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ChemicalBook >> CAS DataBase List >> RU-505

RU-505

RU-505 price.
  • $57 - $2225
  • Product name: RU-505
  • CAS: 1314206-29-5
  • MF: C28H32FN5O
  • MW: 473.58
  • EINECS:
  • MDL Number:MFCD19941010
  • Synonyms:RU-505;Pyrazolo[1,5-a]pyrimidine-5-carboxamide, N-[2-(dimethylamino)ethyl]-2-(1,1-dimethylethyl)-7-(4-fluorophenyl)-N-(phenylmethyl)-
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 100mg
  • ManufacturerAK Scientific
  • Product numberSYN5027
  • Product descriptionRU-505
  • Packaging100mg
  • Price$2225
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16445
  • Product descriptionRU-505 ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16445
  • Product descriptionRU-505 ≥98%
  • Packaging5mg
  • Price$249
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16445
  • Product descriptionRU-505 ≥98%
  • Packaging10mg
  • Price$437
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5027 RU-505 100mg $2225 2021-12-16 Buy
Cayman Chemical 16445 RU-505 ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 16445 RU-505 ≥98% 5mg $249 2024-03-01 Buy
Cayman Chemical 16445 RU-505 ≥98% 10mg $437 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

RU-505 is an inhibitor of the interaction between amyloid-β (Aβ) and fibrinogen, with a higher efficacy for inhibiting monomeric forms of Aβ bound to fibrinogen over oligomeric forms. In vitro, RU-505 (20 μM) normalizes fibrin clot formation that is disrupted when fibrinogen is bound to Aβ42. RU-505 (35 mg/kg) decreases the incidence of vessel occlusion in the Tg6799 transgenic mouse model of Alzheimer’s disease. Chronic treatment with RU-505 (35 mg/kg, s.c., every other day for 3 months) decreases Aβ deposition in blood vessels and cortical fibrinogen infiltration and microgliosis in the brain of Tg6799 mice. In addition, it improves spatial memory in chronically treated Tg6799 mice compared with vehicle control mice.

Suppliers and manufacturers

TargetMol Chemicals Inc.
RU-505
$143.00 /1mg
RU-505 CAS:1314206-29-5
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Amadis Chemical Company Limited Pharmacodia (Beijing) Co.,Ltd Shanghai EFE Biological Technology Co., Ltd. Lynnchem Novachemistry Changzhou Furuisi Biotechnology Co., Ltd TargetMol Chemicals Inc. Nanjing Tengyi Biotechnology Co., Ltd