | Buy |
| Tocris | 6033 | (R)-MG132 ≥98%(HPLC) | 10 | $310 | 2021-12-16 | Buy |
| TRC | M340975 | (R)-MG-132 | 2.5mg | $85 | 2021-12-16 | Buy |
Properties
Boiling point :682.0±55.0 °C(Predicted)
Density :1.073±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml
pka :11.14±0.46(Predicted)
form :powder
color :White to off-white
Density :1.073±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 25 mg/ml
pka :11.14±0.46(Predicted)
form :powder
color :White to off-white
Safety Information
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Description
The ubiquitin-proteasome pathway plays an integral role in the selective degradation of intracellular proteins. While important for clearing damaged or mis-folded proteins, this proteolytic pathway also regulates the availability of key proteins involved in the control of inflammatory processes, cell cycle regulation, and gene expression. (R)-MG132 is a potent, reversible, and cell permeable proteasome inhibitor. After treatment for one hour at 100 nM, it inhibits 50% and 31% of proteasome activity in lysates of J558L multiple myeloma cells and EMT6 breast cancer cells, respectively. The (R)-MG132 stereoisomer is a more effective inhibitor of chymotrypsin-like (ChTL), trypsin-like (TL), and peptidylglutamyl peptide hydrolyzing proteasome (PGPH) activities compared to (S)-MG132 (IC50s = 0.22 versus 0.89 μM (ChTL); 34.4 versus 104.43 μM (TL); 2.95 versus 5.70 μM (PGPH), respectively).Related product price
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