Roxadustat
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- $32 - $6800
- Product name: Roxadustat
- CAS: 808118-40-3
- MF: C19H16N2O5
- MW: 352.34
- EINECS:813-400-2
- MDL Number:MFCD20040519
- Synonyms:FG-4592; 2-(4-HYDROXY-1-METHYL-7-PHENOXYISOQUINOLINE-3-CARBOXAMIDO)ACETIC ACID;[[(4-Hydroxy-1-Methyl-7-phenoxyisoquinolin-3-yl)carbonyl]aMino]acetic Acid;FG-4592/FG4592;Glycine, N-[(4-hydroxy-1-Methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-;FG-4592(ASP1517);FibroGen;2-[(4-hydroxy-1-Methyl-7-phenoxyisoquinoline-3-carbonyl)aMino]acetic acid;N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine [[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid
35 prices
Selected condition：
Brand
- Activate Scientific
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
Package
- 5mg
- 10MG
- 20mg
- 25mg
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 5g
- ManufacturerActivate Scientific
- Product numberAS112067
- Product descriptionRoxadustat (FG-4592) 96%
- Packaging25mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS112067
- Product descriptionRoxadustat (FG-4592) 96%
- Packaging100mg
- Price$530
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ96601
- Product descriptionFG-4592
- Packaging100mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ96601
- Product descriptionFG-4592
- Packaging250mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013712
- Product descriptionN-[(4-HYDROXY-1-METHYL-7-PHENOXY-3-ISOQUINOLINYL)CARBONYL]GLYCINE 95.00%
- Packaging10MG
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4187
- Product descriptionFG-4592(ASP1517)
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60208
- Product descriptionRoxadustat(FG-4592)
- Packaging20mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2588
- Product descriptionFG-4592-Roxadustat|ASP1517 99%
- Packaging100mg
- Price$357.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154738
- Product descriptionRoxadustat(FG-4592) >98%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154738
- Product descriptionRoxadustat(FG-4592) >98%
- Packaging250mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb154738
- Product descriptionRoxadustat(FG-4592) >98%
- Packaging1g
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH32910
- Product descriptionRoxadustat
- Packaging25mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH32910
- Product descriptionRoxadustat
- Packaging100mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH32910
- Product descriptionRoxadustat
- Packaging250mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH32910
- Product descriptionRoxadustat
- Packaging500mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH32910
- Product descriptionRoxadustat
- Packaging1g
- Price$550
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Activate Scientific | AS112067 | Roxadustat (FG-4592) 96% | 25mg | $209 | 2021-12-16 | Buy |
| Activate Scientific | AS112067 | Roxadustat (FG-4592) 96% | 100mg | $530 | 2021-12-16 | Buy |
| AK Scientific | J96601 | FG-4592 | 100mg | $144 | 2021-12-16 | Buy |
| AK Scientific | J96601 | FG-4592 | 250mg | $228 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0013712 | N-[(4-HYDROXY-1-METHYL-7-PHENOXY-3-ISOQUINOLINYL)CARBONYL]GLYCINE 95.00% | 10MG | $189 | 2021-12-16 | Buy |
| ApexBio Technology | A4187 | FG-4592(ASP1517) | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| Arctom | CFN60208 | Roxadustat(FG-4592) | 20mg | $188 | 2021-12-16 | Buy |
| Axon Medchem | Axon2588 | FG-4592-Roxadustat|ASP1517 99% | 100mg | $357.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154738 | Roxadustat(FG-4592) >98% | 100mg | $414.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154738 | Roxadustat(FG-4592) >98% | 250mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb154738 | Roxadustat(FG-4592) >98% | 1g | $1208.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH32910 | Roxadustat | 25mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH32910 | Roxadustat | 100mg | $140 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH32910 | Roxadustat | 250mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH32910 | Roxadustat | 500mg | $325 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH32910 | Roxadustat | 1g | $550 | 2021-12-16 | Buy |
Properties
Melting point :199-215°C
Boiling point :684.3±55.0 °C(Predicted)
Density :1.389
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :2.46±0.10(Predicted)
color :Off-white or white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChI :InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)
InChIKey :YOZBGTLTNGAVFU-UHFFFAOYSA-N
SMILES :C(O)(=O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC1=CC=CC=C1)C=C2)=O
Boiling point :684.3±55.0 °C(Predicted)
Density :1.389
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :2.46±0.10(Predicted)
color :Off-white or white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChI :InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)
InChIKey :YOZBGTLTNGAVFU-UHFFFAOYSA-N
SMILES :C(O)(=O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC1=CC=CC=C1)C=C2)=O
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||
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Description
Roxadustat is an orally administered, small molecule hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor that is being developed by FibroGen, in collaboration with Astellas and AstraZeneca, for the treatment of anaemia in patients with dialysis-dependent chronic kidney disease (CKD), non-dialysis-dependent CKD and in patients with myelodysplastic syndromes.Related product price
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Suppliers and manufacturers
Shanghai Famo Biotech Co Ltd
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Beijing Cooperate Pharmaceutical Co.,Ltd
Hangzhou FandaChem Co.,Ltd.
