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ChemicalBook >> CAS DataBase List >> Ro 67-7476

Ro 67-7476

Ro 67-7476 price.
  • $32 - $1575
  • Product name: Ro 67-7476
  • CAS: 298690-60-5
  • MF: C17H18FNO2S
  • MW: 319.39
  • EINECS:
  • MDL Number:MFCD20270617
  • Synonyms:Ro 67-7476;Pyrrolidine, 2-(4-fluorophenyl)-1-[(4-methylphenyl) sulfonyl]-, (2S)-;(2S)-2-(4-Fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine;RO67-7476;RO-67-7476;excitatory postsynaptic potentials,Ro 67-7476,cAMP accumulation,mGluR,neuronal culture,Metabotropic glutamate receptors,Ro 67 7476,inhibit,Ro 677476,traumatic injury,mGluR1,Inhibitor
26 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1MG
  • 2mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number5300DD
  • Product descriptionPyrrolidine,2-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-,(2S)-
  • Packaging10mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010269
  • Product description(2S)-2-(4-FLUOROPHENYL)-1-[(4-METHYLPHENYL)SULFONYL]PYRROLIDINE 95.00%
  • Packaging1MG
  • Price$714.32
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5560
  • Product descriptionRo67-7476
  • Packaging2mg
  • Price$79
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5560
  • Product descriptionRo67-7476
  • Packaging5mg
  • Price$158
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5560
  • Product descriptionRo67-7476
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5560
  • Product descriptionRo67-7476
  • Packaging25mg
  • Price$520
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5560
  • Product descriptionRo67-7476
  • Packaging50mg
  • Price$945
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5560
  • Product descriptionRo67-7476
  • Packaging100mg
  • Price$1575
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb611860
  • Product descriptionRo 67-7476 >98%
  • Packaging10mg
  • Price$345.1
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb611860
  • Product descriptionRo 67-7476 >98%
  • Packaging50mg
  • Price$805.8
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb611860
  • Product descriptionRo 67-7476 >98%
  • Packaging100mg
  • Price$1326
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number11993
  • Product descriptionRo 67-7476
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number11993
  • Product descriptionRo 67-7476
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number11993
  • Product descriptionRo 67-7476
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11993
  • Product descriptionRo 67-7476
  • Packaging25mg
  • Price$494
  • Updated2024-03-01
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  • ManufacturerChemScene
  • Product numberCS-5751
  • Product descriptionRo67-7476 99.80%
  • Packaging2mg
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5300DD Pyrrolidine,2-(4-fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-,(2S)- 10mg $336 2021-12-16 Buy
American Custom Chemicals Corporation API0010269 (2S)-2-(4-FLUOROPHENYL)-1-[(4-METHYLPHENYL)SULFONYL]PYRROLIDINE 95.00% 1MG $714.32 2021-12-16 Buy
ApexBio Technology B5560 Ro67-7476 2mg $79 2021-12-16 Buy
ApexBio Technology B5560 Ro67-7476 5mg $158 2021-12-16 Buy
ApexBio Technology B5560 Ro67-7476 10mg $252 2021-12-16 Buy
ApexBio Technology B5560 Ro67-7476 25mg $520 2021-12-16 Buy
ApexBio Technology B5560 Ro67-7476 50mg $945 2021-12-16 Buy
ApexBio Technology B5560 Ro67-7476 100mg $1575 2021-12-16 Buy
Biorbyt Ltd orb611860 Ro 67-7476 >98% 10mg $345.1 2021-12-16 Buy
Biorbyt Ltd orb611860 Ro 67-7476 >98% 50mg $805.8 2021-12-16 Buy
Biorbyt Ltd orb611860 Ro 67-7476 >98% 100mg $1326 2021-12-16 Buy
Cayman Chemical 11993 Ro 67-7476 1mg $32 2024-03-01 Buy
Cayman Chemical 11993 Ro 67-7476 5mg $139 2024-03-01 Buy
Cayman Chemical 11993 Ro 67-7476 10mg $214 2024-03-01 Buy
Cayman Chemical 11993 Ro 67-7476 25mg $494 2024-03-01 Buy
ChemScene CS-5751 Ro67-7476 99.80% 2mg $50 2021-12-16 Buy

Properties

Boiling point :452.9±55.0 °C(Predicted)
Density :1.268±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO:30.0(Max Conc. mg/mL);93.9(Max Conc. mM)
pka :-5.53±0.40(Predicted)
form :Powder
color :White to yellow

Safety Information

Symbol(GHS):
Signal word:
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Description

Ro 67-7476 is a positive allosteric modulator of metabotropic glutamate receptor 1 (mGluR1) that enhances glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a (EC50 = 1.74 μM). It is selective for rat mGluR1 over rat mGluR2, mGluR4, and mGluR8 at a concentration of 10 μM. Ro 67-7476 increases the amplitude of mGluR1 excitatory postsynaptic potentials (EPSCs) evoked by 2,3-dihydroxy-6-nitro-7-sulfamoylbenzoquionxaline, picrotoxin, or AP5 in the Purkinje cells of rat cerebellar slices. It activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50 = 163.3 nM).