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ChemicalBook >> RIZ1 (human recombinant)

RIZ1 (human recombinant)

RIZ1 (human recombinant) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 250μg
  • ManufacturerCayman Chemical
  • Product number10765
  • Product descriptionRIZ1 (human recombinant)
  • Packaging250μg
  • Price$359
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10765 RIZ1 (human recombinant) 250μg $359 2024-03-01 Buy

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Description

Retinoblastoma protein-interacting zinc finger protein 1 (RIZ1), also known as PRDM2, is a SAM-dependent histone methyltransferase that specifically methylates histone H3 on lysine 9. RIZ1 contains 8 zinc-finger motifs and 1 PR domain. The RIZ gene encodes two different proteins, RIZ1 and RIZ2. RIZ1 is a tumor suppressor that can arrest the cell cycle and induce apoptosis. RIZ2 however, is a proto-oncoprotein lacking the N-terminal PR domain containing the methyltransferase activity. When RIZ1 is silenced or mutated, the reduced methyltransferase activity can lead to inheritable changes in chromatin methylation and gene expression patterns.

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