RO 25-6981 HYDROCHLORIDE

$179 - $613
Product name: RO 25-6981 HYDROCHLORIDE
CAS: 919289-58-0
MF: C22H30ClNO2
MW: 375.93
EINECS:
MDL Number:MFCD02684414
Synonyms:[R-(R*,S*)]-ALPHA-(4-HYDROXYPHENYL)-BETA-METHYL-4-(PHENYLMETHYL)-1-PIPERIDINEPROPANOL HYDROCHLORIDE;[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride;[R-(R*,S*)]-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol hydrochloride hydrate;Ro 25-6981 hydrochloride hydrate;Ro 25-6981 HCl;Ro 256981 HCl;Ro 25 6981 HCl;4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol

Price2 Properties Safety Information Description

2 prices

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Brand

Package

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Sigma-Aldrich	R7150	Ro 25-6981 hydrochloride hydrate ≥98% (HPLC), powder	5MG	$179	2024-03-01	Buy
Sigma-Aldrich	R7150	Ro 25-6981 hydrochloride hydrate ≥98% (HPLC), powder	25MG	$613	2024-03-01	Buy

Properties

solubility :H₂O: 2 mg/mL
form :powder
color :white

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Ro 25-6981 hydrochloride hydrate has been used:

as NR2B antagonist for microinjecting rats to study the contribution of NR2B- and NR2A-containing N-methyl-D-aspartate receptors (NMDARs) to the formation of trace and contextual memory in prefrontal cortex (PL)
as NR2B antagonist to study the effect of the protein expression of hypoxic-ischemic injury NMDAR subunits 2A and 2B in the SVZ of neonatal rats
to induce deleterious effects upon memory consolidation and long-term potentiation (LTP) generation in the hippocampus

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