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ChemicalBook >> CAS DataBase List >> SAHA-BPyne

SAHA-BPyne

SAHA-BPyne price.
  • $93 - $1139
  • Product name: SAHA-BPyne
  • CAS: 930772-88-6
  • MF: C27H31N3O5
  • MW: 477.55
  • EINECS:
  • MDL Number:
  • Synonyms:SAHA-BPyne;N-[4-[4-(hex-5-ynoylamino)benzoyl]phenyl]-N'-hydroxyoctanediamide;Octanediamide, N1-hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-;SAHA BPyne,SAHABPyne
Price3 Properties Safety Information Description
3 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 100μg
  • 1mg
  • 5mg
  • ManufacturerCayman Chemical
  • Product number10675
  • Product descriptionSAHA-BPyne ≥98%
  • Packaging100μg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10675
  • Product descriptionSAHA-BPyne
  • Packaging1mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10675
  • Product descriptionSAHA-BPyne
  • Packaging5mg
  • Price$1139
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10675 SAHA-BPyne ≥98% 100μg $93 2024-03-01 Buy
Cayman Chemical 10675 SAHA-BPyne 1mg $456 2024-03-01 Buy
Cayman Chemical 10675 SAHA-BPyne 5mg $1139 2024-03-01 Buy

Properties

Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 5 mg/ml; Methanol: 5 mg/ml
pka :9.48±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. SAHA-BPyne is a SAHA derivative with a benzophenone crosslinker and an alkyne tag intended to be used for profiling HDAC activities in proteomes and live cells. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions. SAHA-BPyne labels HDAC complex proteins both in proteomes at 100 nM and in live cells at 500 nM and demonstrates an IC50 value of ~3 μM for inhibition of HDAC activity in HeLa cell nuclear lysates in an HDAC activity assay.

Suppliers and manufacturers

TargetMol Chemicals Inc.
SAHA-BPyne
$1140.00 /1mg
SAHA-BPyne CAS:930772-88-6
Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. MedBioPharmaceutical Technology Inc TargetMol Chemicals Inc. Shanghai Yifei Biotechnology Co. , Ltd.