ReModelin
|
- $49 - $693
- Product name: ReModelin
- CAS: 949912-58-7
- MF: C15H14N4S
- MW: 282.36
- EINECS:
- MDL Number:MFCD28167837
- Synonyms:ReModelin;4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile hydrobromide;4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]benzonitrile;CS-2149;Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-;Reaxys ID: 18559527;4-(2-(2-Cyclopentylidenehydrazineyl)thiazol-4-yl)benzonitrile;4- (2- (2-cyclopentylidenehydrazine) thiazol-4-yl) benzonitrile
17 prices
Selected condition：
Brand
- AK Scientific
- Axon Medchem
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50
- 5mg
- 1mg
- 10
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product numberSYN5222
- Product descriptionRemodelin
- Packaging10mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2299
- Product descriptionRemodelin 99%
- Packaging2x5mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17346
- Product descriptionRemodelin ≥95%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17346
- Product descriptionRemodelin ≥95%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17346
- Product descriptionRemodelin ≥95%
- Packaging10mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17346
- Product descriptionRemodelin ≥95%
- Packaging25mg
- Price$416
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM161289
- Product description4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrile 98%
- Packaging50mg
- Price$373
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000109
- Product descriptionRemodelin 98+%
- Packaging50mg
- Price$395
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000109
- Product descriptionRemodelin 98+%
- Packaging10mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000109
- Product descriptionRemodelin 98+%
- Packaging5mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8646
- Product descriptionRemodelin >98%
- Packaging100mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1112
- Product descriptionRemodelin hydrobromide ≥98% (HPLC)
- Packaging5mg
- Price$138
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1112
- Product descriptionRemodelin hydrobromide ≥98% (HPLC)
- Packaging25mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number5.31066
- Product descriptionRemodelin
- Packaging25MG
- Price$260
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5193
- Product descriptionRemodelin ≥99%(HPLC)
- Packaging10
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5193
- Product descriptionRemodelin ≥99%(HPLC)
- Packaging50
- Price$693
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5222 | Remodelin | 10mg | $165 | 2021-12-16 | Buy |
| Axon Medchem | Axon2299 | Remodelin 99% | 2x5mg | $154 | 2021-12-16 | Buy |
| Cayman Chemical | 17346 | Remodelin ≥95% | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 17346 | Remodelin ≥95% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 17346 | Remodelin ≥95% | 10mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 17346 | Remodelin ≥95% | 25mg | $416 | 2024-03-01 | Buy |
| Chemenu | CM161289 | 4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrile 98% | 50mg | $373 | 2021-12-16 | Buy |
| Crysdot | CD31000109 | Remodelin 98+% | 50mg | $395 | 2021-12-16 | Buy |
| Crysdot | CD31000109 | Remodelin 98+% | 10mg | $94 | 2021-12-16 | Buy |
| Crysdot | CD31000109 | Remodelin 98+% | 5mg | $52 | 2021-12-16 | Buy |
| DC Chemicals | DC8646 | Remodelin >98% | 100mg | $400 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1112 | Remodelin hydrobromide ≥98% (HPLC) | 5mg | $138 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1112 | Remodelin hydrobromide ≥98% (HPLC) | 25mg | $214 | 2024-03-01 | Buy |
| Sigma-Aldrich | 5.31066 | Remodelin | 25MG | $260 | 2024-03-01 | Buy |
| Tocris | 5193 | Remodelin ≥99%(HPLC) | 10 | $168 | 2021-12-16 | Buy |
| Tocris | 5193 | Remodelin ≥99%(HPLC) | 50 | $693 | 2021-12-16 | Buy |
Properties
Boiling point :498.9±47.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :14.40±0.20(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :14.40±0.20(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 μM, improves nuclear architecture, chromatin organization, and survival of both cells lacking lamin A and cells from patients with progeria. Remodelin is an inhibitor of N-acetyltransferase 10 (NAT10), which acetylates both histones and microtubules. Mutation of NAT10 mimics the effects of remodelin on nuclear morphology, suggesting that these effects of remodelin require NAT10. Remodelin also has cytotoxic effects against some species of the fungus Candida.Related product price
- ReModelin hydrobroMide
$37-1125 - ACP196
$32-1744 - Fruquintinib|HMPL-013
$50-849
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