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ChemicalBook >> CAS DataBase List >> SGI 7079

SGI 7079

SGI 7079 price.
  • $32 - $1000
  • Product name: SGI 7079
  • CAS: 1239875-86-5
  • MF: C26H26FN7
  • MW: 455.53
  • EINECS:
  • MDL Number:MFCD28963942
  • Synonyms:3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile;SGI 7079;SGI-7079 /SGI7079;2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile;SGI-7079;SGI 7079;SGI7079;CS-2333;Benzeneacetonitrile, 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-;Tyro3,inhibit,SGI 7079,Inhibitor,Axl,SGI-7079,Mer,TAM Receptor,SGI7079
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number8620DG
  • Product descriptionCID46870258
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA771421
  • Product descriptionSGI-7079 98+%
  • Packaging2mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA771421
  • Product descriptionSGI-7079 98+%
  • Packaging5mg
  • Price$83
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA771421
  • Product descriptionSGI-7079 98+%
  • Packaging10mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA771421
  • Product descriptionSGI-7079 98+%
  • Packaging50mg
  • Price$425
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA771421
  • Product descriptionSGI-7079 98+%
  • Packaging100mg
  • Price$552
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004682
  • Product description2-(3-(2-((3-FLUORO-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO)-5-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)ACETONITRILE 95.00%
  • Packaging5MG
  • Price$499.22
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20111
  • Product descriptionSGI-7079 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20111
  • Product descriptionSGI-7079 ≥98%
  • Packaging5mg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20111
  • Product descriptionSGI-7079 ≥98%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20111
  • Product descriptionSGI-7079 ≥98%
  • Packaging25mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM152411
  • Product description2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile 98%
  • Packaging100mg
  • Price$471
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5607
  • Product descriptionSGI-7079 99.65%
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5607
  • Product descriptionSGI-7079 99.65%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5607
  • Product descriptionSGI-7079 99.65%
  • Packaging50mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5607
  • Product descriptionSGI-7079 99.65%
  • Packaging100mg
  • Price$960
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8620DG CID46870258 1mg $133 2021-12-16 Buy
Ambeed A771421 SGI-7079 98+% 2mg $57 2021-12-16 Buy
Ambeed A771421 SGI-7079 98+% 5mg $83 2021-12-16 Buy
Ambeed A771421 SGI-7079 98+% 10mg $130 2021-12-16 Buy
Ambeed A771421 SGI-7079 98+% 50mg $425 2021-12-16 Buy
Ambeed A771421 SGI-7079 98+% 100mg $552 2021-12-16 Buy
American Custom Chemicals Corporation INB0004682 2-(3-(2-((3-FLUORO-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO)-5-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)ACETONITRILE 95.00% 5MG $499.22 2021-12-16 Buy
Cayman Chemical 20111 SGI-7079 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 20111 SGI-7079 ≥98% 5mg $131 2024-03-01 Buy
Cayman Chemical 20111 SGI-7079 ≥98% 10mg $243 2024-03-01 Buy
Cayman Chemical 20111 SGI-7079 ≥98% 25mg $456 2024-03-01 Buy
Chemenu CM152411 2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile 98% 100mg $471 2021-12-16 Buy
ChemScene CS-5607 SGI-7079 99.65% 5mg $108 2021-12-16 Buy
ChemScene CS-5607 SGI-7079 99.65% 10mg $180 2021-12-16 Buy
ChemScene CS-5607 SGI-7079 99.65% 50mg $660 2021-12-16 Buy
ChemScene CS-5607 SGI-7079 99.65% 100mg $960 2021-12-16 Buy
Next Last

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC50s = 0.43 and 0.15 μM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G1 phase. SGI-7079 synergistically increases the potency of erlotinib on EGFR inhibition. In a mouse xenograft model of non-small cell lung cancer, SGI-7079 dose-dependently inhibits tumor growth, an effect that is greater when used in combination with erlotinib.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
SGI-7079
$56.00 /5mg
SGI-7079 CAS:1239875-86-5
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Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
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Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd