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ChemicalBook >> CAS DataBase List >> RO 48-8071

RO 48-8071

RO 48-8071 price.
  • $44 - $1500
  • Product name: RO 48-8071
  • CAS: 189197-69-1
  • MF: C23H27BrFNO2.C4H4O4
  • MW: 564.45
  • EINECS:
  • MDL Number:MFCD05865242
  • Synonyms:Ro 48-8071 fumarate salt;(4-((6-(allyl(methyl)amino)hexyl)oxy)-2-fluorophenyl)(4-bromophenyl)methanone fumarate Ro48-8071;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone (2E)-2-butenedioate (1:1);OSC Inhibitor, Ro 48-8071 ;Aids163155;Aids-163155;Methanone, (4-bromophenyl)[2-fluoro-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl]-,(2E)-2-butenedioate;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
22 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4012AH
  • Product description(4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid
  • Packaging5mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4012AH
  • Product description(4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid
  • Packaging100mg
  • Price$628
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67231
  • Product descriptionRo 48-8071, 98%
  • Packaging10mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA674342
  • Product descriptionRo48-8071fumarate 98+%
  • Packaging5mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA674342
  • Product descriptionRo48-8071fumarate 98+%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA674342
  • Product descriptionRo48-8071fumarate 98+%
  • Packaging25mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA674342
  • Product descriptionRo48-8071fumarate 98+%
  • Packaging50mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000522
  • Product descriptionRO 48-8071 FUMARATE 95.00%
  • Packaging5MG
  • Price$761.66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000522
  • Product descriptionRO 48-8071 FUMARATE 95.00%
  • Packaging25MG
  • Price$1270.96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4860
  • Product descriptionRo48-8071fumarate
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4860
  • Product descriptionRo48-8071fumarate
  • Packaging10mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4860
  • Product descriptionRo48-8071fumarate
  • Packaging50mg
  • Price$236
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4860
  • Product descriptionRo48-8071fumarate
  • Packaging100mg
  • Price$394
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR103645
  • Product descriptionRo 48-8071 fumarate
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFR103645
  • Product descriptionRo 48-8071 fumarate
  • Packaging50mg
  • Price$262.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002850
  • Product descriptionRo48-8071fumarate 98+%
  • Packaging50mg
  • Price$248
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4012AH (4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid 5mg $113 2021-12-16 Buy
AK Scientific 4012AH (4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid 100mg $628 2021-12-16 Buy
Alfa Aesar J67231 Ro 48-8071, 98% 10mg $116 2021-12-16 Buy
Ambeed A674342 Ro48-8071fumarate 98+% 5mg $44 2021-12-16 Buy
Ambeed A674342 Ro48-8071fumarate 98+% 10mg $65 2021-12-16 Buy
Ambeed A674342 Ro48-8071fumarate 98+% 25mg $85 2021-12-16 Buy
Ambeed A674342 Ro48-8071fumarate 98+% 50mg $111 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000522 RO 48-8071 FUMARATE 95.00% 5MG $761.66 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000522 RO 48-8071 FUMARATE 95.00% 25MG $1270.96 2021-12-16 Buy
ApexBio Technology B4860 Ro48-8071fumarate 5mg $70 2021-12-16 Buy
ApexBio Technology B4860 Ro48-8071fumarate 10mg $124 2021-12-16 Buy
ApexBio Technology B4860 Ro48-8071fumarate 50mg $236 2021-12-16 Buy
ApexBio Technology B4860 Ro48-8071fumarate 100mg $394 2021-12-16 Buy
Biosynth Carbosynth FR103645 Ro 48-8071 fumarate 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FR103645 Ro 48-8071 fumarate 50mg $262.5 2021-12-16 Buy
Crysdot CD31002850 Ro48-8071fumarate 98+% 50mg $248 2021-12-16 Buy

Properties

Melting point :90-92.7 °C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ro 48-8071 fumarate is an orally active 2,3-oxidosqualene lanosterol cyclase (OSC) inhibitor where OSC represents a unique target for a cholesterol-lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG-CoA reductase expression, generating a synergistic, self-limited negative regulatory loop.

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