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ChemicalBook >> CAS DataBase List >> RG-7388

RG-7388

RG-7388 price.
  • $47 - $2200
  • Product name: RG-7388
  • CAS: 1229705-06-9
  • MF: C31H29Cl2F2N3O4
  • MW: 616.48
  • EINECS:
  • MDL Number:MFCD26142931
  • Synonyms:4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid;RG 7388;RG-7388;RG-7388, Idasanutlin;Idasanutlin (RG-7388);4-[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimet;RG 7388; RG-7388; RG7388;4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid
Price25 Properties Safety Information Description
25 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • BroadPharm
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 50
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5690
  • Product descriptionRG7388
  • Packaging1mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3763
  • Product descriptionRG7388
  • Packaging10mM(in 1mL DMSO)
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR104258
  • Product descriptionRG 7388
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR104258
  • Product descriptionRG 7388
  • Packaging2mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR104258
  • Product descriptionRG 7388
  • Packaging5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR104258
  • Product descriptionRG 7388
  • Packaging10mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR104258
  • Product descriptionRG 7388
  • Packaging25mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-25380
  • Product descriptionIdasanutlin
  • Packaging25mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21532
  • Product descriptionRG7388 ≥98%
  • Packaging1mg
  • Price$47
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21532
  • Product descriptionRG7388 ≥98%
  • Packaging5mg
  • Price$206
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21532
  • Product descriptionRG7388 ≥98%
  • Packaging10mg
  • Price$339
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21532
  • Product descriptionRG7388 ≥98%
  • Packaging25mg
  • Price$564
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM161396
  • Product description4-[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoicacid 98%
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1473
  • Product descriptionIdasanutlin 99.90%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1473
  • Product descriptionIdasanutlin 99.90%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1473
  • Product descriptionIdasanutlin 99.90%
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5690 RG7388 1mg $76 2021-12-16 Buy
ApexBio Technology A3763 RG7388 10mM(in 1mL DMSO) $150 2021-12-16 Buy
Biosynth Carbosynth FR104258 RG 7388 1mg $100 2021-12-16 Buy
Biosynth Carbosynth FR104258 RG 7388 2mg $150 2021-12-16 Buy
Biosynth Carbosynth FR104258 RG 7388 5mg $250 2021-12-16 Buy
Biosynth Carbosynth FR104258 RG 7388 10mg $350 2021-12-16 Buy
Biosynth Carbosynth FR104258 RG 7388 25mg $500 2021-12-16 Buy
BroadPharm BP-25380 Idasanutlin 25mg $320 2021-12-16 Buy
Cayman Chemical 21532 RG7388 ≥98% 1mg $47 2024-03-01 Buy
Cayman Chemical 21532 RG7388 ≥98% 5mg $206 2024-03-01 Buy
Cayman Chemical 21532 RG7388 ≥98% 10mg $339 2024-03-01 Buy
Cayman Chemical 21532 RG7388 ≥98% 25mg $564 2024-03-01 Buy
Chemenu CM161396 4-[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoicacid 98% 100mg $350 2021-12-16 Buy
ChemScene CS-1473 Idasanutlin 99.90% 5mg $70 2021-12-16 Buy
ChemScene CS-1473 Idasanutlin 99.90% 10mg $120 2021-12-16 Buy
ChemScene CS-1473 Idasanutlin 99.90% 50mg $290 2021-12-16 Buy
Next Last

Properties

Melting point :>261° (dec.)
Boiling point :737.3±60.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :4.11±0.10(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Potent MDM2 inhibitor with an IC50 = 6 nM in binding assay and 30 nM in cancer cell proliferation assay. Induces p53 stabilisation, cell cycle arrest and apoptosis in cancer cells expression wildtype p53. Displays inhibition of tumor growth in the SJSA1 tumor xenograft model. Also inhibits MDR-1 at high concentrations.

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Suppliers and manufacturers

career henan chemical co
RG-7388
$2.00 /1KG
RG-7388 CAS:1229705-06-9
ATK CHEMICAL COMPANY LIMITED
Hangzhou FandaChem Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
Biochempartner
BOC Sciences
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Chemia Biotechnology（Shanghai） Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited