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ChemicalBook >> CAS DataBase List >> Ro 67-4853

Ro 67-4853

Ro 67-4853 price.
  • $32 - $2200
  • Product name: Ro 67-4853
  • CAS: 302841-89-0
  • MF: C19H19NO4
  • MW: 325.36
  • EINECS:
  • MDL Number:MFCD20270618
  • Synonyms:Ro 67-4853;(9H-Xanthen-9-ylcarbonyl)carbaMic Acid Butyl Ester;N-(9H-Xanthen-9-ylcarbonyl)carbaMic Acid Butyl Ester;Butyl 9H-xanthene-9-carbonylcarbamate;Carbamic acid, N-(9H-xanthen-9-ylcarbonyl)-, butyl ester;Ro 674853,Ro 67 4853
Price15 Properties Safety Information Description
15 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10mg
  • 25MG
  • 50mg
  • 250MG
  • ManufacturerAK Scientific
  • Product number4451CR
  • Product descriptionButyl9H-xanthene-9-carbonylcarbamate
  • Packaging5mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010310
  • Product description(9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00%
  • Packaging25MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010310
  • Product description(9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00%
  • Packaging250MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7653
  • Product descriptionRo67-4853
  • Packaging10mg
  • Price$219
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7653
  • Product descriptionRo67-4853
  • Packaging50mg
  • Price$921
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11992
  • Product descriptionRo 67-4853 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11992
  • Product descriptionRo 67-4853 ≥98%
  • Packaging5mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11992
  • Product descriptionRo 67-4853 ≥98%
  • Packaging10mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number48600
  • Product descriptionRo67-4853
  • Packaging250mg
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1190
  • Product descriptionRo 67-4853 ≥98% (HPLC)
  • Packaging5MG
  • Price$102
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1190
  • Product descriptionRo 67-4853 ≥98% (HPLC)
  • Packaging25MG
  • Price$398
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number4347
  • Product descriptionRo67-4853 ≥99%(HPLC)
  • Packaging10
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4347
  • Product descriptionRo67-4853 ≥99%(HPLC)
  • Packaging50
  • Price$597
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberR637400
  • Product descriptionRo67-4853
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256491
  • Product descriptionRo 67-4853
  • Packaging10mg
  • Price$389
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4451CR Butyl9H-xanthene-9-carbonylcarbamate 5mg $164 2021-12-16 Buy
American Custom Chemicals Corporation API0010310 (9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00% 25MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation API0010310 (9H-XANTHEN-9-YLCARBONYL)CARBAMIC ACID BUTYL ESTER 95.00% 250MG $1963.5 2021-12-16 Buy
ApexBio Technology B7653 Ro67-4853 10mg $219 2021-12-16 Buy
ApexBio Technology B7653 Ro67-4853 50mg $921 2021-12-16 Buy
Cayman Chemical 11992 Ro 67-4853 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 11992 Ro 67-4853 ≥98% 5mg $61 2024-03-01 Buy
Cayman Chemical 11992 Ro 67-4853 ≥98% 10mg $93 2024-03-01 Buy
Medical Isotopes, Inc. 48600 Ro67-4853 250mg $2200 2021-12-16 Buy
Sigma-Aldrich SML1190 Ro 67-4853 ≥98% (HPLC) 5MG $102 2022-05-15 Buy
Sigma-Aldrich SML1190 Ro 67-4853 ≥98% (HPLC) 25MG $398 2022-05-15 Buy
Tocris 4347 Ro67-4853 ≥99%(HPLC) 10 $142 2021-12-16 Buy
Tocris 4347 Ro67-4853 ≥99%(HPLC) 50 $597 2021-12-16 Buy
TRC R637400 Ro67-4853 10mg $70 2021-12-16 Buy
Usbiological 256491 Ro 67-4853 10mg $389 2021-12-16 Buy

Properties

Melting point :190-194°C
storage temp. :Refrigerator
solubility :Chloroform, Methanol
form :Solid
color :White

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8, as well as at several other neural receptors. Ro 67-4853 can also directly activate mGluR1 signaling in baby hamster kidney cells, leading to phosphorylation of ERK1/2 (EC50 = 6.2 nM) and activation of adenylate cyclase (EC50 = 11.7 μM). Ro 67-4853 can also be used to enhance neuronal stimulation in response to the mGluR1/mGluR5 agonist DHPG, both in vivo and in vitro (EC50 = 95 nM).

Suppliers and manufacturers

TargetMol Chemicals Inc.
Aladdin Scientific J & K SCIENTIFIC LTD. Chemsky（shanghai）International Co.,Ltd. EMMX Biotechnology LLC Shenzhen Polymeri Biochemical Technology Co., Ltd. BOC Sciences ShangHai ChuanQian Chemcial Technique Centre Energy Chemical MedBioPharmaceutical Technology Inc